ES2987603T3 - Regulación genética de la respuesta inmunitaria por interacciones cromosómicas - Google Patents
Regulación genética de la respuesta inmunitaria por interacciones cromosómicas Download PDFInfo
- Publication number
- ES2987603T3 ES2987603T3 ES18815789T ES18815789T ES2987603T3 ES 2987603 T3 ES2987603 T3 ES 2987603T3 ES 18815789 T ES18815789 T ES 18815789T ES 18815789 T ES18815789 T ES 18815789T ES 2987603 T3 ES2987603 T3 ES 2987603T3
- Authority
- ES
- Spain
- Prior art keywords
- chromosomal
- sequence
- probe
- interactions
- nucleic acids
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762581287P | 2017-11-03 | 2017-11-03 | |
| GB2018052818 | 2018-10-03 | ||
| PCT/GB2018/053196 WO2019086898A2 (en) | 2017-11-03 | 2018-11-02 | Genetic regulation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2987603T3 true ES2987603T3 (es) | 2024-11-15 |
Family
ID=64661410
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES18815789T Active ES2987603T3 (es) | 2017-11-03 | 2018-11-02 | Regulación genética de la respuesta inmunitaria por interacciones cromosómicas |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US11840737B2 (OSRAM) |
| EP (1) | EP3704274B1 (OSRAM) |
| JP (2) | JP2021501592A (OSRAM) |
| KR (1) | KR102885025B1 (OSRAM) |
| CN (1) | CN111511930B (OSRAM) |
| AU (1) | AU2018361833B2 (OSRAM) |
| CA (1) | CA3078675A1 (OSRAM) |
| ES (1) | ES2987603T3 (OSRAM) |
| HU (1) | HUE066292T2 (OSRAM) |
| MY (1) | MY199800A (OSRAM) |
| PL (1) | PL3704274T3 (OSRAM) |
| SG (1) | SG11202003233YA (OSRAM) |
| WO (1) | WO2019086898A2 (OSRAM) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2604247B (en) * | 2019-09-11 | 2025-07-02 | Oxford BioDynamics PLC | Diagnostic chromosome marker |
| JP2023518424A (ja) * | 2020-03-17 | 2023-05-01 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | 治療に対するレスポンダを決定するための方法およびシステム |
| GB202008269D0 (en) * | 2020-06-02 | 2020-07-15 | Oxford Biodynamics Ltd | Detecting a chromosome marker |
| GB202016176D0 (en) * | 2020-10-12 | 2020-11-25 | Oxford BioDynamics PLC | Disease marker |
| TW202302862A (zh) * | 2021-03-04 | 2023-01-16 | 英商牛津生物力學公眾有限公司 | 染色體交互作用標記物 |
| TW202548029A (zh) * | 2024-04-12 | 2025-12-16 | 英商牛津生物力學公眾有限公司 | 染色體標記測試 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR036993A1 (es) * | 2001-04-02 | 2004-10-20 | Wyeth Corp | Uso de agentes que modulan la interaccion entre pd-1 y sus ligandos en la submodulacion de respuestas inmunologicas |
| GB0603251D0 (en) | 2006-02-17 | 2006-03-29 | Isis Innovation | DNA conformation |
| PT2121977T (pt) | 2007-01-11 | 2017-08-18 | Erasmus Univ Medical Center | Captura da conformação cromossómica circular (4c) |
| JP2011502108A (ja) * | 2007-10-15 | 2011-01-20 | 武田薬品工業株式会社 | 癌の予防・治療剤 |
| GB0810051D0 (en) | 2008-06-02 | 2008-07-09 | Oxford Biodynamics Ltd | Method of diagnosis |
| US8753892B2 (en) | 2009-05-12 | 2014-06-17 | Koninklijke Philips N.V. | Phosphodiesterase 4D7 as prostate cancer marker |
| EP3293275B1 (en) * | 2013-06-06 | 2021-08-04 | Dana-Farber Cancer Institute, Inc. | Compositions and methods for identification, assessment prevention, and treatment of cancer using pd-l1 isoforms |
| WO2015077414A1 (en) | 2013-11-20 | 2015-05-28 | Dana-Farber Cancer Institute, Inc. | Kynurenine pathway biomarkers predictive of anti-immune checkpoint inhibitor response |
| US11795496B2 (en) * | 2015-06-24 | 2023-10-24 | Oxford BioDynamics PLC | Epigenetic chromosome interactions |
