ES279129A1 - A procedure for the preparation of salts of addition of hydroxocobalamine (Machine-translation by Google Translate, not legally binding) - Google Patents

A procedure for the preparation of salts of addition of hydroxocobalamine (Machine-translation by Google Translate, not legally binding)

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Publication number
ES279129A1
ES279129A1 ES0279129A ES279129A ES279129A1 ES 279129 A1 ES279129 A1 ES 279129A1 ES 0279129 A ES0279129 A ES 0279129A ES 279129 A ES279129 A ES 279129A ES 279129 A1 ES279129 A1 ES 279129A1
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ES
Spain
Prior art keywords
addition
translation
preparation
machine
legally binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0279129A
Other languages
Spanish (es)
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Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to ES0279129A priority Critical patent/ES279129A1/en
Publication of ES279129A1 publication Critical patent/ES279129A1/en
Expired legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A process for the preparation of addition salts of hydroxocobalamin and of a strong organic acid, soluble in water, belonging to the group formed by the aspartic, glycolic, pantothenic and succinic acids, characterized in that the organic acid is progressively added to a solution of hydroxocobalamin, monitoring the pH until observing a sudden variation of pH that occurs sensibly at pH 6, because then an excess of acid is added, comprised substantially between 1/10 and 1/4 of the amount consumed previously, and because it is controlled the stability over time of the pH of the solution, followed by any further increase of the latter by the addition of a corresponding dose of acid, after which the crystallization of the formed salt is caused. (Machine-translation by Google Translate, not legally binding)
ES0279129A 1962-07-11 1962-07-11 A procedure for the preparation of salts of addition of hydroxocobalamine (Machine-translation by Google Translate, not legally binding) Expired ES279129A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES0279129A ES279129A1 (en) 1962-07-11 1962-07-11 A procedure for the preparation of salts of addition of hydroxocobalamine (Machine-translation by Google Translate, not legally binding)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES0279129A ES279129A1 (en) 1962-07-11 1962-07-11 A procedure for the preparation of salts of addition of hydroxocobalamine (Machine-translation by Google Translate, not legally binding)

Publications (1)

Publication Number Publication Date
ES279129A1 true ES279129A1 (en) 1962-11-01

Family

ID=34560677

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0279129A Expired ES279129A1 (en) 1962-07-11 1962-07-11 A procedure for the preparation of salts of addition of hydroxocobalamine (Machine-translation by Google Translate, not legally binding)

Country Status (1)

Country Link
ES (1) ES279129A1 (en)

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