ES307376A1 - Procedimiento para la fabricacion de 1-glicosil-5-azacitosinas. - Google Patents

Procedimiento para la fabricacion de 1-glicosil-5-azacitosinas.

Info

Publication number
ES307376A1
ES307376A1 ES0307376A ES307376A ES307376A1 ES 307376 A1 ES307376 A1 ES 307376A1 ES 0307376 A ES0307376 A ES 0307376A ES 307376 A ES307376 A ES 307376A ES 307376 A1 ES307376 A1 ES 307376A1
Authority
ES
Spain
Prior art keywords
formula
general formula
same
radical
peracylglycosyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0307376A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Czech Academy of Sciences
Original Assignee
Czech Academy of Sciences
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Czech Academy of Sciences filed Critical Czech Academy of Sciences
Publication of ES307376A1 publication Critical patent/ES307376A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/12—Triazine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES0307376A 1963-12-22 1964-12-21 Procedimiento para la fabricacion de 1-glicosil-5-azacitosinas. Expired ES307376A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CS709363 1963-12-22

Publications (1)

Publication Number Publication Date
ES307376A1 true ES307376A1 (es) 1965-05-01

Family

ID=5419399

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0307376A Expired ES307376A1 (es) 1963-12-22 1964-12-21 Procedimiento para la fabricacion de 1-glicosil-5-azacitosinas.

Country Status (13)

Country Link
US (1) US3350388A (enExample)
AT (1) AT252458B (enExample)
BE (1) BE657451A (enExample)
BR (1) BR6465569D0 (enExample)
CH (1) CH479595A (enExample)
DE (1) DE1245384B (enExample)
DK (1) DK108500C (enExample)
ES (1) ES307376A1 (enExample)
FI (1) FI46389C (enExample)
FR (1) FR1450440A (enExample)
GB (1) GB1050899A (enExample)
IT (1) IT1043755B (enExample)
NL (1) NL6414959A (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1030970A (en) * 1964-05-15 1966-05-25 Inst Mikrobiologii Im Akad D K Method for the preparation of 2', 3', 5'-tri-o-acyl-6-azacytidines
DE2012888C3 (de) * 1970-03-14 1981-04-02 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Herstellung von 5-Azapyrimidinnucleosiden
US6943249B2 (en) 2003-03-17 2005-09-13 Ash Stevens, Inc. Methods for isolating crystalline Form I of 5-azacytidine
US6887855B2 (en) 2003-03-17 2005-05-03 Pharmion Corporation Forms of 5-azacytidine
US7038038B2 (en) * 2003-03-17 2006-05-02 Pharmion Corporation Synthesis of 5-azacytidine
US20060014949A1 (en) * 2004-07-13 2006-01-19 Supergen Inc. Compositions and formulations of decitabine polymorphs and methods of use thereof
US8741858B2 (en) 2007-09-21 2014-06-03 Zhongxu Ren Oligomer-nucleoside phosphate conjugates
MX2010003261A (es) * 2007-09-26 2010-08-18 Sinai School Medicine Analogos de azacitidina y usos de los mismos.
DK3782612T3 (da) 2008-05-15 2024-01-15 Celgene Corp Orale formuleringer af cytidinanaloger og fremgangsmåder til anvendelse deraf
EP2321302B1 (en) 2008-08-01 2014-10-29 Dr. Reddy's Laboratories Ltd. Azacitidine process and polymorphs
JP5650643B2 (ja) * 2008-08-08 2015-01-07 サイノファーム タイワン リミテッド ５−アザシトシンヌクレオシド及びその誘導体の製造方法
CN102438588B (zh) 2009-03-23 2015-04-01 埃姆比特生物科学公司 使用联合治疗法治疗疾病的方法
IT1399195B1 (it) 2010-03-30 2013-04-11 Chemi Spa Processo per la sintesi di azacitidina e decitabina
WO2012135405A1 (en) 2011-03-31 2012-10-04 Pharmion Llc Systhesis of 5-azacytidine
EP2833905B1 (en) 2012-04-04 2018-05-02 Halozyme, Inc. Combination therapy with hyaluronidase and a tumor-targeted taxane
CN108239128B (zh) 2016-12-23 2019-03-29 江苏奥赛康药业股份有限公司 β-核苷类化合物的制备方法
WO2019222435A1 (en) 2018-05-16 2019-11-21 Halozyme, Inc. Methods of selecting subjects for combination cancer therapy with a polymer-conjugated soluble ph20

Also Published As

Publication number Publication date
FR1450440A (fr) 1966-06-24
IT1043755B (it) 1980-02-29
FI46389C (fi) 1973-03-12
DE1245384B (de) 1967-07-27
GB1050899A (enExample)
US3350388A (en) 1967-10-31
AT252458B (de) 1967-02-27
FI46389B (enExample) 1972-11-30
BR6465569D0 (pt) 1973-08-02
NL6414959A (enExample) 1965-06-23
CH479595A (de) 1969-10-15
DK108500C (da) 1967-12-27
BE657451A (enExample) 1965-04-16

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