CN109890979B - 睾丸生殖细胞肿瘤的初期阶段的早期检测 - Google Patents

睾丸生殖细胞肿瘤的初期阶段的早期检测 Download PDF

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CN109890979B
CN109890979B CN201780067302.2A CN201780067302A CN109890979B CN 109890979 B CN109890979 B CN 109890979B CN 201780067302 A CN201780067302 A CN 201780067302A CN 109890979 B CN109890979 B CN 109890979B
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CN109890979A (zh
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迈克·施皮克曼
尼纳·温特
加赞费尔·贝尔格
阿洛·拉特克
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Mirdetect GmbH
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6851—Quantitative amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
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CN201780067302.2A 2016-11-02 2017-11-02 睾丸生殖细胞肿瘤的初期阶段的早期检测 Active CN109890979B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16196813.6 2016-11-02
EP16196813 2016-11-02
PCT/EP2017/078079 WO2018083186A1 (en) 2016-11-02 2017-11-02 Early detection of preliminary stages of testicular germ cell tumors

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CN109890979A CN109890979A (zh) 2019-06-14
CN109890979B true CN109890979B (zh) 2023-06-16

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US (1) US11643690B2 (enExample)
EP (1) EP3535417B9 (enExample)
JP (2) JP7391367B2 (enExample)
CN (1) CN109890979B (enExample)
AU (1) AU2017353410B2 (enExample)
CA (1) CA3038010A1 (enExample)
ES (1) ES2952061T3 (enExample)
PL (1) PL3535417T3 (enExample)
WO (1) WO2018083186A1 (enExample)

Families Citing this family (2)

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Publication number Priority date Publication date Assignee Title
CN116121372B (zh) * 2022-09-09 2025-09-19 清远市人民医院 一种鉴别中枢系统淋巴瘤和胶质母细胞瘤的miRNA标志物组合、试剂盒及应用
CN120519585B (zh) * 2025-07-23 2025-10-03 湖南工程学院 一种基于PER驱动Split G4/ThT级联检测睾丸生殖细胞瘤miRNA的探针体系及方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104039983A (zh) * 2011-10-28 2014-09-10 爱德华·E·维因格 采用免疫细胞源性的微小rna评估生殖障碍患者的方法与组合物
CN104080911A (zh) * 2011-11-30 2014-10-01 不来梅大学 miRNA在胎盘组织中的表达
CN104844566A (zh) * 2014-12-12 2015-08-19 中国科学院合肥物质科学研究院 一种新型结构的激酶抑制剂

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101363057B (zh) 2008-09-09 2011-11-09 浙江理工大学 一种生物样本中miRNA绝对表达量的检测方法
DK3289095T5 (da) 2015-04-29 2019-07-29 Mirdetect Gmbh Detektering af nukleinsyremolekyler
US10136952B2 (en) * 2016-06-16 2018-11-27 Zimmer, Inc. Soft tissue balancing in articular surgery

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104039983A (zh) * 2011-10-28 2014-09-10 爱德华·E·维因格 采用免疫细胞源性的微小rna评估生殖障碍患者的方法与组合物
CN104080911A (zh) * 2011-11-30 2014-10-01 不来梅大学 miRNA在胎盘组织中的表达
CN104844566A (zh) * 2014-12-12 2015-08-19 中国科学院合肥物质科学研究院 一种新型结构的激酶抑制剂

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
A pipeline to quantify serum and cerebrospinal fluid microRNAs for diagnosis and detection of relapse in paediatric malignant germ-cell tumours;Matthew J Murray等;《British Journal of Cancer》;20151215;第114卷;151-162 *
M. Spiekermann等.MicroRNA miR-371a-3p in serum of patients with germ cell tumours:evaluations for establishing a serum biomarker.《Andrology》.2014,第3卷78-84. *
MicroRNA miR-371a-3p in serum of patients with germ cell tumours:evaluations for establishing a serum biomarker;M. Spiekermann等;《Andrology》;20140904;第3卷;78-84 *
Pre-amplification in the context of high-throughput qPCR gene expression experiment;Vlasta Korenková等;《BMC Molecular Biology》;20150311;第16卷;5 *

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US11643690B2 (en) 2023-05-09
PL3535417T3 (pl) 2023-10-02
AU2017353410A1 (en) 2019-04-11
WO2018083186A1 (en) 2018-05-11
ES2952061T3 (es) 2023-10-26
AU2017353410B2 (en) 2023-04-13
CA3038010A1 (en) 2018-05-11
EP3535417B1 (en) 2023-06-07
EP3535417B9 (en) 2023-10-04
US20200056243A1 (en) 2020-02-20
EP3535417A1 (en) 2019-09-11
JP2019532653A (ja) 2019-11-14
JP7391367B2 (ja) 2023-12-05
ES2952061T9 (es) 2023-11-02
CN109890979A (zh) 2019-06-14
JP2022088555A (ja) 2022-06-14

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