ES2902982T3 - Un método y sistema para determinar un valor corregido de los datos de relaxometría de resonancia magnética del tejido visceral de un sujeto para el líquido extracelular basado en un contenido de hierro normal para el tejido visceral - Google Patents

Un método y sistema para determinar un valor corregido de los datos de relaxometría de resonancia magnética del tejido visceral de un sujeto para el líquido extracelular basado en un contenido de hierro normal para el tejido visceral Download PDF

Info

Publication number
ES2902982T3
ES2902982T3 ES14711591T ES14711591T ES2902982T3 ES 2902982 T3 ES2902982 T3 ES 2902982T3 ES 14711591 T ES14711591 T ES 14711591T ES 14711591 T ES14711591 T ES 14711591T ES 2902982 T3 ES2902982 T3 ES 2902982T3
Authority
ES
Spain
Prior art keywords
visceral tissue
extracellular fluid
iron
liver
subject
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES14711591T
Other languages
English (en)
Spanish (es)
Inventor
Elizabeth Tunnicliffe
Matthew Robson
Rajarshi Banerjee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oxford University Innovation Ltd
Original Assignee
Oxford University Innovation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oxford University Innovation Ltd filed Critical Oxford University Innovation Ltd
Application granted granted Critical
Publication of ES2902982T3 publication Critical patent/ES2902982T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/50—NMR imaging systems based on the determination of relaxation times, e.g. T1 measurement by IR sequences; T2 measurement by multiple-echo sequences
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
    • A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0033—Features or image-related aspects of imaging apparatus, e.g. for MRI, optical tomography or impedance tomography apparatus; Arrangements of imaging apparatus in a room
    • A61B5/004—Features or image-related aspects of imaging apparatus, e.g. for MRI, optical tomography or impedance tomography apparatus; Arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part
    • A61B5/0044—Features or image-related aspects of imaging apparatus, e.g. for MRI, optical tomography or impedance tomography apparatus; Arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part for the heart
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
    • A61B5/1451—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/42—Detecting, measuring or recording for evaluating the gastrointestinal, the endocrine or the exocrine systems
    • A61B5/4222—Evaluating particular parts, e.g. particular organs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/42—Detecting, measuring or recording for evaluating the gastrointestinal, the endocrine or the exocrine systems
    • A61B5/4222—Evaluating particular parts, e.g. particular organs
    • A61B5/4244—Evaluating particular parts, e.g. particular organs liver
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/448—Relaxometry, i.e. quantification of relaxation times or spin density
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2576/00—Medical imaging apparatus involving image processing or analysis
    • A61B2576/02—Medical imaging apparatus involving image processing or analysis specially adapted for a particular organ or body part
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2576/00—Medical imaging apparatus involving image processing or analysis
    • A61B2576/02—Medical imaging apparatus involving image processing or analysis specially adapted for a particular organ or body part
    • A61B2576/023—Medical imaging apparatus involving image processing or analysis specially adapted for a particular organ or body part for the heart
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10072—Tomographic images
    • G06T2207/10088—Magnetic resonance imaging [MRI]
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30048—Heart; Cardiac
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30056—Liver; Hepatic

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Surgery (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Radiology & Medical Imaging (AREA)
  • High Energy & Nuclear Physics (AREA)
  • General Physics & Mathematics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Optics & Photonics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Physiology (AREA)
  • Quality & Reliability (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Theoretical Computer Science (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
ES14711591T 2013-03-15 2014-03-14 Un método y sistema para determinar un valor corregido de los datos de relaxometría de resonancia magnética del tejido visceral de un sujeto para el líquido extracelular basado en un contenido de hierro normal para el tejido visceral Active ES2902982T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1304728.7A GB201304728D0 (en) 2013-03-15 2013-03-15 Medical imaging
PCT/GB2014/050815 WO2014140635A1 (en) 2013-03-15 2014-03-14 Medical imaging

Publications (1)

Publication Number Publication Date
ES2902982T3 true ES2902982T3 (es) 2022-03-30

Family

ID=48226431

Family Applications (1)

