ES2979333T3 - Un nuevo compuesto de quinochalcona y usos del mismo para tratar el cáncer o la inflamación - Google Patents

Un nuevo compuesto de quinochalcona y usos del mismo para tratar el cáncer o la inflamación Download PDF

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Publication number
ES2979333T3
ES2979333T3 ES18889684T ES18889684T ES2979333T3 ES 2979333 T3 ES2979333 T3 ES 2979333T3 ES 18889684 T ES18889684 T ES 18889684T ES 18889684 T ES18889684 T ES 18889684T ES 2979333 T3 ES2979333 T3 ES 2979333T3
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ES
Spain
Prior art keywords
disease
ifn
syndrome
quinochalcone
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES18889684T
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English (en)
Spanish (es)
Inventor
Bo Huang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ji Chon Therapeutics Co Ltd
Original Assignee
Ji Chon Therapeutics Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ji Chon Therapeutics Co Ltd filed Critical Ji Chon Therapeutics Co Ltd
Application granted granted Critical
Publication of ES2979333T3 publication Critical patent/ES2979333T3/es
Active legal-status Critical Current
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/215—IFN-beta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/217—IFN-gamma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00—Quinones
    • C07C50/02—Quinones with monocyclic quinoid structure
    • C07C50/06—Quinones with monocyclic quinoid structure with unsaturation outside the quinoid structure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00—Quinones
    • C07C50/26—Quinones containing groups having oxygen atoms singly bound to carbon atoms
    • C07C50/30—Quinones containing groups having oxygen atoms singly bound to carbon atoms with polycyclic non-condensed quinoid structure

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ES18889684T 2017-12-11 2018-02-02 Un nuevo compuesto de quinochalcona y usos del mismo para tratar el cáncer o la inflamación Active ES2979333T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201711309136.0A CN109985030B (zh) 2017-12-11 2017-12-11 醌式查尔酮化合物在制备抗肿瘤药物中的应用
PCT/CN2018/075163 WO2019114125A1 (en) 2017-12-11 2018-02-02 A novel quinochalcone compound and uses thereof for treating cancer or inflammation

Publications (1)

Publication Number Publication Date
ES2979333T3 true ES2979333T3 (es) 2024-09-25

Family

ID=66819884

Family Applications (1)

Application Number Title Priority Date Filing Date
ES18889684T Active ES2979333T3 (es) 2017-12-11 2018-02-02 Un nuevo compuesto de quinochalcona y usos del mismo para tratar el cáncer o la inflamación

Country Status (6)

Country Link
US (1) US10988429B2 (enExample)
EP (1) EP3675841B1 (enExample)
JP (1) JP6987271B2 (enExample)
CN (1) CN109985030B (enExample)
ES (1) ES2979333T3 (enExample)
WO (1) WO2019114125A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114409522B (zh) * 2022-03-01 2023-08-15 贵州省天然产物研究中心 一种查尔酮衍生物及其制备方法与用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013054998A1 (ko) * 2011-10-13 2013-04-18 건국대학교 산학협력단 신규한 칼콘 유도체 및 이를 유효성분으로 하는 항암제 조성물
CN105085218B (zh) * 2014-05-22 2019-04-09 中国医学科学院药物研究所 一类a环具有甲基的醌式查尔酮化合物,制法与抗炎活性
CN105085219B (zh) * 2014-05-22 2019-04-09 中国医学科学院药物研究所 A环具有异戊烯基的醌式查尔酮化合物,制法与抗炎活性

Also Published As

Publication number Publication date
CN109985030B (zh) 2021-07-06
EP3675841C0 (en) 2024-04-10
EP3675841A4 (en) 2021-06-09
US10988429B2 (en) 2021-04-27
JP2021505691A (ja) 2021-02-18
EP3675841A1 (en) 2020-07-08
JP6987271B2 (ja) 2021-12-22
US20200377439A1 (en) 2020-12-03
CN109985030A (zh) 2019-07-09
WO2019114125A1 (en) 2019-06-20
EP3675841B1 (en) 2024-04-10

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