ES2946673T3 - Agonistas del FPR2 de óxido de biaril dialquil fosfina - Google Patents
Agonistas del FPR2 de óxido de biaril dialquil fosfina Download PDFInfo
- Publication number
- ES2946673T3 ES2946673T3 ES20735802T ES20735802T ES2946673T3 ES 2946673 T3 ES2946673 T3 ES 2946673T3 ES 20735802 T ES20735802 T ES 20735802T ES 20735802 T ES20735802 T ES 20735802T ES 2946673 T3 ES2946673 T3 ES 2946673T3
- Authority
- ES
- Spain
- Prior art keywords
- halo
- pharmaceutically acceptable
- compound
- hydrogen
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/59—Hydrogenated pyridine rings
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962862897P | 2019-06-18 | 2019-06-18 | |
| PCT/US2020/037881 WO2020257161A1 (en) | 2019-06-18 | 2020-06-16 | Biaryl dialkyl phosphine oxide fpr2 agonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2946673T3 true ES2946673T3 (es) | 2023-07-24 |
Family
ID=71409568
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES20735802T Active ES2946673T3 (es) | 2019-06-18 | 2020-06-16 | Agonistas del FPR2 de óxido de biaril dialquil fosfina |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20220298186A1 (https=) |
| EP (1) | EP3986903B1 (https=) |
| JP (1) | JP7494224B2 (https=) |
| KR (1) | KR102953013B1 (https=) |
| CN (1) | CN114008059B (https=) |
| ES (1) | ES2946673T3 (https=) |
| WO (1) | WO2020257161A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102623473B1 (ko) * | 2017-06-09 | 2024-01-09 | 브리스톨-마이어스 스큅 컴퍼니 | 피페리디논 포르밀 펩티드 2 수용체 및 포르밀 펩티드 1 수용체 효능제 |
| CN113166134B (zh) | 2018-11-26 | 2024-06-14 | 百时美施贵宝公司 | 作为甲酰肽2受体激动剂的吡咯烷酮衍生物 |
| JP7802765B2 (ja) | 2020-08-12 | 2026-01-20 | ブリストル－マイヤーズ スクイブ カンパニー | オキソピロリジン尿素ｆｐｒ２アゴニスト |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10302500A1 (de) | 2003-01-23 | 2004-07-29 | Merck Patent Gmbh | Carbonsäureamidderivate |
| EP3414227B1 (en) | 2015-12-10 | 2021-11-24 | Bristol-Myers Squibb Company | Piperidinone formyl peptide 2 receptor and formyl peptide 1 receptor agonists |
| KR102623473B1 (ko) * | 2017-06-09 | 2024-01-09 | 브리스톨-마이어스 스큅 컴퍼니 | 피페리디논 포르밀 펩티드 2 수용체 및 포르밀 펩티드 1 수용체 효능제 |
| US10676431B2 (en) * | 2018-03-05 | 2020-06-09 | Bristol-Myers Squibb Company | Phenylpyrrolidinone formyl peptide 2 receptor agonists |
-
2020
- 2020-06-16 WO PCT/US2020/037881 patent/WO2020257161A1/en not_active Ceased
- 2020-06-16 JP JP2021575327A patent/JP7494224B2/ja active Active
- 2020-06-16 ES ES20735802T patent/ES2946673T3/es active Active
- 2020-06-16 US US17/616,748 patent/US20220298186A1/en not_active Abandoned
- 2020-06-16 CN CN202080044033.XA patent/CN114008059B/zh active Active
- 2020-06-16 EP EP20735802.9A patent/EP3986903B1/en active Active
- 2020-06-16 KR KR1020227001291A patent/KR102953013B1/ko active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2020257161A1 (en) | 2020-12-24 |
| CN114008059B (zh) | 2024-03-12 |
| KR20220024551A (ko) | 2022-03-03 |
| JP7494224B2 (ja) | 2024-06-03 |
| EP3986903B1 (en) | 2023-05-10 |
| CN114008059A (zh) | 2022-02-01 |
| EP3986903A1 (en) | 2022-04-27 |
| US20220298186A1 (en) | 2022-09-22 |
| JP2022537350A (ja) | 2022-08-25 |
| KR102953013B1 (ko) | 2026-04-14 |
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