Application Number Title Priority Date Filing Date
ES14711591T Active ES2902982T3 (es) 2013-03-15 2014-03-14 Un método y sistema para determinar un valor corregido de los datos de relaxometría de resonancia magnética del tejido visceral de un sujeto para el líquido extracelular basado en un contenido de hierro normal para el tejido visceral

Country Status (12)

Country Link
US (1) US10162031B2 (enExample)
EP (1) EP2967419B1 (enExample)
JP (1) JP6392256B2 (enExample)
AU (1) AU2014229726B2 (enExample)
CA (1) CA2906163C (enExample)
ES (1) ES2902982T3 (enExample)
GB (2) GB201304728D0 (enExample)
MY (1) MY170136A (enExample)
PL (1) PL2967419T3 (enExample)
PT (1) PT2967419T (enExample)
SG (1) SG11201507628WA (enExample)
WO (1) WO2014140635A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201121406D0 (en) 2011-12-13 2012-01-25 Isis Innovation Systems and methods
GB201121404D0 (en) 2011-12-13 2012-01-25 Isis Innovation Diagnosis
GB201304728D0 (en) 2013-03-15 2013-05-01 Isis Innovation Medical imaging
GB2524587A (en) * 2014-03-28 2015-09-30 Perspectum Diagnostics Ltd Method and apparatus for non-invasive detection of inflammation of a visceral organ
GB201406304D0 (en) * 2014-04-08 2014-05-21 Isis Innovation Medical imaging
ES2822201T3 (es) * 2014-06-12 2021-04-29 Commissariat Energie Atomique Método de IRM para cuantificar la cantidad de hierro en tejidos utilizando difusión por imágenes de resonancia magnética
WO2018050672A1 (en) * 2016-09-13 2018-03-22 Institut National De La Sante Et De La Recherche Medicale (Inserm) Method for post-processing mri images to obtain hepatic perfusion and transport parameters
WO2018083504A1 (en) * 2016-11-07 2018-05-11 Oxford University Innovation Limited Correction method for magnetic resonance t1-mapping of visceral organs in the presence of elevated iron and elevated fat levels, and in the presence of off-resonance frequencies
CN110352034A (zh) * 2016-12-06 2019-10-18 达米雅恩公司 用于识别脑病症的方法和系统
US10613173B2 (en) 2017-04-07 2020-04-07 Siemens Healthcare Gmbh Method and magnetic resonance apparatus for generating a fat fraction-corrected T1 parameter map
DE102018209584A1 (de) * 2018-06-14 2019-12-19 Siemens Healthcare Gmbh Magnetresonanz-Fingerprinting-Verfahren
EP3629048A1 (de) 2018-09-27 2020-04-01 Siemens Healthcare GmbH Niederfeld-magnetresonanz-fingerprinting
EP3845919B1 (en) * 2020-01-03 2025-04-23 Siemens Healthineers AG Method for reducing the effects of b0-inhomogeneity in magnetic resonance imaging
WO2022076775A1 (en) * 2020-10-09 2022-04-14 Massachusetts Institute Of Technology Methods and systems for assessment of liver fibrosis and steatosis
GB2603896B (en) * 2021-02-12 2024-01-10 Perspectum Ltd Method of analysing medical images

