ES281301A1 - Procedure for the preparation of derivatives of 1-dehidrotestosterona (Machine-translation by Google Translate, not legally binding)
- Google Patents
Procedure for the preparation of derivatives of 1-dehidrotestosterona (Machine-translation by Google Translate, not legally binding)
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck KGaA
Original Assignee
E Merck AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by E Merck AGfiledCriticalE Merck AG
Publication of ES281301A1publicationCriticalpatent/ES281301A1/en
Process for the preparation of 1-dehydro-testosterone derivatives, more specifically to prepare 17-dehydro-testosterone 17-acylates of the formula I ** (See formula) ** in which R = hydrocarbon radical with 8 to 30 carbon atoms, which may optionally be substituted by alkoxy groups with 1 to 8 carbon atoms, characterized by the fact that a) 1-dehydro-testosterone or its 17-acylate is esterified or transesterified with an acid of the formula R-COOH (R has the meaning already stated) or with a derivative of that acid suitable for esterification or transesterification, O well b) a steroid corresponding to formula I and saturated in position 1,2 is dehydrogenated in position 1,2, either microbiologically or chemically. O well c) a 2-X-3-keto-17-beta-OCOR-4-androstene, a 3-keto-4-X-17-beta-OCOR-1-androstene or a 2,4- or 2,5-di-octyl ester are dehydrohalogenated. X-3-keto-17beta-OCOR-androstane (where R has the meaning already stated: X-chlorine, bromine or iodine). (Machine-translation by Google Translate, not legally binding)
ES0281301A1961-10-051962-10-04Procedure for the preparation of derivatives of 1-dehidrotestosterona (Machine-translation by Google Translate, not legally binding)
ExpiredES281301A1
(en)
Procedure for the obtaining of organic acid esters of 3-beta-hydroxy-5-androsten-17-ona (dehidroepian-drosterone) with 3 to 14 atomos c in the rest of ester. (Machine-translation by Google Translate, not legally binding)
A procedure for preparing the 21-hydroxy steroids of the pregnan series esterified in the position 21. (Machine-translation by Google Translate, not legally binding)
A procedure for the preparation of new derivatives of alcoxi bottom of 3,7-dimetiloctan-1-al (Machine-translation by Google Translate, not legally binding)