ES2752063T3 - Administración intrapulmonar de agonistas polinucleotídicos del receptor de tipo toll 9 para el tratamiento del cáncer de pulmón - Google Patents
Administración intrapulmonar de agonistas polinucleotídicos del receptor de tipo toll 9 para el tratamiento del cáncer de pulmón Download PDFInfo
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- ES2752063T3 ES2752063T3 ES16727089T ES16727089T ES2752063T3 ES 2752063 T3 ES2752063 T3 ES 2752063T3 ES 16727089 T ES16727089 T ES 16727089T ES 16727089 T ES16727089 T ES 16727089T ES 2752063 T3 ES2752063 T3 ES 2752063T3
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- polynucleotide
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| EP4029508A1 (en) | 2014-10-10 | 2022-07-20 | Idera Pharmaceuticals, Inc. | Treatment of cancer using tlr9 agonists and checkpoint inhibitors |
| AU2015349680A1 (en) | 2014-11-21 | 2017-06-08 | Northwestern University | The sequence-specific cellular uptake of spherical nucleic acid nanoparticle conjugates |
| KR102779525B1 (ko) | 2015-05-29 | 2025-03-12 | 다이나박스 테크놀로지 코퍼레이션 | 폐암을 치료하기 위한 폴리뉴클레오티드 Toll-유사 수용체 9 아고니스트의 폐내 투여 |
| US11364304B2 (en) | 2016-08-25 | 2022-06-21 | Northwestern University | Crosslinked micellar spherical nucleic acids |
| US10463686B2 (en) | 2016-09-15 | 2019-11-05 | Idera Pharmaceuticals, Inc. | Immune modulation with TLR9 agonists for cancer treatment |
| WO2018209270A1 (en) | 2017-05-11 | 2018-11-15 | Northwestern University | Adoptive cell therapy using spherical nucleic acids (snas) |
| WO2020081398A1 (en) * | 2018-10-14 | 2020-04-23 | Dynavax Technologies Corporation | Combination including a cpg-c type oligonucleotide and a pd-1 antagonist for treating breast cancer |
| WO2020079185A1 (en) * | 2018-10-18 | 2020-04-23 | Deutsches Krebsforschungszentrum | Dry pharmaceutical composition for inhalation |
| CN111321159B (zh) * | 2018-12-14 | 2023-12-12 | 中天(上海)生物科技有限公司 | 用于免疫调节的嵌合核酸分子及其应用 |
| WO2020128893A1 (en) * | 2018-12-21 | 2020-06-25 | Pfizer Inc. | Combination treatments of cancer comprising a tlr agonist |
| WO2021007160A1 (en) | 2019-07-05 | 2021-01-14 | Tambo, Inc. | Trans-cyclooctene bioorthogonal agents and uses in cancer and immunotherapy |
| US11613755B2 (en) * | 2019-12-31 | 2023-03-28 | Industrial Technology Research Institute | Nucleic acid-drug complex and use thereof |
| EP4192506A1 (en) | 2020-08-07 | 2023-06-14 | Tambo, Inc. | Trans-cyclooctene bioorthogonal agents and uses in cancer and immunotherapy |
| CN114099535B (zh) * | 2020-12-10 | 2023-01-03 | 南京吉迈生物技术有限公司 | Toll样受体9(TLR9)激动剂水凝胶免疫调节组合物 |
| US20240139175A1 (en) * | 2020-12-23 | 2024-05-02 | Cascade Prodrug Inc. | Combination therapy with a vinca alkaloid n-oxide and an immune checkpoint inhibitor |
| WO2023081486A1 (en) | 2021-11-08 | 2023-05-11 | Nurix Therapeutics, Inc. | Toll-like receptor therapy combinations with cbl-b inhibitor compounds |
| AU2023209887A1 (en) * | 2022-01-21 | 2024-08-15 | Trisalus Life Sciences, Inc. | Methods of treating immune dysfunction in liver cancer with toll-like receptor agonists |