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02243134A (ja) 1989-03-17 1990-09-27 Toshiba Corp 磁気共鳴イメージング装置
US5322682A (en) 1992-08-06 1994-06-21 The Regents Of The University Of California Method for quantitatively measuring and mapping stored iron in tissue using MRI
JPH0779939A (ja) * 1993-09-14 1995-03-28 Toshiba Corp 磁気共鳴診断装置
US5908386A (en) 1995-12-14 1999-06-01 Regents Of The Universotiy Of Minnesota Fast MRI for assessment of myocardial perfusion with arrythmia insensitive magnetization preparation
US5993398A (en) 1998-04-10 1999-11-30 Alperin; Noam Method of measuring intracranial pressure
US6245027B1 (en) 1998-04-10 2001-06-12 Noam Alperin Method of measuring intracranial pressure
DK1218766T3 (da) * 1999-08-24 2007-02-26 Resonance Health Analysis Serv Fremgangsmåde til kortlægning af longitudinale protonrelaksationstidskonstanter eller funktioner deraf i et målemne der er underlagt lokaliseret bevægelse, under anvendelse af kernemagnetisk resonansbilleddannelse
US7572231B2 (en) 2000-01-31 2009-08-11 Pearlman Justin D Method of and system for signal separation during multivariate physiological monitoring
US20040102692A1 (en) * 2002-11-27 2004-05-27 General Electric Company Magnetic resonance imaging system and methods for the detection of brain iron deposits
US6798199B2 (en) 2003-02-06 2004-09-28 Siemens Medical Solutions Usa, Inc. Method for synchronizing magnetic resonance imaging data to body motion
CN1973211A (zh) 2004-05-14 2007-05-30 皇家飞利浦电子股份有限公司 涉及k－空间中心过度采样的非笛卡尔轨迹的对比度预备mri
ITPI20050053A1 (it) * 2005-05-12 2006-11-13 Cnr Consiglio Naz Delle Ricerche Apparecchiatura per la valutazione dell' accumulo marziale nel miocardio mediante elaborazione di immagini di risonanza magnetica
US7468605B2 (en) * 2006-04-25 2008-12-23 The Board Of Trustees Of The Leland Stanford Junior University Simultaneous chemical species separation and T2* measurement using MRI
US20080150532A1 (en) 2006-12-21 2008-06-26 General Electric Company Method and apparatus for measuring t1 relaxation
US8727998B2 (en) 2007-05-16 2014-05-20 Mayo Foundation For Medical Education And Research Portal vein pressure measurement using elastography
SE531190C2 (sv) * 2007-05-31 2009-01-13 Colloidal Resource Ab Metod, system, datoravläsbart medium och användning för magnetisk resonanstomografi
WO2009127827A1 (en) * 2008-04-18 2009-10-22 The University Of Manchester Imaging technique
JP5537142B2 (ja) 2009-02-05 2014-07-02 株式会社東芝 磁気共鳴イメージング装置及び磁気共鳴撮像方法
DE102009011382A1 (de) 2009-03-05 2010-09-09 Rheinisch-Westfälische Technische Hochschule Aachen Verfahren und Vorrichtung zur Quantifizierung der Bildgüte und zur bewegungssynchronen Erfassung einer tomografischen Schnittaufnahme eines Objektes
US20110028828A1 (en) 2009-08-01 2011-02-03 Dania Daye T1 rho magnetic resonance imaging for staging of hepatic fibrosis
DE102010001145A1 (de) 2010-01-22 2011-07-28 Siemens Aktiengesellschaft, 80333 Verfahren und Vorrichtung zur Magnetresonanzbildgebung zum Erstellen von T1-Karten
EP2627246B1 (en) * 2010-10-14 2020-03-04 Syntheticmr AB Methods and apparatuses for relating multiple magnetic resonance physical parameters to myelin content in the brain
ES2585329T3 (es) 2010-11-29 2016-10-05 Crown Packaging Technology, Inc. Cierre
WO2013046158A2 (en) 2011-09-28 2013-04-04 Koninklijke Philips Electronics N.V. Method and system for quantifying hepatic fat in humans
GB201121406D0 (en) 2011-12-13 2012-01-25 Isis Innovation Systems and methods
GB201121404D0 (en) 2011-12-13 2012-01-25 Isis Innovation Diagnosis
EP2873017B1 (en) 2012-07-11 2021-09-01 University of Mississippi Medical Center Method for the detection and staging of liver fibrosis from image acquired data
GB201304728D0 (en) 2013-03-15 2013-05-01 Isis Innovation Medical imaging
GB2524587A (en) 2014-03-28 2015-09-30 Perspectum Diagnostics Ltd Method and apparatus for non-invasive detection of inflammation of a visceral organ
GB201406304D0 (en) 2014-04-08 2014-05-21 Isis Innovation Medical imaging

