ES2753381T3 - Miméticos de apolipoproteína y usos de los mismos - Google Patents

Miméticos de apolipoproteína y usos de los mismos Download PDF

Info

Publication number
ES2753381T3
ES2753381T3 ES14769489T ES14769489T ES2753381T3 ES 2753381 T3 ES2753381 T3 ES 2753381T3 ES 14769489 T ES14769489 T ES 14769489T ES 14769489 T ES14769489 T ES 14769489T ES 2753381 T3 ES2753381 T3 ES 2753381T3
Authority
ES
Spain
Prior art keywords
apo
peptide
seq
mimetic
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES14769489T
Other languages
English (en)
Spanish (es)
Inventor
Gattadahalli M Anantharamaiah
Dennis Goldberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UAB Research Foundation
LipimetiX Development LLC
Original Assignee
UAB Research Foundation
LipimetiX Development LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UAB Research Foundation, LipimetiX Development LLC filed Critical UAB Research Foundation
Application granted granted Critical
Publication of ES2753381T3 publication Critical patent/ES2753381T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/775—Apolipopeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
ES14769489T 2013-03-14 2014-03-14 Miméticos de apolipoproteína y usos de los mismos Active ES2753381T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361782956P 2013-03-14 2013-03-14
US201361834992P 2013-06-14 2013-06-14
PCT/US2014/027719 WO2014152776A1 (en) 2013-03-14 2014-03-14 Apolipoprotein mimetics and uses thereof

Publications (1)

Publication Number Publication Date
ES2753381T3 true ES2753381T3 (es) 2020-04-08

Family

ID=51581312

Family Applications (1)

Application Number Title Priority Date Filing Date
ES14769489T Active ES2753381T3 (es) 2013-03-14 2014-03-14 Miméticos de apolipoproteína y usos de los mismos

Country Status (12)

Country Link
US (1) US20160002315A1 (https=)
EP (1) EP2996706B1 (https=)
JP (2) JP6570511B2 (https=)
AU (2) AU2014239186B2 (https=)
BR (1) BR112015022624A2 (https=)
CA (1) CA2903869A1 (https=)
DK (1) DK2996706T3 (https=)
ES (1) ES2753381T3 (https=)
IL (1) IL240787B (https=)
MX (1) MX2015012818A (https=)
NZ (1) NZ713291A (https=)
WO (1) WO2014152776A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX383117B (es) 2014-07-31 2025-03-13 Anji Pharmaceuticals Inc Péptidos miméticos de la apoe y mayor potencia para depurar el colesterol en plasma.
WO2017120568A1 (en) * 2016-01-08 2017-07-13 Lipimetix Development, Inc. Apoe mimetic peptide compositions
PL3416684T3 (pl) * 2016-02-17 2023-11-06 Regeneron Pharmaceuticals, Inc. Sposoby leczenia lub profilaktyki miażdżycy tętnic przez podawanie inhibitora angptl3
JP7541810B2 (ja) 2016-03-03 2024-08-29 リジェネロン・ファーマシューティカルズ・インコーポレイテッド Ａｎｇｐｔｌ３阻害剤と組み合わせてｐｃｓｋ９阻害剤を投与することにより高脂血症を有する患者を処置するための方法
US12559551B2 (en) 2019-05-24 2026-02-24 Regeneron Pharmaceuticals, Inc. Stabilized formulations containing anti-ANGPTL3 antibodies
WO2023018876A2 (en) * 2021-08-11 2023-02-16 The Regents Of The University Of California Barrier function preserving peptides for membranes

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO812612L (no) 1980-08-06 1982-02-08 Ferring Pharma Ltd Enzym-inhibitorer.
GB9022788D0 (en) 1990-10-19 1990-12-05 Cortecs Ltd Pharmaceutical formulations
US5331573A (en) 1990-12-14 1994-07-19 Balaji Vitukudi N Method of design of compounds that mimic conformational features of selected peptides
US5631280A (en) 1995-03-29 1997-05-20 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
US6506880B2 (en) 1998-03-17 2003-01-14 The Uab Research Foundation Synthetic peptides that enhance atherogenic lipoprotein uptake and lower plasma cholesterol
US6664230B1 (en) 2000-08-24 2003-12-16 The Regents Of The University Of California Orally administered peptides to ameliorate atherosclerosis
US7199102B2 (en) 2000-08-24 2007-04-03 The Regents Of The University Of California Orally administered peptides synergize statin activity
US8557767B2 (en) * 2007-08-28 2013-10-15 Uab Research Foundation Synthetic apolipoprotein E mimicking polypeptides and methods of use
US20130005645A1 (en) * 2010-01-06 2013-01-03 Vitek Michael P Apoe peptide dimers and uses thereof
MX383117B (es) * 2014-07-31 2025-03-13 Anji Pharmaceuticals Inc Péptidos miméticos de la apoe y mayor potencia para depurar el colesterol en plasma.

Also Published As

Publication number Publication date
EP2996706A4 (en) 2017-01-18
BR112015022624A2 (pt) 2017-10-31
IL240787A0 (en) 2015-10-29
JP2019089834A (ja) 2019-06-13
AU2017203911B2 (en) 2019-03-07
AU2014239186A1 (en) 2015-10-08
JP6570511B2 (ja) 2019-09-04
EP2996706A1 (en) 2016-03-23
JP6772317B2 (ja) 2020-10-21
NZ713291A (en) 2017-04-28
AU2014239186B2 (en) 2017-04-20
EP2996706B1 (en) 2019-07-31
IL240787B (en) 2019-07-31
US20160002315A1 (en) 2016-01-07
WO2014152776A1 (en) 2014-09-25
MX2015012818A (es) 2016-05-12
JP2016515137A (ja) 2016-05-26
DK2996706T3 (da) 2019-10-21
CA2903869A1 (en) 2014-09-25
AU2017203911A1 (en) 2017-06-29

Similar Documents

Publication Publication Date Title
JP7095037B2 (ja) アポｅ模倣ペプチド及び血漿コレステロールを取り除くためのより高い効果
ES2342258T3 (es) Peptidos administrados oralmente para mejorar la aterosclerosis.
JP6772317B2 (ja) アポリポタンパク質模倣体及びその使用
US20210324043A1 (en) ApoC-II Mimetic Peptides
JP2007534612A (ja) 高コレステロール血症の治療のためのコレステロール逆輸送メディエータ
RU2820132C2 (ru) Способ улучшения симптомов со стороны нижних мочевыводящих путей
CN107106639A (zh) 合成肽
JP2025160231A (ja) 下部尿路症状を改善する方法
HK1242718A1 (en) Apoe mimetic peptides and higher potency to clear plasma cholesterol
EA042134B1 (ru) МИМЕТИЧЕСКИЕ ПЕПТИДЫ apoC-II
HK1242718B (zh) Apoe模拟肽及对清除血浆胆固醇的较高效力