ES2772701T3 - Uso de nucleosomas libres de células como biomarcadores en muestras de esputo - Google Patents
Uso de nucleosomas libres de células como biomarcadores en muestras de esputo Download PDFInfo
- Publication number
- ES2772701T3 ES2772701T3 ES16736594T ES16736594T ES2772701T3 ES 2772701 T3 ES2772701 T3 ES 2772701T3 ES 16736594 T ES16736594 T ES 16736594T ES 16736594 T ES16736594 T ES 16736594T ES 2772701 T3 ES2772701 T3 ES 2772701T3
- Authority
- ES
- Spain
- Prior art keywords
- cell
- epigenetic
- free
- nucleosome
- nucleosomes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6875—Nucleoproteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57488—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/12—Pulmonary diseases
- G01N2800/122—Chronic or obstructive airway disorders, e.g. asthma COPD
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Transplantation (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1511512.4A GB201511512D0 (en) | 2015-07-01 | 2015-07-01 | Use of cell-free nucleosomes as biomarkers |
PCT/GB2016/051994 WO2017001863A1 (en) | 2015-07-01 | 2016-07-01 | Use of cell-free nucleosomes as biomarkers in sputum samples |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2772701T3 true ES2772701T3 (es) | 2020-07-08 |
Family
ID=53872486
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES16736594T Active ES2772701T3 (es) | 2015-07-01 | 2016-07-01 | Uso de nucleosomas libres de células como biomarcadores en muestras de esputo |
Country Status (8)
Country | Link |
---|---|
US (1) | US20180306804A1 (ru) |
EP (1) | EP3317671B1 (ru) |
JP (1) | JP7094700B2 (ru) |
CN (1) | CN108450000A (ru) |
ES (1) | ES2772701T3 (ru) |
GB (1) | GB201511512D0 (ru) |
HK (1) | HK1255151A1 (ru) |
WO (1) | WO2017001863A1 (ru) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111918971A (zh) * | 2018-03-01 | 2020-11-10 | 埃皮塞弗公司 | 利用化学确定的重组核小体定量核小体修饰 |
US11154240B2 (en) | 2019-04-02 | 2021-10-26 | Kpn Innovations Llc | Methods and systems for utilizing diagnostics for informed vibrant constitutional guidance |
JP2023503379A (ja) * | 2019-12-02 | 2023-01-27 | ベルジアン ボリション エスアールエル | バイオマーカーとしての細胞外遊離ヌクレオソームの使用 |
US11289206B2 (en) | 2020-06-02 | 2022-03-29 | Kpn Innovations, Llc. | Artificial intelligence methods and systems for constitutional analysis using objective functions |
US11211158B1 (en) | 2020-08-31 | 2021-12-28 | Kpn Innovations, Llc. | System and method for representing an arranged list of provider aliment possibilities |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7229772B1 (en) * | 1998-03-18 | 2007-06-12 | Roche Diagnostics Gmbh | Detection of apoptotic products |
GB201012662D0 (en) * | 2010-07-28 | 2010-09-15 | Valirx Plc | Method for detecting the presence of a gynaecological growth |
GB201115095D0 (en) * | 2011-09-01 | 2011-10-19 | Singapore Volition Pte Ltd | Method for detecting nucleosomes containing nucleotides |
GB201115098D0 (en) * | 2011-09-01 | 2011-10-19 | Belgian Volition Sa | Method for detecting nucleosomes containing histone variants |
SG11201402982TA (en) * | 2011-12-07 | 2014-07-30 | Singapore Volition Pte Ltd | Method for detecting nucleosome adducts |
GB201303575D0 (en) * | 2013-02-28 | 2013-04-10 | Singapore Volition Pte Ltd | Method for detecting histone modifications in nucleosomes |
WO2015048535A1 (en) * | 2013-09-27 | 2015-04-02 | Natera, Inc. | Prenatal diagnostic resting standards |
-
2015
- 2015-07-01 GB GBGB1511512.4A patent/GB201511512D0/en not_active Ceased
-
2016
- 2016-07-01 JP JP2017568274A patent/JP7094700B2/ja active Active
- 2016-07-01 US US15/738,082 patent/US20180306804A1/en not_active Abandoned
- 2016-07-01 ES ES16736594T patent/ES2772701T3/es active Active
- 2016-07-01 WO PCT/GB2016/051994 patent/WO2017001863A1/en active Application Filing
- 2016-07-01 CN CN201680050736.7A patent/CN108450000A/zh active Pending
- 2016-07-01 EP EP16736594.9A patent/EP3317671B1/en active Active
-
2018
- 2018-11-08 HK HK18114236.5A patent/HK1255151A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
EP3317671A1 (en) | 2018-05-09 |
US20180306804A1 (en) | 2018-10-25 |
CN108450000A (zh) | 2018-08-24 |
WO2017001863A1 (en) | 2017-01-05 |
EP3317671B1 (en) | 2019-11-13 |
HK1255151A1 (zh) | 2019-08-09 |
GB201511512D0 (en) | 2015-08-12 |
JP2018529931A (ja) | 2018-10-11 |
JP7094700B2 (ja) | 2022-07-04 |
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