ES2699532T3 - Métodos y composiciones para mejorar la terapia antiangiogénica con anti-integrinas - Google Patents
Métodos y composiciones para mejorar la terapia antiangiogénica con anti-integrinas Download PDFInfo
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Applications Claiming Priority (2)
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| US201161466791P | 2011-03-23 | 2011-03-23 | |
| PCT/US2012/030204 WO2012129448A1 (en) | 2011-03-23 | 2012-03-22 | Methods and compositions for improving antiangiogenic therapy with anti-integrins |
Publications (1)
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| ES2699532T3 true ES2699532T3 (es) | 2019-02-11 |
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| CA (1) | CA2830908C (enExample) |
| ES (1) | ES2699532T3 (enExample) |
| WO (1) | WO2012129448A1 (enExample) |
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| CN103561761A (zh) * | 2011-03-23 | 2014-02-05 | 加利福尼亚大学董事会 | 用于使用抗-整合素改善抗血管生成疗法的方法和组合物 |
| WO2014105910A1 (en) * | 2012-12-26 | 2014-07-03 | Oncosynergy, Inc. | ANTI- INTEGRIN β1 ANTIBODY COMPOSITIONS AND METHODS OF USE THEREOF |
| EP3067698A1 (en) | 2015-03-11 | 2016-09-14 | Institut d'Investigació Biomèdica de Bellvitge (IDIBELL) | Pd-ecgf as biomarker of cancer |
| EP3067369A1 (en) | 2015-03-11 | 2016-09-14 | Institut d'Investigació Biomèdica de Bellvitge (IDIBELL) | Methods and compositions for the treatment of anti-angiogenic resistant cancer |
| WO2017032856A2 (en) | 2015-08-25 | 2017-03-02 | Histide Ag | Compounds for inducing tissue formation and uses thereof |
| KR20180050744A (ko) * | 2015-09-17 | 2018-05-23 | 히스티드 아게 | 신생물성 세포를 비-신생물성 세포로 전환시키기 위한 약제학적 회합물 및 이것의 용도 |
| WO2017046229A1 (en) * | 2015-09-17 | 2017-03-23 | Histide Ag | Pharmaceutical association of growth factor receptor agonist and adhesion protein inhibitor for converting a neoplastic cell into a non-neoplastic cell and uses thereof |
| HUE057153T2 (hu) * | 2015-09-17 | 2022-04-28 | Histide Ag | Neoplasztikus sejt nem neoplasztikus sejtté alakításához használt gyógyszerészeti együttes, mely egy növekedésifaktor-receptor agonistából és egy adhéziós fehérjeinhibitorból áll, és ezek felhasználása |
| WO2020145669A1 (ko) * | 2019-01-10 | 2020-07-16 | 에스지메디칼 주식회사 | 항 베타 1 인테그린 인간화 항체 및 이를 포함하는 암치료용 약학 조성물 |
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| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US5272263A (en) * | 1989-04-28 | 1993-12-21 | Biogen, Inc. | DNA sequences encoding vascular cell adhesion molecules (VCAMS) |
| US6033665A (en) | 1989-09-27 | 2000-03-07 | Elan Pharmaceuticals, Inc. | Compositions and methods for modulating leukocyte adhesion to brain endothelial cells |
| US6165467A (en) | 1991-07-20 | 2000-12-26 | Yoshihide Hagiwara | Stabilized human monoclonal antibody preparation |
| US5840300A (en) | 1995-09-11 | 1998-11-24 | Trustees Of The University Of Pennsylvania | Methods and compositions comprising single chain recombinant antibodies |
| US5846536A (en) * | 1996-10-04 | 1998-12-08 | The Regents Of The University Of California | Restoration of normal phenotype in cancer cells |
| US6596276B1 (en) | 1997-09-30 | 2003-07-22 | Beth Israel Deaconess Medical Center | Method for inhibiting tumor angiogenesis in a living subject |
| WO1999058139A2 (en) * | 1998-05-08 | 1999-11-18 | The Regents Of The University Of California | Methods for detecting and inhibiting angiogenesis |
| CA2359244C (en) | 1999-01-13 | 2013-10-08 | Bayer Corporation | .omega.-carboxy aryl substituted diphenyl ureas as p38 kinase inhibitors |
| EP1140840B1 (en) | 1999-01-13 | 2006-03-22 | Bayer Pharmaceuticals Corp. | -g(v)-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors |
| US7928239B2 (en) | 1999-01-13 | 2011-04-19 | Bayer Healthcare Llc | Inhibition of RAF kinase using quinolyl, isoquinolyl or pyridyl ureas |
| US6949245B1 (en) | 1999-06-25 | 2005-09-27 | Genentech, Inc. | Humanized anti-ErbB2 antibodies and treatment with anti-ErbB2 antibodies |
| US6716410B1 (en) | 1999-10-26 | 2004-04-06 | The Regents Of The University Of California | Reagents and methods for diagnosing, imaging and treating atherosclerotic disease |
| JP3789066B2 (ja) | 1999-12-08 | 2006-06-21 | 三菱電機株式会社 | 液晶表示装置 |
| US8725620B2 (en) | 2000-07-10 | 2014-05-13 | Nobuyoshi Morimoto | System and method for negotiating improved terms for products and services being purchased through the internet |
