ES297721A1 - A procedure to produce heterocyclic compounds (Machine-translation by Google Translate, not legally binding) - Google Patents

A procedure to produce heterocyclic compounds (Machine-translation by Google Translate, not legally binding)

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Publication number
ES297721A1
ES297721A1 ES297721A ES297721A ES297721A1 ES 297721 A1 ES297721 A1 ES 297721A1 ES 297721 A ES297721 A ES 297721A ES 297721 A ES297721 A ES 297721A ES 297721 A1 ES297721 A1 ES 297721A1
Authority
ES
Spain
Prior art keywords
group
lower alkyl
hydrogen
formula
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES297721A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES297721A1 publication Critical patent/ES297721A1/en
Expired legal-status Critical Current

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  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

A process for producing heterocyclic compounds, of the general formula ** (See formula) ** where Z represents one of the groups ** (See formula) ** R1 is hydrogen, halogen or lower alkyl; R2, R3 and R4 each represent hydrogen or lower alkyl; A is a carbonyl group or a methylene group; B is a thio, sulfinyl or sulfonyl group; R5 is hydrogen, lower alkyl or carboxy lower alkyl; and R6 is hydrogen, lower alkyl or lower alkanoyloxy, and its acid addition salts, which process is characterized in that it consists in reacting a compound of the general formula ** (See formula) ** where R1, R3 and R4 have the above meaning and Hal represents halogen, with a mercaptoic acid of the general formula HS- Z'-COOH (III) where Z 'represents one of the groups ** (See formula) ** R5 has the meaning indicated above; Y R6 is hydrogen or lower alkyl, to form a compound of the formula ** (See formula) ** where R1, R3, R4 and Z ', have the above meaning, in oxidizing, if desired, the thio group of the last compound to convert it into a sulfonyl group, in reducing, and cyclizing the resulting compound, in converting, if desired, the carbonyl group of the resulting product into a methylene group, in oxidizing, if it is desired, a thio group to form a sulphinyl or sulphonyl group, in N-alkylated, if desired, an N-unsubstituted product, in introducing, if desired, an alkanoyloxy group as a substituent R6 and, if desired, in converting a resulting base in an acid addition salt. (Machine-translation by Google Translate, not legally binding)
ES297721A 1963-03-18 1964-03-17 A procedure to produce heterocyclic compounds (Machine-translation by Google Translate, not legally binding) Expired ES297721A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US26603063A 1963-03-18 1963-03-18

Publications (1)

Publication Number Publication Date
ES297721A1 true ES297721A1 (en) 1964-09-01

Family

ID=23012882

Family Applications (1)

Application Number Title Priority Date Filing Date
ES297721A Expired ES297721A1 (en) 1963-03-18 1964-03-17 A procedure to produce heterocyclic compounds (Machine-translation by Google Translate, not legally binding)

Country Status (2)

Country Link
DK (1) DK105982C (en)
ES (1) ES297721A1 (en)

Also Published As

Publication number Publication date
DK105982C (en) 1966-12-05

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