ES2763563T3 - Método - Google Patents

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Publication number
ES2763563T3
ES2763563T3 ES15816204T ES15816204T ES2763563T3 ES 2763563 T3 ES2763563 T3 ES 2763563T3 ES 15816204 T ES15816204 T ES 15816204T ES 15816204 T ES15816204 T ES 15816204T ES 2763563 T3 ES2763563 T3 ES 2763563T3
Authority
ES
Spain
Prior art keywords
protein
binding
library
binding agent
target
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES15816204T
Other languages
English (en)
Spanish (es)
Inventor
Csaba Jeney
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Actome GmbH
Original Assignee
Actome GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Actome GmbH filed Critical Actome GmbH
Application granted granted Critical
Publication of ES2763563T3 publication Critical patent/ES2763563T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00—Methods of screening libraries
    • C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00—Labels used in chemical analysis of biological material
    • G01N2458/10—Oligonucleotides as tagging agents for labelling antibodies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
ES15816204T 2014-11-24 2015-11-24 Método Active ES2763563T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1420852.4A GB201420852D0 (en) 2014-11-24 2014-11-24 Method
PCT/GB2015/053573 WO2016083793A1 (en) 2014-11-24 2015-11-24 Method

Publications (1)

Publication Number Publication Date
ES2763563T3 true ES2763563T3 (es) 2020-05-29

Family

ID=52292436

Family Applications (1)

Application Number Title Priority Date Filing Date
ES15816204T Active ES2763563T3 (es) 2014-11-24 2015-11-24 Método

Country Status (10)

Country Link
US (3) US10605814B2 (enExample)
EP (1) EP3224360B1 (enExample)
JP (1) JP6871168B2 (enExample)
KR (1) KR102422494B1 (enExample)
CN (1) CN107430130B (enExample)
CA (1) CA2968488C (enExample)
ES (1) ES2763563T3 (enExample)
GB (1) GB201420852D0 (enExample)
SG (2) SG10202008300RA (enExample)
WO (1) WO2016083793A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017214211A1 (en) * 2016-06-09 2017-12-14 Igc Bio, Inc. Methods for identifying a high affinity antibody
EP3577258B1 (en) * 2017-01-31 2024-11-27 48Hour Discovery Inc. Display of molecules on silently genetically encoded nanoscale carriers for determining synergistic molecular interactions
US20200355685A1 (en) * 2017-11-06 2020-11-12 Tsinghua University Reagent set for detecting interactions between biomolecules and their regulatory factors, and applications
US12391939B2 (en) 2018-07-23 2025-08-19 The Governors Of The University Of Alberta Genetically-encoded bicyclic peptide libraries
EP4245862B1 (en) 2019-06-25 2025-01-15 Actome GmbH Method and kit for measuring of analytes in bi-component systems and uses thereof
JP7727628B2 (ja) 2019-12-03 2025-08-21 アラマー バイオサイエンシーズ， インク． 核酸結合免疫サンドイッチアッセイ（ｎｕｌｉｓａ）
EP4330678A1 (en) * 2021-04-26 2024-03-06 Ecole Polytechnique Federale De Lausanne (Epfl) High complexity microcompartment-based interaction screening
US12704508B2 (en) 2021-06-02 2026-08-11 Alamar Biosciences, Inc. Nucleic acid linked immune-sandwich assay (NULISA)
EP4242656A1 (en) * 2022-03-10 2023-09-13 Actome GmbH Quantitative detection method and corresponding device
CN119698486A (zh) 2022-06-29 2025-03-25 阿克托姆有限责任公司 检测单细胞中的生物分子
GB202218453D0 (en) 2022-12-08 2023-01-25 Actome Gmbh Assay system

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8308235D0 (en) 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
ATE199392T1 (de) 1992-12-04 2001-03-15 Medical Res Council Multivalente und multispezifische bindungsproteine, deren herstellung und verwendung
US7306904B2 (en) 2000-02-18 2007-12-11 Olink Ab Methods and kits for proximity probing
GB0422431D0 (en) * 2004-10-08 2004-11-10 Affitech As Method
ES2448426T3 (es) * 2007-10-12 2014-03-13 Pronota Nv Uso de aptámeros en proteómica
GB0903316D0 (en) * 2009-02-26 2009-04-08 Affitech As Method
AU2010249470B2 (en) 2009-05-20 2015-06-25 Novimmune S.A. Synthetic Polypeptide Libraries And Methods For Generating Naturally Diversified Polypeptide Variants
EP2452195A4 (en) * 2009-07-07 2012-12-05 Agency Science Tech & Res METHOD FOR IDENTIFYING A PAIR OF CONNECTING PARTNERS
CN103119165B (zh) * 2010-09-27 2017-04-12 威泊根私人有限公司 制备富集文库的方法
US9209965B2 (en) 2014-01-14 2015-12-08 Microsemi Semiconductor Ulc Network interface with clock recovery module on line card

Also Published As

Publication number Publication date
US11421347B2 (en) 2022-08-23
CN107430130B (zh) 2020-07-24
CA2968488C (en) 2024-09-10
US10605814B2 (en) 2020-03-31
EP3224360A1 (en) 2017-10-04
SG10202008300RA (en) 2020-10-29
KR102422494B1 (ko) 2022-07-19
US20210003585A1 (en) 2021-01-07
US20230175171A1 (en) 2023-06-08
CN107430130A (zh) 2017-12-01
SG11201703689SA (en) 2017-06-29
JP2017536846A (ja) 2017-12-14
EP3224360B1 (en) 2019-10-09
WO2016083793A1 (en) 2016-06-02
JP6871168B2 (ja) 2021-05-12
US20170269098A1 (en) 2017-09-21
KR20170086627A (ko) 2017-07-26
CA2968488A1 (en) 2016-06-02
GB201420852D0 (en) 2015-01-07

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