ES2712666T3 - Dispositivo - Google Patents
Dispositivo Download PDFInfo
- Publication number
- ES2712666T3 ES2712666T3 ES10778710T ES10778710T ES2712666T3 ES 2712666 T3 ES2712666 T3 ES 2712666T3 ES 10778710 T ES10778710 T ES 10778710T ES 10778710 T ES10778710 T ES 10778710T ES 2712666 T3 ES2712666 T3 ES 2712666T3
- Authority
- ES
- Spain
- Prior art keywords
- well
- diluent
- nucleic acid
- channel
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/16—Reagents, handling or storing thereof
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/041—Connecting closures to device or container
- B01L2300/042—Caps; Plugs
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/046—Function or devices integrated in the closure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/087—Multiple sequential chambers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5023—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures with a sample being transported to, and subsequently stored in an absorbent for analysis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
- B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
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| PCT/GB2010/051832 WO2011051735A2 (en) | 2009-11-02 | 2010-11-02 | Device and apparatus |
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| ES2712666T3 true ES2712666T3 (es) | 2019-05-14 |
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| TR (1) | TR201900390T4 (enExample) |
| WO (1) | WO2011051735A2 (enExample) |
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| US9423398B2 (en) * | 2011-02-08 | 2016-08-23 | The Board Of Regents For Oklahoma State University | Apparatus and method for biologic sample rapid collection and recovery device, and convenient storage |
| WO2014081460A1 (en) * | 2012-11-20 | 2014-05-30 | Kisner Mark | Chemical sequencing and control to expand and enhance detection capabilities utilizing a colorimetric test |
| EP2925448B1 (en) | 2012-12-03 | 2019-05-22 | The Secretary of State for Environment, Food and Rural Affairs | Device and method for carrying out an assay to detect a nucleic acid in a sample |
| EP2932266A4 (en) | 2012-12-17 | 2016-11-30 | Leukodx Ltd | SYSTEMS AND METHOD FOR DETERMINING A CHEMICAL CONDITION |
| US20140170678A1 (en) * | 2012-12-17 | 2014-06-19 | Leukodx Ltd. | Kits, compositions and methods for detecting a biological condition |
| EP2948249A1 (en) | 2013-01-22 | 2015-12-02 | University of Washington through its Center for Commercialization | Sequential delivery of fluid volumes and associated devices, systems and methods |
| DK2821138T4 (da) | 2013-07-05 | 2022-05-16 | Thinxxs Microtechnology Gmbh | Flydecelle med integreret tørstof |
| US10946376B2 (en) | 2013-07-05 | 2021-03-16 | Thinxxs Microtechnology Ag | Carrier element for introducing a dry substance into a flow cell |
| KR101398764B1 (ko) * | 2013-08-29 | 2014-05-27 | 강릉원주대학교산학협력단 | 입자의 이동에 의해 분석물질을 검출하는 장치 및 방법 |
| HK1222597A1 (zh) * | 2013-10-22 | 2017-07-07 | 艾博生物医药(杭州)有限公司 | 用於检测液体样本中的分析物的检测装置 |
| EP3089823A4 (en) * | 2013-12-31 | 2017-12-20 | Canon U.S. Life Sciences, Inc. | Field deployable small format fast first result microfluidic system |
| BR112017005121A2 (pt) * | 2014-09-23 | 2018-07-31 | Tearlab Res Inc | sistemas e métodos para integração de coleta de lágrima microfluídica e análise de fluxo lateral de analitos de interesse. |
| FR3032719B1 (fr) * | 2015-02-13 | 2020-05-15 | Centre National De La Recherche Scientifique | Dispositif de diagnostic par amplification isotherme d'adn |
| WO2016163946A1 (en) * | 2015-04-07 | 2016-10-13 | Cell Id Pte Ltd | A dc heater |
| US10775370B2 (en) | 2015-07-17 | 2020-09-15 | Stat-Diagnostica & Innovation, S.L. | Fluidic system for performing assays |
| GB201611442D0 (en) * | 2016-06-30 | 2016-08-17 | Lumiradx Tech Ltd | Fluid control |
| CN109477835B (zh) * | 2016-07-25 | 2022-08-16 | 生物辐射实验室股份有限公司 | 侧流装置及使用方法 |
| GB201616718D0 (en) * | 2016-09-30 | 2016-11-16 | Microbiosensor Limited | Microbial sensing devices |
| GB201700340D0 (en) | 2017-01-09 | 2017-02-22 | Gsg Tech Ltd | fluid manipulation cartridge and controller mechanism |
| GB201715704D0 (en) * | 2017-09-28 | 2017-11-15 | Microbiosensor Ltd | Methods and devices |
| FR3075823A1 (fr) * | 2017-12-21 | 2019-06-28 | Nanobiose | Procede d’analyse d’un echantillon cellulaire au moyen d’un laboratoire sur puce-micro-fluidique |
