ES2952061T3 - Detección temprana de estadios preliminares de tumores de células germinales testiculares - Google Patents

Detección temprana de estadios preliminares de tumores de células germinales testiculares Download PDF

Info

Publication number
ES2952061T3
ES2952061T3 ES17800438T ES17800438T ES2952061T3 ES 2952061 T3 ES2952061 T3 ES 2952061T3 ES 17800438 T ES17800438 T ES 17800438T ES 17800438 T ES17800438 T ES 17800438T ES 2952061 T3 ES2952061 T3 ES 2952061T3
Authority
ES
Spain
Prior art keywords
mir
pcr
cdna
batch
blood serum
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES17800438T
Other languages
English (en)
Spanish (es)
Other versions
ES2952061T9 (es
Inventor
Meike Spiekermann
Nina Winter
Gazanfer Belge
Arlo Radtke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mirdetect GmbH
Original Assignee
Mirdetect GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mirdetect GmbH filed Critical Mirdetect GmbH
Application granted granted Critical
Publication of ES2952061T3 publication Critical patent/ES2952061T3/es
Publication of ES2952061T9 publication Critical patent/ES2952061T9/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6851Quantitative amplification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/178Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
ES17800438T 2016-11-02 2017-11-02 Detección temprana de estadios preliminares de tumores de células germinales testiculares Active ES2952061T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16196813 2016-11-02
PCT/EP2017/078079 WO2018083186A1 (en) 2016-11-02 2017-11-02 Early detection of preliminary stages of testicular germ cell tumors

Publications (2)

Publication Number Publication Date
ES2952061T3 true ES2952061T3 (es) 2023-10-26
ES2952061T9 ES2952061T9 (es) 2023-11-02

Family

ID=57223558

Family Applications (1)

Application Number Title Priority Date Filing Date
ES17800438T Active ES2952061T3 (es) 2016-11-02 2017-11-02 Detección temprana de estadios preliminares de tumores de células germinales testiculares

Country Status (9)

Country Link
US (1) US11643690B2 (enExample)
EP (1) EP3535417B9 (enExample)
JP (2) JP7391367B2 (enExample)
CN (1) CN109890979B (enExample)
AU (1) AU2017353410B2 (enExample)
CA (1) CA3038010A1 (enExample)
ES (1) ES2952061T3 (enExample)
PL (1) PL3535417T3 (enExample)
WO (1) WO2018083186A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116121372B (zh) * 2022-09-09 2025-09-19 清远市人民医院 一种鉴别中枢系统淋巴瘤和胶质母细胞瘤的miRNA标志物组合、试剂盒及应用
CN120519585B (zh) * 2025-07-23 2025-10-03 湖南工程学院 一种基于PER驱动Split G4/ThT级联检测睾丸生殖细胞瘤miRNA的探针体系及方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101363057B (zh) 2008-09-09 2011-11-09 浙江理工大学 一种生物样本中miRNA绝对表达量的检测方法
US20120107825A1 (en) * 2010-11-01 2012-05-03 Winger Edward E Methods and compositions for assessing patients with reproductive failure using immune cell-derived microrna
CN104080911A (zh) * 2011-11-30 2014-10-01 不来梅大学 miRNA在胎盘组织中的表达
CN104844566B (zh) * 2014-12-12 2018-05-18 合肥中科普瑞昇生物医药科技有限公司 一种新型结构的激酶抑制剂
DK3289095T5 (da) 2015-04-29 2019-07-29 Mirdetect Gmbh Detektering af nukleinsyremolekyler
US10136952B2 (en) * 2016-06-16 2018-11-27 Zimmer, Inc. Soft tissue balancing in articular surgery

Also Published As

Publication number Publication date
US11643690B2 (en) 2023-05-09
PL3535417T3 (pl) 2023-10-02
AU2017353410A1 (en) 2019-04-11
WO2018083186A1 (en) 2018-05-11
AU2017353410B2 (en) 2023-04-13
CA3038010A1 (en) 2018-05-11
EP3535417B1 (en) 2023-06-07
EP3535417B9 (en) 2023-10-04
US20200056243A1 (en) 2020-02-20
EP3535417A1 (en) 2019-09-11
JP2019532653A (ja) 2019-11-14
JP7391367B2 (ja) 2023-12-05
ES2952061T9 (es) 2023-11-02
CN109890979B (zh) 2023-06-16
CN109890979A (zh) 2019-06-14
JP2022088555A (ja) 2022-06-14

Similar Documents

Publication Publication Date Title
Hong et al. Systematic evaluation of multiple qPCR platforms, NanoString and miRNA-Seq for microRNA biomarker discovery in human biofluids
Tölle et al. Identification of microRNAs in blood and urine as tumour markers for the detection of urinary bladder cancer
Chen et al. A combination of Let-7d, Let-7g and Let-7i serves as a stable reference for normalization of serum microRNAs
ES2610245T3 (es) Perfilado de microARN para el diagnóstico en linfoma cutáneo de células T (CTCL)
Hatse et al. Circulating MicroRNAs as easy-to-measure aging biomarkers in older breast cancer patients: correlation with chronological age but not with fitness/frailty status
Liu et al. MicroRNAs in biofluids are novel tools for bladder cancer screening
Benoist et al. Prognostic value of novel liquid biomarkers in patients with metastatic castration-resistant prostate cancer treated with enzalutamide: a prospective observational study
WO2015153679A1 (en) Microrna assay for detection and management of pancreatic cancer precursors
ES2952061T3 (es) Detección temprana de estadios preliminares de tumores de células germinales testiculares
CN105647923A (zh) 与肝癌预后相关的血清miRNA标志物及其检测试剂盒的应用
ES2736850T3 (es) Detección de moléculas de ácido nucleico
Zhou et al. A method for extracting and characterizing RNA from urine: For downstream PCR and RNAseq analysis
EP2898097A1 (en) Microrna based method for diagnosis of colorectal tumors and of metastasis
HK40013273B (en) Early detection of preliminary stages of testicular germ cell tumors
HK40013273A (en) Early detection of preliminary stages of testicular germ cell tumors
EP4428248A1 (en) Method and reagent kit for assisting determination of lung cancer prognosis
HK1251262A1 (en) Detection of nucleic acid molecules
HK1251262B (en) Detection of nucleic acid molecules
BR112019005790B1 (pt) Método para detectar rnas pequenos ou proteínas associadas a rnas pequenos
CN109825596A (zh) 食管癌样本的内参miRNA及其应用
Al-Temimi et al. EVALUATION OF MICRORNA-21 IN INVASIVE DUCTAL CARCINOMA IN COMPARISON TO CLINICOPATHOLOGICAL STATUS BY STEM-LOOP RT-PCR PROCEDURE.
JP2006211994A (ja) 非小細胞肺癌に対する抗癌剤の抗癌特性決定方法