ES295188A1 - Procedimiento para la preparación de sales puras, bien cristalizadas, difícilmente solubles de la fenoximetilpenicilina - Google Patents
Procedimiento para la preparación de sales puras, bien cristalizadas, difícilmente solubles de la fenoximetilpenicilinaInfo
- Publication number
- ES295188A1 ES295188A1 ES295188A ES295188A ES295188A1 ES 295188 A1 ES295188 A1 ES 295188A1 ES 295188 A ES295188 A ES 295188A ES 295188 A ES295188 A ES 295188A ES 295188 A1 ES295188 A1 ES 295188A1
- Authority
- ES
- Spain
- Prior art keywords
- benzimidazole
- component
- phenoxymethylpenicillin
- translation
- pure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003839 salts Chemical class 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- HYZJCKYKOHLVJF-UHFFFAOYSA-N 1H-benzimidazole Chemical compound C1=CC=C2NC=NC2=C1 HYZJCKYKOHLVJF-UHFFFAOYSA-N 0.000 abstract 4
- 229930195708 Penicillin V Natural products 0.000 abstract 3
- 229940056367 penicillin v Drugs 0.000 abstract 3
- BPLBGHOLXOTWMN-MBNYWOFBSA-N phenoxymethylpenicillin Chemical class N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)COC1=CC=CC=C1 BPLBGHOLXOTWMN-MBNYWOFBSA-N 0.000 abstract 3
- 229930182555 Penicillin Natural products 0.000 abstract 2
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 abstract 2
- 229940049954 penicillin Drugs 0.000 abstract 2
- 125000006283 4-chlorobenzyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1Cl)C([H])([H])* 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 150000001556 benzimidazoles Chemical class 0.000 abstract 1
- 239000013078 crystal Substances 0.000 abstract 1
- 239000012467 final product Substances 0.000 abstract 1
- 238000011081 inoculation Methods 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 125000000467 secondary amino group Chemical group [H]N([*:1])[*:2] 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 125000001302 tertiary amino group Chemical group 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/14—Radicals substituted by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT20863A AT232197B (de) | 1963-01-10 | 1963-01-10 | Verfahren zur Herstellung von reinen, gut kristallisierten, schwerlöslichen Salzen des Phenoxymethylpenicillins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES295188A1 true ES295188A1 (es) | 1964-03-16 |
Family
ID=3484355
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES295188A Expired ES295188A1 (es) | 1963-01-10 | 1964-01-10 | Procedimiento para la preparación de sales puras, bien cristalizadas, difícilmente solubles de la fenoximetilpenicilina |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US3288785A (instruction) |
| AT (1) | AT232197B (instruction) |
| BE (1) | BE642259A (instruction) |
| BR (1) | BR6455984D0 (instruction) |
| CH (1) | CH460015A (instruction) |
| DE (1) | DE1295559B (instruction) |
| DK (1) | DK116873B (instruction) |
| ES (1) | ES295188A1 (instruction) |
| FR (1) | FR1549156A (instruction) |
| GB (1) | GB1023385A (instruction) |
| NL (1) | NL302847A (instruction) |
| OA (1) | OA00410A (instruction) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1620450C3 (de) * | 1964-07-23 | 1976-01-02 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | 1 - (2- Hydroxybenzyl) -2-piperazinomethylbenzimidazole, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel |
| US4728741A (en) * | 1985-01-08 | 1988-03-01 | Smithkline Beckman Corporation | 1-substituted-2-mercapto benzimidazole compounds and intermediates |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE930927C (de) * | 1952-04-10 | 1955-07-28 | Gruenenthal Chemie | Verfahren zur Herstellung von gut vertraeglichen Penicillin-Antihistamin-Komplexverbindungen mit verlaengerter Wirkung |
| DE936872C (de) * | 1952-08-23 | 1955-12-22 | Gruenenthal Chemie | Verfahren zur Herstellung von schwerloeslichen Penicillinverbindungen |
| US2776279A (en) * | 1954-01-14 | 1957-01-01 | Gruenenthal Chemie | Benzimidazole-penicillin salt |
-
0
- NL NL302847D patent/NL302847A/xx unknown
-
1963
- 1963-01-10 AT AT20863A patent/AT232197B/de active
- 1963-11-13 DE DEB74253A patent/DE1295559B/de active Pending
-
1964
- 1964-01-06 CH CH3264A patent/CH460015A/de unknown
- 1964-01-06 US US336036A patent/US3288785A/en not_active Expired - Lifetime
- 1964-01-08 GB GB912/64A patent/GB1023385A/en not_active Expired
- 1964-01-08 BE BE642259A patent/BE642259A/xx unknown
- 1964-01-09 FR FR1549156D patent/FR1549156A/fr not_active Expired
- 1964-01-09 DK DK11864AA patent/DK116873B/da unknown
- 1964-01-10 BR BR155984/64A patent/BR6455984D0/pt unknown
- 1964-01-10 ES ES295188A patent/ES295188A1/es not_active Expired
- 1964-10-27 OA OA50487A patent/OA00410A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CH460015A (de) | 1968-07-31 |
| US3288785A (en) | 1966-11-29 |
| NL302847A (instruction) | |
| DE1295559B (de) | 1969-05-22 |
| OA00410A (fr) | 1966-05-15 |
| FR1549156A (instruction) | 1968-12-13 |
| DK116873B (da) | 1970-02-23 |
| BR6455984D0 (pt) | 1973-07-17 |
| BE642259A (instruction) | 1964-05-04 |
| GB1023385A (en) | 1966-03-23 |
| AT232197B (de) | 1964-03-10 |
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