| FR3075817B1 (fr) * | 2017-12-21 | 2020-12-25 | Nanobiose | Puce micro-fluidique et laboratoire sur puce-micro-fluidique |
| EP3728556A1 (fr) * | 2017-12-21 | 2020-10-28 | Nanobiose | Puce micro-fluidique, laboratoire sur puce micro-fluidique, procédé de fabrication d'une telle puce et procédé d'analyse |
| US10046322B1 (en) * | 2018-03-22 | 2018-08-14 | Talis Biomedical Corporation | Reaction well for assay device |
| AU2019397371B2 (en) * | 2018-12-10 | 2025-09-18 | Combinati Incorporated | Microfluidic array for sample digitization |
| CN110358665A (zh) * | 2019-06-28 | 2019-10-22 | 马鞍山众慧惠生生物科技有限公司 | 箱式集成化核酸定量检测装置 |
| US11008627B2 (en) | 2019-08-15 | 2021-05-18 | Talis Biomedical Corporation | Diagnostic system |
| JP7164505B2 (ja) * | 2019-10-02 | 2022-11-01 | 積水化学工業株式会社 | マイクロ流路チップ |
| WO2021231607A1 (en) * | 2020-05-12 | 2021-11-18 | Godx, Inc. | Point of need diagnostic device and methods of use thereof |
| WO2021236850A1 (en) * | 2020-05-19 | 2021-11-25 | Mammoth Biosciences, Inc. | Devices, assays and methods for detection of nucleic acids |
| JPWO2022030605A1 (enExample) * | 2020-08-07 | 2022-02-10 | ||
| US11567071B2 (en) | 2020-10-16 | 2023-01-31 | Fresenius Medical Care Holdings, Inc. | Devices and methods for lateral flow tests of bodily fluids |
| EP4173708A1 (de) * | 2021-10-28 | 2023-05-03 | thinXXS Microtechnology GmbH | Mikrofluidelement, insbesondere flusszelle, mit integriertem trockenreagenz |
| CA3247043A1 (en) * | 2022-04-15 | 2023-10-19 | Siemens Healthcare Diagnostics Inc | CREATININE SIDE-FLOW TESTING DEVICES AND METHODS OF MANUFACTURE AND USE |
| WO2024127334A2 (en) * | 2022-12-16 | 2024-06-20 | 3M Innovative Properties Company | Sample collection and analysis system |
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| US7465562B2 (en) * | 2003-05-19 | 2008-12-16 | Brandeis University | Nucleic acid processing methods, kits and devices |
| EP1735618A2 (en) | 2004-02-27 | 2006-12-27 | Board of Regents, The University of Texas System | System and method for integrating fluids and reagents in self-contained cartridges containing particle and membrane sensor elements |
| US20050227275A1 (en) * | 2004-04-07 | 2005-10-13 | Access Bio, Inc. | Nucleic acid detection system |
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| CN101258397B (zh) | 2005-07-14 | 2012-07-04 | 毫微创新科技公司 | 微流装置和制备及使用方法 |
| WO2007092713A2 (en) * | 2006-02-02 | 2007-08-16 | Trustees Of The University Of Pennsylvania | Microfluidic system and method for analysis of gene expression in cell-containing samples and detection of disease |
| WO2007098184A2 (en) * | 2006-02-21 | 2007-08-30 | Nanogen, Inc. | Methods and compositions for analyte detection |
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| US8691592B2 (en) * | 2006-12-14 | 2014-04-08 | The Trustees Of The University Of Pennsylvania | Mechanically actuated diagnostic device |
| WO2008103824A1 (en) | 2007-02-23 | 2008-08-28 | Chinese Academy Of Inspection And Quarantine (Caiq) | Sensitivity-enhanced dot-antibody linked immunogold assay for virus detection |
| GB2453356A (en) | 2007-10-03 | 2009-04-08 | James Homrig | Assay device comprising control analytes to confirm assay completion |
| US8911938B2 (en) * | 2007-12-10 | 2014-12-16 | The Trustees Of The University Of Pennsylvania | Reaction chamber having pre-stored reagents |
| DE102007062441A1 (de) * | 2007-12-20 | 2009-06-25 | Aj Innuscreen Gmbh | Mobiles Schnelltestsystem für die Nukleinsäureanalytik |
| JP5049404B2 (ja) * | 2008-03-31 | 2012-10-17 | エージェンシー フォー サイエンス, テクノロジー アンド リサーチ | 相互接続マルチチャンバデバイスを使用する流体処理および移送の方法 |
| US8697007B2 (en) * | 2008-08-06 | 2014-04-15 | The Trustees Of The University Of Pennsylvania | Biodetection cassette with automated actuator |
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Also Published As
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| EP2496351A2 (en) | 2012-09-12 |
| CN102655938B (zh) | 2014-09-17 |
| TR201900390T4 (tr) | 2019-02-21 |
| JP2013509173A (ja) | 2013-03-14 |
| US9163279B2 (en) | 2015-10-20 |
| WO2011051735A2 (en) | 2011-05-05 |
| CA2778329A1 (en) | 2011-05-05 |
| EP2496351B1 (en) | 2019-01-02 |
| AU2010311138A1 (en) | 2012-05-03 |
| AU2010311138B2 (en) | 2014-08-28 |
| US20120270225A1 (en) | 2012-10-25 |
| CA2778329C (en) | 2018-09-04 |
| JP5934100B2 (ja) | 2016-06-15 |
| GB0919159D0 (en) | 2009-12-16 |
| CN102655938A (zh) | 2012-09-05 |
| WO2011051735A3 (en) | 2011-08-18 |
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