ES2700473T3 - Biodisponibilidad cerebral mejorada de galantamina mediante formulaciones seleccionadas y administración transmucosa de profármacos lipofílicos - Google Patents
Biodisponibilidad cerebral mejorada de galantamina mediante formulaciones seleccionadas y administración transmucosa de profármacos lipofílicos Download PDFInfo
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- ES2700473T3 ES2700473T3 ES13745810T ES13745810T ES2700473T3 ES 2700473 T3 ES2700473 T3 ES 2700473T3 ES 13745810 T ES13745810 T ES 13745810T ES 13745810 T ES13745810 T ES 13745810T ES 2700473 T3 ES2700473 T3 ES 2700473T3
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Applications Claiming Priority (3)
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| US201261676348P | 2012-07-27 | 2012-07-27 | |
| EP12178187 | 2012-07-27 | ||
| PCT/EP2013/065880 WO2014016430A1 (en) | 2012-07-27 | 2013-07-29 | Enhanced brain bioavailability of galantamine by selected formulations and transmucosal administration of lipophilic prodrugs |
Publications (1)
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| ES2700473T3 true ES2700473T3 (es) | 2019-02-18 |
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| EP (2) | EP3417862B1 (enExample) |
| JP (2) | JP6272857B2 (enExample) |
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Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US20090253654A1 (en) | 2005-09-22 | 2009-10-08 | Galantos Pharma Gmbh | Cholinergic enhancers with improved blood-brain barrier permeability for the treatment of diseases accompanied by cognitive impairment |
| PT3417862T (pt) * | 2012-07-27 | 2021-08-06 | Neurodyn Life Sciences Inc | Biodisponibilidade cerebral da galantamina melhorada através de formulações selecionadas e administração transmucosal de pró-fármacos lipofílicos |
| EP3142669A2 (en) | 2014-05-16 | 2017-03-22 | Synaptec Development LLC | CLEARANCE OF AMYLOID ß |
| JP2020033304A (ja) * | 2018-08-30 | 2020-03-05 | 医療法人ふじいやさか | 薬剤又はサプリメント、組成物、及び水素供給器の使用 |
| CN114828848A (zh) * | 2019-06-28 | 2022-07-29 | 宾夕法尼亚大学理事会 | 用于治疗阿尔茨海默氏病的鼻内丹曲林施用 |
| EP4029867A1 (en) * | 2021-01-13 | 2022-07-20 | Alpha Cognition Inc. | Solid forms of galantamine benzoate gluconate |
| CN117279646A (zh) * | 2021-05-14 | 2023-12-22 | 阿尔法认知公司 | 用于给药α-1062的自防腐组合物和多次使用分配器 |
| EP4186509A1 (en) | 2021-11-26 | 2023-05-31 | Alpha Cognition Inc. | Alpha-1062 for treating traumatic brain injury |
| JP2024541507A (ja) * | 2021-11-26 | 2024-11-08 | アルファ コグニション インコーポレイティド | 外傷性脳損傷を治療するためのａｌｐｈａ－１０６２ |
| WO2024239120A1 (en) * | 2023-05-25 | 2024-11-28 | Alpha Cognition Inc. | Benzgalantamine for treating persistent post-concussion symptoms |
| US12208167B1 (en) | 2024-02-06 | 2025-01-28 | Alpha Cognition Inc. | Coated tablets for pH-dependent release of benzgalantamine |
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| IT1248059B (it) * | 1991-06-14 | 1995-01-05 | Miat Spa | Insufflatore multidose per farmaci in polvere |
| CA2460118A1 (en) * | 2001-10-31 | 2003-05-08 | Pfizer Products Inc. | Nicotinic acetylcholine receptor agonists in the treatment of restless legs syndrome |
| US20040254146A1 (en) * | 2002-05-21 | 2004-12-16 | Nastech Pharmaceutical Company Inc. | Carboxylate salts of galantamine and their pharmaceutical use |
| DE10338544B4 (de) * | 2003-08-19 | 2017-08-31 | Janssen Pharmaceutica N.V. | Buccale Formulierungen des Galanthamins und deren Anwendungen |
| US20090253654A1 (en) * | 2005-09-22 | 2009-10-08 | Galantos Pharma Gmbh | Cholinergic enhancers with improved blood-brain barrier permeability for the treatment of diseases accompanied by cognitive impairment |
| JP2009508903A (ja) * | 2005-09-22 | 2009-03-05 | ガラントス ファルマ ゲゼルシャフト ミット ベシュレンクテル ハフツング | 認知障害を伴う疾患の治療に用いるための脳血液関門透過性が改善されたコリン作用増強剤 |
| US9808509B2 (en) * | 2007-06-08 | 2017-11-07 | Healthpartners Research Foundation | Pharmaceutical compositions and methods for enhancing targeting of therapeutic compounds to the central nervous system |
| JP2009197874A (ja) * | 2008-02-20 | 2009-09-03 | Works Bell:Kk | 動力伝達装置 |
| ES2463715T3 (es) * | 2008-04-14 | 2014-05-29 | Neurodyn Life Sciences Inc. | Derivados de galantamina como profármacos para el tratamiento de enfermedades del cerebro humano |
| US20130317117A1 (en) * | 2010-11-24 | 2013-11-28 | Pharmaceutics International, Inc. | Self micro-emulsifying drug delivery system with increased bioavailability |
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| EP2877165B1 (en) | 2018-09-05 |
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| AU2013294917B2 (en) | 2016-12-15 |
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| JP6272857B2 (ja) | 2018-01-31 |
| WO2014016430A1 (en) | 2014-01-30 |
| EP2877165A1 (en) | 2015-06-03 |
| JP2015524423A (ja) | 2015-08-24 |
| JP2018100272A (ja) | 2018-06-28 |
| CA2878135A1 (en) | 2014-01-30 |
| EP3417862B1 (en) | 2021-05-05 |
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