| WO2024186193A1 (ko) * | 2023-03-08 | 2024-09-12 | 인제대학교 산학협력단 | 국소적 방사선 치료에서 전신성 항암 치료를 위한 조성물 |
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| CA2323929C (en) * | 1998-04-03 | 2004-03-09 | University Of Iowa Research Foundation | Methods and products for stimulating the immune system using immunotherapeutic oligonucleotides and cytokines |
| WO1999060166A1 (en) * | 1998-05-21 | 1999-11-25 | Isis Pharmaceuticals, Inc. | Compositions and methods for the pulmonary delivery of nucleic acids |
| CN1293192C (zh) | 2000-12-27 | 2007-01-03 | 戴纳瓦克斯技术公司 | 免疫调节性多核苷酸及其使用方法 |
| TW200303759A (en) * | 2001-11-27 | 2003-09-16 | Schering Corp | Methods for treating cancer |
| ES2350687T3 (es) * | 2002-07-03 | 2011-01-26 | Ono Pharmaceutical Co., Ltd. | Composiciones de inmunopotenciación. |
| US8158768B2 (en) * | 2002-12-23 | 2012-04-17 | Dynavax Technologies Corporation | Immunostimulatory sequence oligonucleotides and methods of using the same |
| SG2011035342A (en) * | 2002-12-23 | 2016-12-29 | Dynavax Tech Corp | Immunostimulatory sequence oligonucleotides and methods of using the same |
| TW200533750A (en) * | 2004-02-19 | 2005-10-16 | Coley Pharm Group Inc | Immunostimulatory viral RNA oligonucleotides |
| CN101134046B (zh) * | 2006-09-01 | 2011-10-05 | 中国医学科学院药物研究所 | Tlr4和tlr9激动剂复方在抑制肿瘤转移中的应用 |
| CA2750499A1 (en) * | 2009-01-30 | 2010-08-05 | Idera Pharmaceuticals, Inc. | Novel synthetic agonists of tlr9 |
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| EP3065772B1 (en) * | 2013-11-05 | 2024-07-24 | Cognate Bioservices, Inc. | Combinations of checkpoint inhibitors and therapeutics to treat cancer |
| CA2986232A1 (en) * | 2015-05-29 | 2016-12-08 | Merck Sharp & Dohme Corp. | Combination of an anti-il-10 antibody and a cpg-c type oligonucleotide for treating cancer |
| KR102779525B1 (ko) | 2015-05-29 | 2025-03-12 | 다이나박스 테크놀로지 코퍼레이션 | 폐암을 치료하기 위한 폴리뉴클레오티드 Toll-유사 수용체 9 아고니스트의 폐내 투여 |
| JP2019515900A (ja) * | 2016-04-15 | 2019-06-13 | ダイナバックス テクノロジーズ コーポレイション | がんを処置するためのＴｏｌｌ様レセプター９アゴニストおよび腫瘍抗原を含む粒子の腫瘍内送達 |
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| EP3302502A1 (en) | 2018-04-11 |
| US20160346312A1 (en) | 2016-12-01 |
| US10111899B2 (en) | 2018-10-30 |
| HK1251471A1 (zh) | 2019-02-01 |
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| AU2016270782B2 (en) | 2021-08-12 |
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| KR20180021700A (ko) | 2018-03-05 |
| EP3590518B1 (en) | 2024-03-20 |
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| EP3590518A1 (en) | 2020-01-08 |
| EP3302502B1 (en) | 2019-08-28 |
| JP6792294B2 (ja) | 2020-11-25 |
| RU2017145940A3 (enExample) | 2019-11-26 |
| US20190151345A1 (en) | 2019-05-23 |
| US20180264023A1 (en) | 2018-09-20 |
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| US9993495B2 (en) | 2018-06-12 |
| AU2016270782A1 (en) | 2017-12-07 |
| WO2016196062A1 (en) | 2016-12-08 |
| IL255903A (en) | 2018-01-31 |
| MX2017015294A (es) | 2018-02-19 |
| IL255903B (en) | 2021-09-30 |
| RU2017145940A (ru) | 2019-07-02 |
| MX381587B (es) | 2025-03-12 |
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