Also Published As

Publication number Publication date
AU2014229726B2 (en) 2019-06-06
GB201404628D0 (en) 2014-04-30
HK1213459A1 (en) 2016-07-08
PL2967419T3 (pl) 2022-02-14
GB2513474B (en) 2017-11-29
US10162031B2 (en) 2018-12-25
MY170136A (en) 2019-07-06
JP6392256B2 (ja) 2018-09-19
EP2967419B1 (en) 2021-10-20
GB2513474A (en) 2014-10-29
US20160025831A1 (en) 2016-01-28
GB201304728D0 (en) 2013-05-01
AU2014229726A1 (en) 2015-09-10
CA2906163A1 (en) 2014-09-18
CA2906163C (en) 2022-04-05
WO2014140635A1 (en) 2014-09-18
JP2016513514A (ja) 2016-05-16
EP2967419A1 (en) 2016-01-20
SG11201507628WA (en) 2015-10-29
PT2967419T (pt) 2022-01-20

Similar Documents

Publication Publication Date Title
ES2902982T3 (es) Un método y sistema para determinar un valor corregido de los datos de relaxometría de resonancia magnética del tejido visceral de un sujeto para el líquido extracelular basado en un contenido de hierro normal para el tejido visceral
Cox et al. Multiparametric renal magnetic resonance imaging: validation, interventions, and alterations in chronic kidney disease
Morrell et al. Magnetic resonance imaging of the fibrotic kidney
Tang et al. Noninvasive detection of extracellular pH in human benign and malignant liver tumors using CEST MRI
US10575771B2 (en) Multi-parametric magnetic resonance diagnosis and staging of liver disease
Feier et al. The diagnostic efficacy of quantitative liver MR imaging with diffusion-weighted, SWI, and hepato-specific contrast-enhanced sequences in staging liver fibrosis—a multiparametric approach
Smith et al. Rapid, high-resolution quantitative magnetization transfer MRI of the human spinal cord
US10228432B2 (en) Systems and methods for gated mapping of T1 values in abdominal visceral organs
Yarnykh et al. Fast macromolecular proton fraction mapping of the human liver in vivo for quantitative assessment of hepatic fibrosis
US9232907B2 (en) System, method and computer-accessible medium for utilizing cardiac output to improve measurement of tracer input function in dynamic contrast-enhanced magnetic resonance imaging
WO2015144916A1 (en) Method and apparatus for non-invasive detection of inflammation of a visceral organ
Kodama et al. Dynamic nuclear polarization magnetic resonance imaging and the oxygen-sensitive paramagnetic agent OX63 provide a noninvasiveáquantitative evaluation of kidneyáhypoxia in diabetic mice
Bechtel et al. Establishing a hemoglobin adjustment for 129Xe gas exchange MRI and MRS
CN110168394B (zh) 存在提高的铁和提高的脂肪水平且存在非共振频率的情况下用于内脏器官的磁共振t1-映射的修正方法
ES2979046T3 (es) Un procedimiento para posprocesar imágenes de resonancia magnética hepática para obtener un mapa reconstruido de la susceptibilidad magnética interna
Dillman et al. Quantitative abdominal magnetic resonance imaging in children—special considerations
Niendorf et al. Magnetic resonance imaging of renal oxygenation
Xie et al. Series of intravoxel incoherent motion and T2* magnetic resonance imaging mapping in detection of liver perfusion changes and regeneration among partial hepatectomy in sprague-dawley rats
HK1213459B (en) A method and system for determiing a corrected value of magnetic resonance relaxometry data of a subject's visceral tissue for extracellular fluid based on a normal iron content for the visceral tissue
Couch et al. Pulmonary Imaging Using 19F MRI of Inert Fluorinated Gases
Albatany et al. Brain pH Measurement Using AACID CEST MRI Incorporating the 2 ppm Amine Resonance. Tomography 2022, 8, 730–739
dos Santos Periquito Development of diffusion weighted magnetic resonance methodology and its application in renal imaging
Hormuth et al. Quantitative imaging using MRI
Periquito Development of diffusion weighted magnetic resonance methodology and its application in renal imaging
Erdmann Seeliger et al. Renal MRI: from Nephron to NMR Signal