ES2806723T3 - Compuestos de bis-piridazina y su uso en el tratamiento del cáncer - Google Patents
Compuestos de bis-piridazina y su uso en el tratamiento del cáncer Download PDFInfo
- Publication number
- ES2806723T3 ES2806723T3 ES16801774T ES16801774T ES2806723T3 ES 2806723 T3 ES2806723 T3 ES 2806723T3 ES 16801774 T ES16801774 T ES 16801774T ES 16801774 T ES16801774 T ES 16801774T ES 2806723 T3 ES2806723 T3 ES 2806723T3
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- Prior art keywords
- formula
- compound
- pyridazin
- pharmaceutically acceptable
- methoxy
- Prior art date
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1520959.6A GB201520959D0 (en) | 2015-11-27 | 2015-11-27 | Bis-pyridazine compounds and their use in treating cancer |
| PCT/EP2016/078899 WO2017089587A1 (en) | 2015-11-27 | 2016-11-25 | Bis-pyridazine compounds and their use in treating cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2806723T3 true ES2806723T3 (es) | 2021-02-18 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES16801774T Active ES2806723T3 (es) | 2015-11-27 | 2016-11-25 | Compuestos de bis-piridazina y su uso en el tratamiento del cáncer |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US10196382B2 (enExample) |
| EP (1) | EP3380468B8 (enExample) |
| JP (1) | JP2018535226A (enExample) |
| KR (1) | KR20180083426A (enExample) |
| CN (1) | CN108349951B (enExample) |
| AR (1) | AR106849A1 (enExample) |
| AU (1) | AU2016360970B2 (enExample) |
| CA (1) | CA3005102A1 (enExample) |
| DK (1) | DK3380468T3 (enExample) |
| ES (1) | ES2806723T3 (enExample) |
| GB (1) | GB201520959D0 (enExample) |
| IL (1) | IL259358A (enExample) |
| MX (1) | MX2018006374A (enExample) |
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| CN106552296B (zh) | 2015-09-29 | 2020-08-14 | 上海氪励铵勤科技发展有限公司 | 纳米粒子、其制备方法与结石取出装置及应用 |
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| US10323028B2 (en) | 2015-11-30 | 2019-06-18 | Astrazeneca Ab | 1,3,4-thiadiazole compounds and their use in treating cancer |
| KR20250137464A (ko) | 2024-03-11 | 2025-09-18 | 이석재 | 숏블라스트머신의 연마재탱크 |
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| CN108785305B (zh) | 2011-11-21 | 2021-10-29 | 卡利泰拉生物科技公司 | 谷氨酰胺酶的杂环抑制剂 |
| WO2014079011A1 (en) | 2012-11-22 | 2014-05-30 | Agios Pharmaceuticals, Inc. | Heterocyclic compounds for inhibiting glutaminase and their methods of use |
| KR20160100407A (ko) * | 2014-01-06 | 2016-08-23 | 리젠 파마슈티컬스 소시에떼 아노님 | 신규한 글루타미나제의 저해제 |
| GB201409624D0 (en) | 2014-05-30 | 2014-07-16 | Astrazeneca Ab | 1,3,4-thiadiazole compounds and their use in treating cancer |
| GB201520959D0 (en) | 2015-11-27 | 2016-01-13 | Astrazeneca Ab And Cancer Res Technology Ltd | Bis-pyridazine compounds and their use in treating cancer |
| US9938265B2 (en) | 2015-11-30 | 2018-04-10 | Astrazeneca Ab | 1,3,4-thiadiazole compounds and their use in treating cancer |
| TW201731511A (zh) | 2015-11-30 | 2017-09-16 | 阿斯特捷利康公司 | １，３，４-噻二唑化合物及其在治療癌症中之用途 |
| US10323028B2 (en) | 2015-11-30 | 2019-06-18 | Astrazeneca Ab | 1,3,4-thiadiazole compounds and their use in treating cancer |
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2019
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| AR106849A1 (es) | 2018-02-21 |
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| AU2016360970B2 (en) | 2019-11-07 |
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| IL259358A (en) | 2018-07-31 |
| US20190169172A1 (en) | 2019-06-06 |
| US10196382B2 (en) | 2019-02-05 |
| TW201731837A (zh) | 2017-09-16 |
| US20170152244A1 (en) | 2017-06-01 |
| WO2017089587A1 (en) | 2017-06-01 |
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| EP3380468B8 (en) | 2020-11-04 |
| EP3380468B1 (en) | 2020-05-20 |
| RU2018122012A (ru) | 2019-12-30 |
| EP3380468A1 (en) | 2018-10-03 |
| JP2018535226A (ja) | 2018-11-29 |
| AU2016360970A1 (en) | 2018-07-05 |
| SG11201803814SA (en) | 2018-06-28 |
| DK3380468T3 (da) | 2020-07-27 |
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