ES288219A1 - Procedimiento de preparación de compuestos de 2-guanidinoalcohil-1,4-benzodioxano - Google Patents
Procedimiento de preparación de compuestos de 2-guanidinoalcohil-1,4-benzodioxanoInfo
- Publication number
- ES288219A1 ES288219A1 ES288219A ES288219A ES288219A1 ES 288219 A1 ES288219 A1 ES 288219A1 ES 288219 A ES288219 A ES 288219A ES 288219 A ES288219 A ES 288219A ES 288219 A1 ES288219 A1 ES 288219A1
- Authority
- ES
- Spain
- Prior art keywords
- compound
- formula
- salt
- cho
- lower alcohol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 title abstract 12
- 238000000034 method Methods 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 abstract 8
- 239000002253 acid Substances 0.000 abstract 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000012458 free base Substances 0.000 abstract 3
- DRSHXJFUUPIBHX-UHFFFAOYSA-N COc1ccc(cc1)N1N=CC2C=NC(Nc3cc(OC)c(OC)c(OCCCN4CCN(C)CC4)c3)=NC12 Chemical compound COc1ccc(cc1)N1N=CC2C=NC(Nc3cc(OC)c(OC)c(OCCCN4CCN(C)CC4)c3)=NC12 DRSHXJFUUPIBHX-UHFFFAOYSA-N 0.000 abstract 2
- 150000001540 azides Chemical class 0.000 abstract 2
- 150000007514 bases Chemical class 0.000 abstract 2
- 150000002431 hydrogen Chemical group 0.000 abstract 2
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 2
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- 101100516563 Caenorhabditis elegans nhr-6 gene Proteins 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical group [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 239000002585 base Substances 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical group BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Chemical group 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 150000007857 hydrazones Chemical class 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical group II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- XKJCHHZQLQNZHY-UHFFFAOYSA-N phthalimide Chemical compound C1=CC=C2C(=O)NC(=O)C2=C1 XKJCHHZQLQNZHY-UHFFFAOYSA-N 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1967762 | 1962-05-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES288219A1 true ES288219A1 (es) | 1963-11-01 |
Family
ID=10133350
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES288219A Expired ES288219A1 (es) | 1962-05-22 | 1963-05-21 | Procedimiento de preparación de compuestos de 2-guanidinoalcohil-1,4-benzodioxano |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US3247221A (en:Method) |
| AT (1) | AT251599B (en:Method) |
| BE (1) | BE632701A (en:Method) |
| BR (1) | BR6349262D0 (en:Method) |
| CH (1) | CH446389A (en:Method) |
| DE (1) | DE1518088A1 (en:Method) |
| DK (2) | DK107354C (en:Method) |
| ES (1) | ES288219A1 (en:Method) |
| FR (1) | FR3085M (en:Method) |
| GB (1) | GB1030752A (en:Method) |
| SE (1) | SE310498B (en:Method) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1004468A (en) * | 1963-08-21 | 1965-09-15 | Pfizer Ltd | Chroman derivatives |
| US3496183A (en) * | 1964-11-19 | 1970-02-17 | Egyt Gyogyszervegyeszeti Gyar | Beta-guanidino-ethyl-piperazine derivatives |
| FR1476752A (fr) * | 1966-02-28 | 1967-04-14 | Lipha | Nouveaux dérivés hétérocycliques de la guanidine et leurs procédés de préparation |
| GB1215152A (en) * | 1967-04-11 | 1970-12-09 | Science Union & Cie | Biguanide derivatives and pharmaceutical preparations containing them |
| US3882147A (en) * | 1969-06-09 | 1975-05-06 | Merck & Co Inc | 3-Hydroxy-3-(3,4-methylenedioxyphenylalkyl-3,4-dihydro-2H-1,5-benzodioxepin products |
| US3700691A (en) * | 1969-06-09 | 1972-10-24 | Frosst & Co Charles E | 3,3-disubstituted-3,4-dihydrobenzodioxepins |
| US3746724A (en) * | 1970-04-13 | 1973-07-17 | Ciba Geigy Corp | 3-guanidinoalkyl-thiophenes |
| US3907793A (en) * | 1972-05-01 | 1975-09-23 | Merck & Co Inc | 3-Hydroxy-3-morpholino-loweralkyl-3,4-dihydro-2H-1,5-benzodioxepin products |
| US4129655A (en) * | 1976-04-26 | 1978-12-12 | Ciba-Geigy Corporation | Neuroleptic 2-piperidinoalkyl-1,4-benzodioxans |
| US4039676A (en) * | 1975-06-23 | 1977-08-02 | Ciba-Geigy Corporation | 2-piperidinoalkyl-1,4-benzodioxans |
| US6162455A (en) * | 1997-01-22 | 2000-12-19 | American Cyanamid Company | Method for increasing lean meat, improving the lean meat to fat ratio and improving amino acid utilization in warm-blooded animals |
| WO2009089053A1 (en) * | 2008-01-11 | 2009-07-16 | Nektar Therapeutics Al, Corporation | Oligomer-guanidine class conjugates |
| CN105061392B (zh) * | 2015-07-20 | 2017-07-18 | 上海现代哈森（商丘）药业有限公司 | 一种硫酸胍生合成方法 |
-
0
- GB GB1030752D patent/GB1030752A/en active Active
- BE BE632701D patent/BE632701A/xx unknown
-
1963
- 1963-05-16 US US281048A patent/US3247221A/en not_active Expired - Lifetime
- 1963-05-18 DE DE19631518088 patent/DE1518088A1/de not_active Withdrawn
- 1963-05-21 DK DK241663AA patent/DK107354C/da active
- 1963-05-21 BR BR149262/63A patent/BR6349262D0/pt unknown
- 1963-05-21 ES ES288219A patent/ES288219A1/es not_active Expired
- 1963-05-21 DK DK177465AA patent/DK107355C/da active
- 1963-05-22 FR FR935737A patent/FR3085M/fr not_active Expired
- 1963-05-22 CH CH641863A patent/CH446389A/de unknown
- 1963-05-22 AT AT416463A patent/AT251599B/de active
- 1963-05-22 SE SE5695/63A patent/SE310498B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SE310498B (en:Method) | 1969-05-05 |
| DK107355C (da) | 1967-05-22 |
| FR3085M (fr) | 1965-01-25 |
| BR6349262D0 (pt) | 1973-08-02 |
| AT251599B (de) | 1967-01-10 |
| DE1518088A1 (de) | 1969-11-27 |
| BE632701A (en:Method) | |
| CH446389A (de) | 1967-11-15 |
| US3247221A (en) | 1966-04-19 |
| GB1030752A (en:Method) | |
| DK107354C (da) | 1967-05-22 |
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