ES2708087T3 - Procedimientos y composiciones para tratar enfermedad inflamatoria intestinal - Google Patents

Procedimientos y composiciones para tratar enfermedad inflamatoria intestinal Download PDF

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Publication number
ES2708087T3
ES2708087T3 ES09708397T ES09708397T ES2708087T3 ES 2708087 T3 ES2708087 T3 ES 2708087T3 ES 09708397 T ES09708397 T ES 09708397T ES 09708397 T ES09708397 T ES 09708397T ES 2708087 T3 ES2708087 T3 ES 2708087T3
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Spain
Prior art keywords
rifabutin
clofazimine
clarithromycin
abc
peg
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES09708397T
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English (en)
Spanish (es)
Inventor
Thomas Julius Borody
Patrick Gosselin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RED HILL BIOPHARMA Ltd
Original Assignee
RED HILL BIOPHARMA Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by RED HILL BIOPHARMA Ltd filed Critical RED HILL BIOPHARMA Ltd
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Publication of ES2708087T3 publication Critical patent/ES2708087T3/es
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/438The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ES09708397T 2008-02-08 2009-02-05 Procedimientos y composiciones para tratar enfermedad inflamatoria intestinal Active ES2708087T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6514408P 2008-02-08 2008-02-08
PCT/AU2009/000129 WO2009097651A1 (en) 2008-02-08 2009-02-05 Methods and compositions for treating inflammatory bowel disease

Publications (1)

Publication Number Publication Date
ES2708087T3 true ES2708087T3 (es) 2019-04-08

Family

ID=40951740

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09708397T Active ES2708087T3 (es) 2008-02-08 2009-02-05 Procedimientos y composiciones para tratar enfermedad inflamatoria intestinal

Country Status (18)

Country Link
US (10) US8343511B2 (enExample)
EP (2) EP2247291B1 (enExample)
JP (1) JP5572872B2 (enExample)
AU (1) AU2009212097B2 (enExample)
CA (1) CA2714043C (enExample)
CY (1) CY1121465T1 (enExample)
DK (1) DK2247291T3 (enExample)
ES (1) ES2708087T3 (enExample)
HR (1) HRP20190045T1 (enExample)
HU (1) HUE041305T2 (enExample)
IL (1) IL207420A (enExample)
NZ (1) NZ587250A (enExample)
PL (1) PL2247291T3 (enExample)
PT (1) PT2247291T (enExample)
SI (1) SI2247291T1 (enExample)
TR (1) TR201819940T4 (enExample)
WO (1) WO2009097651A1 (enExample)
ZA (1) ZA201005735B (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ587250A (en) 2008-02-08 2011-12-22 Red Hill Biopharma Ltd Methods and compositions for treating inflammatory bowel disease
TWI573590B (zh) * 2011-09-20 2017-03-11 雷希爾生藥有限公司 治療自體免疫疾病之組成物及方法
CA2883443C (en) 2012-08-30 2021-01-12 James Sacchettini Compositions and methods for drug-sensitization or inhibition of a cancer cell
WO2015123392A1 (en) * 2014-02-14 2015-08-20 The Texas A&M University System Compositions and methods for inhibition of angiogenesis and lymphangiogenesis
EP3145510B8 (en) * 2014-05-22 2021-10-27 Kuenstner, John, Todd Treatment of diseases using combination of ultraviolet blood irradiation and antibiotics
EP3291798A4 (en) * 2015-05-04 2019-01-16 Gufic Biosciences Limited LYOPHILIZED PHARMACEUTICAL FORMULATION OF RIFABUTIN AND PREPARATION METHOD THEREOF
BR112018003232A2 (pt) * 2015-10-06 2018-09-25 Redhill Biopharma Ltd terapias de combinação para tratamento de câncer
CN107202848B (zh) * 2017-07-24 2022-11-15 浙江华海药业股份有限公司 一种氯法齐明的液相色谱分析方法
EP3676580A4 (en) * 2017-08-29 2021-05-26 Weightrx Inc. SYSTEM AND PROCESS FOR AUTOMATED MONITORING OF CONSUMABLES
AU2020344214A1 (en) * 2019-09-12 2022-04-21 BioVersys AG Antibiotic combination therapies
CA3187031A1 (en) * 2020-06-30 2022-01-06 Redhill Biopharma Ltd. Triple antibiotic fixed-dose combination products, dosing regimen, methods, and kits for treating pulmonary non-tuberculosis mycobacterial infections
WO2022204375A1 (en) * 2021-03-25 2022-09-29 The Regents Of The University Of Michigan Compositions and methods for detecting, preventing, and treating disturbed microbiota-immune homeostasis

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5840733A (en) 1996-07-01 1998-11-24 Redcell, Canada, Inc. Methods and compositions for producing novel conjugates of thrombin inhibitors and endogenous carriers resulting in anti-thrombins with extended lifetimes
DE69839261T2 (de) * 1997-04-01 2009-03-26 Borody, Thomas Julius, Five Dock Verfahren und zusammensetzungen zur behandlung entzündlicher darmerkrankungen
US6761903B2 (en) * 1999-06-30 2004-07-13 Lipocine, Inc. Clear oil-containing pharmaceutical compositions containing a therapeutic agent
NZ587250A (en) 2008-02-08 2011-12-22 Red Hill Biopharma Ltd Methods and compositions for treating inflammatory bowel disease

Also Published As

Publication number Publication date
SI2247291T1 (sl) 2019-03-29
TR201819940T4 (tr) 2019-01-21
PL2247291T3 (pl) 2019-05-31
CA2714043A1 (en) 2009-08-13
US20140315841A1 (en) 2014-10-23
NZ587250A (en) 2011-12-22
US20110059136A1 (en) 2011-03-10
CA2714043C (en) 2016-11-08
US10765691B2 (en) 2020-09-08
US20200030352A1 (en) 2020-01-30
HUE041305T2 (hu) 2019-05-28
IL207420A0 (en) 2010-12-30
US20170232028A1 (en) 2017-08-17
ZA201005735B (en) 2011-10-26
CY1121465T1 (el) 2020-05-29
US9314477B2 (en) 2016-04-19
EP3391882A1 (en) 2018-10-24
US11090326B2 (en) 2021-08-17
IL207420A (en) 2015-09-24
DK2247291T3 (en) 2019-01-21
US20130237488A1 (en) 2013-09-12
US20200206253A1 (en) 2020-07-02
EP2247291A4 (en) 2011-04-13
AU2009212097B2 (en) 2013-06-13
US9072763B2 (en) 2015-07-07
US20190060343A1 (en) 2019-02-28
HRP20190045T1 (hr) 2019-03-08
US10434114B2 (en) 2019-10-08
WO2009097651A1 (en) 2009-08-13
US9198926B2 (en) 2015-12-01
US10143702B2 (en) 2018-12-04
EP2247291A1 (en) 2010-11-10
JP2011511012A (ja) 2011-04-07
US10105379B2 (en) 2018-10-23
AU2009212097A1 (en) 2009-08-13
US20140243279A1 (en) 2014-08-28
PT2247291T (pt) 2019-02-01
EP2247291B1 (en) 2018-12-05
US20160228464A1 (en) 2016-08-11
US20180125872A1 (en) 2018-05-10
US8343511B2 (en) 2013-01-01
JP5572872B2 (ja) 2014-08-20

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