AU2018361833B2 - Genetic regulation of immunoresponse by chromosome interactions - Google Patents
Genetic regulation of immunoresponse by chromosome interactions Download PDFInfo
- Publication number
- AU2018361833B2 AU2018361833B2 AU2018361833A AU2018361833A AU2018361833B2 AU 2018361833 B2 AU2018361833 B2 AU 2018361833B2 AU 2018361833 A AU2018361833 A AU 2018361833A AU 2018361833 A AU2018361833 A AU 2018361833A AU 2018361833 B2 AU2018361833 B2 AU 2018361833B2
- Authority
- AU
- Australia
- Prior art keywords
- responder
- chromosome
- probe
- interactions
- nucleic acids
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762581287P | 2017-11-03 | 2017-11-03 | |
| US62/581,287 | 2017-11-03 | ||
| GB2018052818 | 2018-10-03 | ||
| GBPCT/GB2018/052818 | 2018-10-03 | ||
| PCT/GB2018/053196 WO2019086898A2 (en) | 2017-11-03 | 2018-11-02 | Genetic regulation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2018361833A1 AU2018361833A1 (en) | 2020-04-30 |
| AU2018361833B2 true AU2018361833B2 (en) | 2021-04-22 |
Family
ID=64661410
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2018361833A Active AU2018361833B2 (en) | 2017-11-03 | 2018-11-02 | Genetic regulation of immunoresponse by chromosome interactions |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US11840737B2 (OSRAM) |
| EP (1) | EP3704274B1 (OSRAM) |
| JP (2) | JP2021501592A (OSRAM) |
| KR (1) | KR102885025B1 (OSRAM) |
| CN (1) | CN111511930B (OSRAM) |
| AU (1) | AU2018361833B2 (OSRAM) |
| CA (1) | CA3078675A1 (OSRAM) |
| ES (1) | ES2987603T3 (OSRAM) |
| HU (1) | HUE066292T2 (OSRAM) |
| MY (1) | MY199800A (OSRAM) |
| PL (1) | PL3704274T3 (OSRAM) |
| SG (1) | SG11202003233YA (OSRAM) |
| WO (1) | WO2019086898A2 (OSRAM) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2604247B (en) * | 2019-09-11 | 2025-07-02 | Oxford BioDynamics PLC | Diagnostic chromosome marker |
| JP2023518424A (ja) * | 2020-03-17 | 2023-05-01 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | 治療に対するレスポンダを決定するための方法およびシステム |
| GB202008269D0 (en) * | 2020-06-02 | 2020-07-15 | Oxford Biodynamics Ltd | Detecting a chromosome marker |
| GB202016176D0 (en) * | 2020-10-12 | 2020-11-25 | Oxford BioDynamics PLC | Disease marker |
| TW202302862A (zh) * | 2021-03-04 | 2023-01-16 | 英商牛津生物力學公眾有限公司 | 染色體交互作用標記物 |
| TW202548029A (zh) * | 2024-04-12 | 2025-12-16 | 英商牛津生物力學公眾有限公司 | 染色體標記測試 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016207661A1 (en) * | 2015-06-24 | 2016-12-29 | Oxford Biodynamics Limited | Detection processes using sites of chromosome interaction |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR036993A1 (es) * | 2001-04-02 | 2004-10-20 | Wyeth Corp | Uso de agentes que modulan la interaccion entre pd-1 y sus ligandos en la submodulacion de respuestas inmunologicas |
| GB0603251D0 (en) | 2006-02-17 | 2006-03-29 | Isis Innovation | DNA conformation |
| PT2121977T (pt) | 2007-01-11 | 2017-08-18 | Erasmus Univ Medical Center | Captura da conformação cromossómica circular (4c) |
| JP2011502108A (ja) * | 2007-10-15 | 2011-01-20 | 武田薬品工業株式会社 | 癌の予防・治療剤 |
| GB0810051D0 (en) | 2008-06-02 | 2008-07-09 | Oxford Biodynamics Ltd | Method of diagnosis |
| US8753892B2 (en) | 2009-05-12 | 2014-06-17 | Koninklijke Philips N.V. | Phosphodiesterase 4D7 as prostate cancer marker |
| EP3293275B1 (en) * | 2013-06-06 | 2021-08-04 | Dana-Farber Cancer Institute, Inc. | Compositions and methods for identification, assessment prevention, and treatment of cancer using pd-l1 isoforms |
| WO2015077414A1 (en) | 2013-11-20 | 2015-05-28 | Dana-Farber Cancer Institute, Inc. | Kynurenine pathway biomarkers predictive of anti-immune checkpoint inhibitor response |
-
2018
- 2018-11-02 US US16/760,541 patent/US11840737B2/en active Active
- 2018-11-02 WO PCT/GB2018/053196 patent/WO2019086898A2/en not_active Ceased
- 2018-11-02 CN CN201880083380.6A patent/CN111511930B/zh active Active
- 2018-11-02 ES ES18815789T patent/ES2987603T3/es active Active
- 2018-11-02 JP JP2020524490A patent/JP2021501592A/ja active Pending
- 2018-11-02 AU AU2018361833A patent/AU2018361833B2/en active Active
- 2018-11-02 EP EP18815789.5A patent/EP3704274B1/en active Active
