ES2965473T3 - Biomarcadores de microARN en suero circulante y métodos para el diagnóstico de la enfermedad de Alzheimer - Google Patents
Biomarcadores de microARN en suero circulante y métodos para el diagnóstico de la enfermedad de Alzheimer Download PDFInfo
- Publication number
- ES2965473T3 ES2965473T3 ES18742857T ES18742857T ES2965473T3 ES 2965473 T3 ES2965473 T3 ES 2965473T3 ES 18742857 T ES18742857 T ES 18742857T ES 18742857 T ES18742857 T ES 18742857T ES 2965473 T3 ES2965473 T3 ES 2965473T3
- Authority
- ES
- Spain
- Prior art keywords
- hsa
- mir
- seq
- mirnas
- mirna
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2821—Alzheimer
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Pathology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762521768P | 2017-06-19 | 2017-06-19 | |
| PCT/US2018/036377 WO2018236589A1 (en) | 2017-06-19 | 2018-06-07 | Circulating serum microrna biomarkers and methods for alzheimer's disease diagnosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2965473T3 true ES2965473T3 (es) | 2024-04-15 |
Family
ID=62952378
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES18742857T Active ES2965473T3 (es) | 2017-06-19 | 2018-06-07 | Biomarcadores de microARN en suero circulante y métodos para el diagnóstico de la enfermedad de Alzheimer |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US11634775B2 (enExample) |
| EP (2) | EP3642366B1 (enExample) |
| JP (1) | JP2020524509A (enExample) |
| ES (1) | ES2965473T3 (enExample) |
| WO (1) | WO2018236589A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2020000293A (es) * | 2017-07-12 | 2020-07-22 | Univ Texas Tech System | Microrna-455-3p como un marcador bioperiferico para la enfermedad de alzheimer. |
| CN111073973A (zh) * | 2019-12-10 | 2020-04-28 | 石河子大学 | 一种用于早期诊断2型糖尿病的microRNA序列及其应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009009457A1 (en) * | 2007-07-06 | 2009-01-15 | University Of Louisville Research Foundation, Inc. | Alzheimer's disease-specific micro-rna microarray and related methods |
| US20120108650A1 (en) * | 2010-10-29 | 2012-05-03 | Emory University | Micro rna markers and methods related thereto |
| EP2723894B1 (en) * | 2011-06-27 | 2016-05-11 | Eisai R&D Management Co., Ltd. | Microrna biomarkers indicative of alzheimer's disease |
| CA2838562A1 (en) * | 2011-08-08 | 2013-02-14 | Eugenia Wang | Biomarker for alzheimer's disease and/or mild cognitively impairment, and use thereof |
| WO2013024469A1 (en) | 2011-08-16 | 2013-02-21 | Rosetta Genomics Ltd. | Methods and compositions for diagnosis of alzheimer's desease |
| ES2813699T3 (es) | 2013-11-18 | 2021-03-24 | Diamir Llc | Métodos de uso de miARN de fluidos corporales para la detección y monitoreo de la enfermedad de Parkinson (PD) |
| WO2015179909A1 (en) | 2014-05-26 | 2015-12-03 | The University Of Melbourne | Mirna biomarkers of alzheimer's disease |
| JP6667813B2 (ja) | 2015-03-13 | 2020-03-18 | 国立大学法人広島大学 | アルツハイマー病又は軽度認知症の検出を補助する方法 |
| EP3985130A1 (en) * | 2016-02-05 | 2022-04-20 | St. John's University | Circulating serum microrna biomarkers and methods for determining parkinson's disease |
| EP3433381B1 (en) * | 2016-03-21 | 2024-07-24 | Diamir, LLC | Methods of using mirnas from bodily fluids for detection and differentiation of neurodegenerative diseases |
-
2018
- 2018-06-07 EP EP18742857.8A patent/EP3642366B1/en active Active
- 2018-06-07 EP EP23201936.4A patent/EP4289970B1/en active Active
- 2018-06-07 WO PCT/US2018/036377 patent/WO2018236589A1/en not_active Ceased
- 2018-06-07 US US16/623,937 patent/US11634775B2/en active Active
- 2018-06-07 ES ES18742857T patent/ES2965473T3/es active Active
- 2018-06-07 JP JP2019570475A patent/JP2020524509A/ja active Pending
-
2023
- 2023-03-13 US US18/182,868 patent/US12398427B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3642366A1 (en) | 2020-04-29 |
| EP4289970B1 (en) | 2025-12-17 |
| EP3642366B1 (en) | 2023-11-15 |
| US11634775B2 (en) | 2023-04-25 |
| EP3642366C0 (en) | 2023-11-15 |
| EP4289970A3 (en) | 2024-03-13 |
| US20240209444A1 (en) | 2024-06-27 |
| US12398427B2 (en) | 2025-08-26 |
| US20200190588A1 (en) | 2020-06-18 |
| WO2018236589A1 (en) | 2018-12-27 |
| JP2020524509A (ja) | 2020-08-20 |
| EP4289970A2 (en) | 2023-12-13 |
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