-
2018
- 2018-11-02 US US16/760,541 patent/US11840737B2/en active Active
- 2018-11-02 WO PCT/GB2018/053196 patent/WO2019086898A2/en not_active Ceased
- 2018-11-02 CN CN201880083380.6A patent/CN111511930B/zh active Active
- 2018-11-02 ES ES18815789T patent/ES2987603T3/es active Active
- 2018-11-02 JP JP2020524490A patent/JP2021501592A/ja active Pending
- 2018-11-02 AU AU2018361833A patent/AU2018361833B2/en active Active
- 2018-11-02 EP EP18815789.5A patent/EP3704274B1/en active Active
- 2018-11-02 HU HUE18815789A patent/HUE066292T2/hu unknown
- 2018-11-02 CA CA3078675A patent/CA3078675A1/en active Pending
- 2018-11-02 KR KR1020207012736A patent/KR102885025B1/ko active Active
- 2018-11-02 PL PL18815789.5T patent/PL3704274T3/pl unknown
- 2018-11-02 MY MYPI2020002029A patent/MY199800A/en unknown
- 2018-11-02 SG SG11202003233YA patent/SG11202003233YA/en unknown
-
2023
- 2023-04-03 JP JP2023060384A patent/JP7631400B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2021501592A (ja) | 2021-01-21 |
| KR20200081380A (ko) | 2020-07-07 |
| NZ763540A (en) | 2025-03-28 |
| CA3078675A1 (en) | 2019-05-09 |
| AU2018361833A1 (en) | 2020-04-30 |
| EP3704274C0 (en) | 2024-04-17 |
| WO2019086898A3 (en) | 2019-06-13 |
| MY199800A (en) | 2023-11-23 |
| CN111511930B (zh) | 2024-11-22 |
| WO2019086898A2 (en) | 2019-05-09 |
| JP7631400B2 (ja) | 2025-02-18 |
| KR102885025B1 (ko) | 2025-11-11 |
| US20210230702A1 (en) | 2021-07-29 |
| EP3704274A2 (en) | 2020-09-09 |
| PL3704274T3 (pl) | 2024-07-08 |
| AU2018361833B2 (en) | 2021-04-22 |
| CN111511930A (zh) | 2020-08-07 |
| EP3704274B1 (en) | 2024-04-17 |
| US11840737B2 (en) | 2023-12-12 |
| JP2023082157A (ja) | 2023-06-13 |
| HUE066292T2 (hu) | 2024-07-28 |
| SG11202003233YA (en) | 2020-05-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR102622307B1 (ko) | 후성유전적 염색체 상호작용 | |
| Keogh et al. | High prevalence of focal and multi-focal somatic genetic variants in the human brain | |
| JP7631400B2 (ja) | 遺伝子調節 | |
| CN109880910A (zh) | 一种肿瘤突变负荷的检测位点组合、检测方法、检测试剂盒及系统 | |
| CN109661477B (zh) | 与乳腺癌相关的染色体相互作用的检测 | |
| HK1257433A1 (zh) | 免疫組庫正常性評估方法及其應用 | |
| AU2024203201A1 (en) | Multimodal analysis of circulating tumor nucleic acid molecules | |
| JP2023548419A (ja) | 非機能性転写体を用いたＰＡＲＰ阻害剤またはＤＮＡ損傷薬物感受性判定方法 ｛Ｍｅｔｈｏｄ ｆｏｒ Ｄｅｔｅｒｍｉｎｉｎｇ Ｓｅｎｓｉｔｉｖｉｔｙ ｔｏ ＰＡＲＰ ｉｎｈｉｂｉｔｏｒ ｏｒ ｇｅｎｏｔｏｘｉｃ ｄｒｕｇｓ ｂａｓｅｄ ｏｎ ｎｏｎ－ｆｕｎｃｔｉｏｎａｌ ｔｒａｎｓｃｒｉｐｔｓ｝ | |
| JP2025032205A (ja) | 前立腺がんおよびリンパ腫の染色体コンフォメーションマーカー | |
| JP2020537514A5 (OSRAM) | ||
| ES3029416T3 (en) | Chromosome interaction markers | |
| ES2971286T3 (es) | Aplicación de interacciones cromosómicas epigenéticas en diagnóstico de cáncer | |
| US20220333199A1 (en) | Diagnostic Chromosome Marker | |
| CN109609649B (zh) | 一种用于直肠腺癌诊疗的lncRNA | |
| CN105821131B (zh) | 骨肉瘤miRNA标记物 | |
| CN108018285B (zh) | 一种超敏感引物及其设计方法和应用 | |
| CA3099612C (en) | Method of cancer prognosis by assessing tumor variant diversity by means of establishing diversity indices | |
| WO2024259251A1 (en) | Method for hrd detection in targeted cfdna samples using de novo mutational signatures | |
| TW202548029A (zh) | 染色體標記測試 | |
| CN117795098A (zh) | 染色体相互作用标志物 | |
| HK40033107B (en) | Genetic regulation of immunoresponse by chromosome interactions | |
| HK40033107A (en) | Genetic regulation of immunoresponse by chromosome interactions | |
| HK40076364A (en) | Diagnostic chromosome marker | |
| CN111919257A (zh) | 降低测序数据中的噪声 |