- 2018-11-02 HU HUE18815789A patent/HUE066292T2/hu unknown
- 2018-11-02 CA CA3078675A patent/CA3078675A1/en active Pending
- 2018-11-02 KR KR1020207012736A patent/KR102885025B1/ko active Active
- 2018-11-02 PL PL18815789.5T patent/PL3704274T3/pl unknown
- 2018-11-02 MY MYPI2020002029A patent/MY199800A/en unknown
- 2018-11-02 SG SG11202003233YA patent/SG11202003233YA/en unknown
-
2023
- 2023-04-03 JP JP2023060384A patent/JP7631400B2/ja active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016207661A1 (en) * | 2015-06-24 | 2016-12-29 | Oxford Biodynamics Limited | Detection processes using sites of chromosome interaction |
| WO2016207653A1 (en) * | 2015-06-24 | 2016-12-29 | Oxford Biodynamics Limited | Detection of chromosome interactions |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2021501592A (ja) | 2021-01-21 |
| KR20200081380A (ko) | 2020-07-07 |
| NZ763540A (en) | 2025-03-28 |
| CA3078675A1 (en) | 2019-05-09 |
| AU2018361833A1 (en) | 2020-04-30 |
| EP3704274C0 (en) | 2024-04-17 |
| WO2019086898A3 (en) | 2019-06-13 |
| MY199800A (en) | 2023-11-23 |
| CN111511930B (zh) | 2024-11-22 |
| WO2019086898A2 (en) | 2019-05-09 |
| JP7631400B2 (ja) | 2025-02-18 |
| KR102885025B1 (ko) | 2025-11-11 |
| US20210230702A1 (en) | 2021-07-29 |
| EP3704274A2 (en) | 2020-09-09 |
| ES2987603T3 (es) | 2024-11-15 |
| PL3704274T3 (pl) | 2024-07-08 |
| CN111511930A (zh) | 2020-08-07 |
| EP3704274B1 (en) | 2024-04-17 |
| US11840737B2 (en) | 2023-12-12 |
| JP2023082157A (ja) | 2023-06-13 |
| HUE066292T2 (hu) | 2024-07-28 |
| SG11202003233YA (en) | 2020-05-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US7888497B2 (en) | Bioinformatically detectable group of novel regulatory oligonucleotides and uses thereof | |
| US20220119881A1 (en) | Systems and methods for sample preparation, sample sequencing, and sequencing data bias correction and quality control | |
| JP2024028940A (ja) | 核酸分子を分析するための方法およびシステム | |
| JP7631400B2 (ja) | 遺伝子調節 | |
| AU2007353824A1 (en) | Gene expression profiling for identification, monitoring, and treatment of cervical cancer | |
| EP2520661A1 (en) | Blood-based gene expression signatures in lung cancer | |
| CA3202510A1 (en) | Tl1a therapy compositions and methods of treatment therewith | |
| MPath et al. | MicroRNA (miRNA) expression profiling of peripheral blood samples in multiple myeloma patients using microarray | |
| Wang et al. | Circular RNA in invasive and recurrent clinical nonfunctioning pituitary adenomas: expression profiles and bioinformatic analysis | |
| US20250191759A1 (en) | Breast Cancer Diagnostic and Treatment | |
| US20180046754A1 (en) | Normalization methods for measuring gene copy number and expression | |
| CN111187840B (zh) | 一种用于早期乳腺癌诊断的生物标志物 | |
| Miliotis et al. | Determinants of gastric cancer immune escape identified from non-coding immune-landscape quantitative trait loci | |
| Zhou et al. | Screening prognosis‐related lncRNAs based on WGCNA to establish a new risk score for predicting prognosis in patients with hepatocellular carcinoma | |
| Chapaprieta et al. | Dual biological role and clinical impact of de novo chromatin activation in chronic lymphocytic leukemia | |
| CN109439743A (zh) | 一种重症哮喘的生物标志物及其应用 | |
| AU2019363806B2 (en) | Chromosome biomarker | |
| CN119736397A (zh) | Chsy3作为生物标志物在肝癌诊断和/或治疗中的应用 | |
| CN109988842B (zh) | 一种寡核苷酸标记探针原位检测pdl1的试剂组与应用 | |
| KR102546810B1 (ko) | 자궁경부암의 급성 종양 반응 진단용 조성물 | |
| CN106801101B (zh) | Med6基因作为急性心肌梗死风险预测标记物中的用途 | |
| AU2020344206B2 (en) | Diagnostic chromosome marker | |
| Kazemifard et al. | A prediction of the CRNDE role by modulating NF-κB pathway in inflammatory bowel disease (IBD) | |
| Ma et al. | Mechanisms and Targets of Vascular Natural Aging from a Systems Biology Perspective | |
| Dong et al. | Pathway-based network analysis of myeloma tumors: monoclonal gammopathy of unknown significance, smoldering multiple myeloma, and multiple myeloma |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HB | Alteration of name in register |
Owner name: OXFORD BIODYNAMICS PLC Free format text: FORMER NAME(S): OXFORD BIODYNAMICS LIMITED |
|
| FGA | Letters patent sealed or granted (standard patent) |