ES2808049T3 - Acido nucleico antisentido - Google Patents
Acido nucleico antisentido Download PDFInfo
- Publication number
- ES2808049T3 ES2808049T3 ES16846578T ES16846578T ES2808049T3 ES 2808049 T3 ES2808049 T3 ES 2808049T3 ES 16846578 T ES16846578 T ES 16846578T ES 16846578 T ES16846578 T ES 16846578T ES 2808049 T3 ES2808049 T3 ES 2808049T3
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- Prior art keywords
- oligomer
- nucleotide sequence
- exon
- pharmaceutically acceptable
- hydrates
- Prior art date
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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- Medicinal Preparation (AREA)
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| PL3351633T3 (pl) * | 2015-09-15 | 2020-11-02 | Nippon Shinyaku Co., Ltd. | Antysensowny kwas nukleinowy |
| CN108137492B (zh) | 2015-10-09 | 2021-12-21 | 波涛生命科学有限公司 | 寡核苷酸组合物及其方法 |
| CN112955153A (zh) | 2018-08-02 | 2021-06-11 | 达因疗法公司 | 肌肉靶向复合物及其用于治疗肌养蛋白病的用途 |
| US11168141B2 (en) | 2018-08-02 | 2021-11-09 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating dystrophinopathies |
| US12018087B2 (en) | 2018-08-02 | 2024-06-25 | Dyne Therapeutics, Inc. | Muscle-targeting complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and methods of delivering oligonucleotide to a subject |
| CN112912499A (zh) | 2018-08-02 | 2021-06-04 | 达因疗法公司 | 肌肉靶向复合物及其用于治疗面肩肱型肌营养不良的用途 |
| GB201821269D0 (en) * | 2018-12-28 | 2019-02-13 | Nippon Shinyaku Co Ltd | Myostatin signal inhibitor |
| WO2022232478A1 (en) | 2021-04-30 | 2022-11-03 | Sarepta Therapeutics, Inc. | Treatment methods for muscular dystrophy |
| KR20240024176A (ko) * | 2021-06-23 | 2024-02-23 | 니뽄 신야쿠 가부시키가이샤 | 안티센스 올리고머의 조합 |
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| IL309936A (en) | 2021-07-09 | 2024-03-01 | Dyne Therapeutics Inc | Muscle targeting complexes and formulations for the treatment of dystrophinopathy |
| US11969475B2 (en) | 2021-07-09 | 2024-04-30 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy |
| US11638761B2 (en) | 2021-07-09 | 2023-05-02 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating Facioscapulohumeral muscular dystrophy |
| EP4458833A1 (en) | 2021-12-27 | 2024-11-06 | Nippon Shinyaku Co., Ltd. | Method for producing oligonucleic acid compound |
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| US8084601B2 (en) | 2008-09-11 | 2011-12-27 | Royal Holloway And Bedford New College Royal Holloway, University Of London | Oligomers |
| CA3066050A1 (en) * | 2008-10-24 | 2010-04-29 | Sarepta Therapeutics, Inc. | Multiple exon skipping compositions for dmd |
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| ITTO20090487A1 (it) * | 2009-06-26 | 2010-12-27 | Univ Ferrara | Oligonucleotidi antisenso atti ad indurre lo skipping esonico e loro impiego come medicamento per il trattamento della distrofia muscolare di duchenne (dmd) |
| US20120270930A1 (en) * | 2009-10-29 | 2012-10-25 | Academisch Ziekenhuis Leiden H.O.D.N. Lumc | Methods and compositions for dysferlin exon-skipping |
| SI2499249T1 (sl) | 2009-11-12 | 2019-02-28 | The University Of Western Australia, | Protismiselne molekule in postopki zdravljenja patologij |
| TWI541024B (zh) * | 2010-09-01 | 2016-07-11 | 日本新藥股份有限公司 | 反義核酸 |
| CA2826836A1 (en) | 2011-02-08 | 2012-08-16 | The Charlotte-Mecklenburg Hospital Authority D/B/A Carolinas Medical Center | Antisense oligonucleotides |
| CN117721110A (zh) * | 2011-12-28 | 2024-03-19 | 日本新药株式会社 | 反义核酸 |
| CA2862628C (en) | 2012-01-27 | 2021-08-24 | Prosensa Technologies B.V. | Rna modulating oligonucleotides with improved characteristics for the treatment of duchenne and becker muscular dystrophy |
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| MX373959B (es) | 2013-03-15 | 2020-07-13 | Sarepta Therapeutics Inc | Composición para usarse en el tratamiento de la distrofia muscular de duchenne (dmd). |
| WO2015137409A1 (ja) | 2014-03-12 | 2015-09-17 | 日本新薬株式会社 | アンチセンス核酸 |
| JP2015182145A (ja) | 2014-03-20 | 2015-10-22 | キヤノン株式会社 | ロボットシステムの制御方法、およびロボットシステム |
| SI3159409T1 (sl) | 2014-06-17 | 2020-02-28 | Nippon Shinyaku Co., Ltd. | Protismiselna nukleinska kislina za uporabo pri zdravljenju Duchennove mišične distrofije |
| PL3351633T3 (pl) * | 2015-09-15 | 2020-11-02 | Nippon Shinyaku Co., Ltd. | Antysensowny kwas nukleinowy |
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