| US6995162B2 (en) | 2001-01-12 | 2006-02-07 | Amgen Inc. | Substituted alkylamine derivatives and methods of use |
| US6878714B2 (en) | 2001-01-12 | 2005-04-12 | Amgen Inc. | Substituted alkylamine derivatives and methods of use |
| WO2002097038A2 (en) * | 2001-05-25 | 2002-12-05 | Human Genome Sciences, Inc. | Chemokine beta-1 fusion proteins |
| JP4351043B2 (ja) | 2001-07-09 | 2009-10-28 | エラン ファーマシューティカルズ，インコーポレイテッド | アミロイド毒性の阻害方法 |
| US7307071B2 (en) | 2001-12-04 | 2007-12-11 | Onyx Pharmaceuticals, Inc | RAF-MEK-ERK pathway inhibitors to treat cancer |
| UA84156C2 (ru) | 2003-07-23 | 2008-09-25 | Байер Фармасьютикалс Корпорейшн | Фторозамещённая омега-карбоксиарилдифенилмочевина для лечения и профилактики болезней и состояний |
| TW200536851A (en) | 2004-01-23 | 2005-11-16 | Amgen Inc | Compounds and methods of use |
| WO2005117976A2 (en) * | 2004-06-03 | 2005-12-15 | The Regent Of The University Of California | Method of increasing radiation sensitivity by inhibition of beta one integrin |
| AU2006261920A1 (en) | 2005-06-23 | 2007-01-04 | Medimmune, Llc | Antibody formulations having optimized aggregation and fragmentation profiles |
| AR059066A1 (es) | 2006-01-27 | 2008-03-12 | Amgen Inc | Combinaciones del inhibidor de la angiopoyetina -2 (ang2) y el inhibidor del factor de crecimiento endotelial vascular (vegf) |
| JP4997432B2 (ja) | 2006-02-10 | 2012-08-08 | 学校法人慶應義塾 | 神経幹細胞の増殖抑制剤 |
| CN101448858B (zh) * | 2006-03-21 | 2013-06-12 | 健泰科生物技术公司 | 牵涉α5β1拮抗剂的联合疗法 |
| EP2366716A3 (en) * | 2006-03-21 | 2011-11-16 | Genentech, Inc. | Combinatorial therapy involving alpha5beta1 antagonists |
| WO2008031064A1 (en) * | 2006-09-07 | 2008-03-13 | University Of South Florida | Hyd1 peptides as anti-cancer agents |
| WO2009009114A2 (en) * | 2007-07-12 | 2009-01-15 | Oncomed Pharmaceuticals, Inc. | Compositions and methods for treating and diagnosing cancer |
| US20090041767A1 (en) * | 2007-07-27 | 2009-02-12 | Vanitha Ramakrishnan | Pharmaceutical combinations |
| EP2060287B1 (de) * | 2007-11-14 | 2011-06-15 | BrainLAB AG | Medikamentenzuführungssystem für CED (Convection Enhanced Delivery)-Katheterinfusionen |
| CA2734863A1 (en) * | 2008-08-20 | 2010-02-25 | New York Blood Center, Inc. | Regulation of integrin surface expression |
| EP2379596A1 (en) * | 2008-12-23 | 2011-10-26 | AstraZeneca AB | Targeted binding agents directed to 5 1 and uses therefor |
| SG10201609416XA (en) * | 2009-03-25 | 2016-12-29 | Genentech Inc | NOVEL ANTI-α5ß1 ANTIBODIES AND USES THEREOF |
| CN103561761A (zh) * | 2011-03-23 | 2014-02-05 | 加利福尼亚大学董事会 | 用于使用抗-整合素改善抗血管生成疗法的方法和组合物 |
| WO2014105910A1 (en) * | 2012-12-26 | 2014-07-03 | Oncosynergy, Inc. | ANTI- INTEGRIN β1 ANTIBODY COMPOSITIONS AND METHODS OF USE THEREOF |
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2012
- 2012-03-22 CN CN201280024596.8A patent/CN103561761A/zh active Pending
- 2012-03-22 AU AU2012230809A patent/AU2012230809B2/en active Active
- 2012-03-22 KR KR1020137027236A patent/KR20140030153A/ko not_active Ceased
- 2012-03-22 US US14/006,669 patent/US20140079637A1/en not_active Abandoned
- 2012-03-22 CA CA2830908A patent/CA2830908C/en active Active
- 2012-03-22 JP JP2014501258A patent/JP2014523398A/ja active Pending
- 2012-03-22 EP EP12760157.3A patent/EP2688585B1/en active Active
- 2012-03-22 WO PCT/US2012/030204 patent/WO2012129448A1/en not_active Ceased
- 2012-03-22 ES ES12760157T patent/ES2699532T3/es active Active
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2018
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2021
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Also Published As
| Publication number | Publication date |
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| EP2688585A1 (en) | 2014-01-29 |
| AU2012230809A1 (en) | 2013-10-10 |
| CA2830908C (en) | 2019-09-24 |
| CA2830908A1 (en) | 2012-09-27 |
| CN103561761A (zh) | 2014-02-05 |
| US20180236073A1 (en) | 2018-08-23 |
| WO2012129448A1 (en) | 2012-09-27 |
| US20140079637A1 (en) | 2014-03-20 |
| AU2012230809B2 (en) | 2017-06-29 |
| US11185585B2 (en) | 2021-11-30 |
| EP2688585A4 (en) | 2015-05-06 |
| KR20140030153A (ko) | 2014-03-11 |
| US20220111045A1 (en) | 2022-04-14 |
| JP2014523398A (ja) | 2014-09-11 |
| EP2688585B1 (en) | 2018-09-05 |
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