ES2696074T3 - Tratamiento del cáncer de mama - Google Patents
Tratamiento del cáncer de mama Download PDFInfo
- Publication number
- ES2696074T3 ES2696074T3 ES12846720T ES12846720T ES2696074T3 ES 2696074 T3 ES2696074 T3 ES 2696074T3 ES 12846720 T ES12846720 T ES 12846720T ES 12846720 T ES12846720 T ES 12846720T ES 2696074 T3 ES2696074 T3 ES 2696074T3
- Authority
- ES
- Spain
- Prior art keywords
- trip trip
- tio
- tra
- breast cancer
- amen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 0 C*(C)(C)C(c1ccc(*(C(C)(C)C(*2c(cc3)cc(*)c3[Zn])=O)C2=*)cc1N)O Chemical compound C*(C)(C)C(c1ccc(*(C(C)(C)C(*2c(cc3)cc(*)c3[Zn])=O)C2=*)cc1N)O 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161513361P | 2011-07-29 | 2011-07-29 | |
| PCT/US2012/048471 WO2013066440A1 (en) | 2011-07-29 | 2012-07-27 | Treatment of breast cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2696074T3 true ES2696074T3 (es) | 2019-01-14 |
Family
ID=48192564
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES12846720T Active ES2696074T3 (es) | 2011-07-29 | 2012-07-27 | Tratamiento del cáncer de mama |
Country Status (18)
| Country | Link |
|---|---|
| US (4) | US9517229B2 (cg-RX-API-DMAC7.html) |
| EP (4) | EP2739153B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP6158180B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR101923250B1 (cg-RX-API-DMAC7.html) |
| CN (1) | CN103997894B (cg-RX-API-DMAC7.html) |
| BR (1) | BR112014002200A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2843417C (cg-RX-API-DMAC7.html) |
| CY (1) | CY1121038T1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK2739153T3 (cg-RX-API-DMAC7.html) |
| EA (1) | EA028452B1 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2696074T3 (cg-RX-API-DMAC7.html) |
| HU (1) | HUE040524T2 (cg-RX-API-DMAC7.html) |
| MX (1) | MX359664B (cg-RX-API-DMAC7.html) |
| PH (1) | PH12014500248B1 (cg-RX-API-DMAC7.html) |
| PL (1) | PL2739153T3 (cg-RX-API-DMAC7.html) |
| PT (1) | PT2739153T (cg-RX-API-DMAC7.html) |
| SI (1) | SI2739153T1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2013066440A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2739153B1 (en) * | 2011-07-29 | 2018-08-22 | Medivation Prostate Therapeutics LLC | Treatment of breast cancer |
| GB201216017D0 (en) | 2012-09-07 | 2012-10-24 | Cancer Rec Tech Ltd | Inhibitor compounds |
| LT3305285T (lt) | 2012-09-26 | 2020-12-10 | Aragon Pharmaceuticals, Inc. | Anti-androgenai, skirti gydyti nametastazavusį kastracijai atsparų prostatos vėžį |
| JOP20200097A1 (ar) | 2013-01-15 | 2017-06-16 | Aragon Pharmaceuticals Inc | معدل مستقبل أندروجين واستخداماته |
| US9937169B2 (en) * | 2013-04-17 | 2018-04-10 | Signal Pharmaceuticals, Llc | Methods for treating cancer using dihydropyrazino-pyrazine compound combination therapy |
| AU2013404949B2 (en) * | 2013-11-07 | 2018-10-18 | Deciphera Pharmaceuticals, Llc | Methods for inhibiting TIE2 kinase useful in the treatment of cancer |
| JP6945587B2 (ja) * | 2013-11-07 | 2021-10-06 | デシフェラ ファーマシューティカルズ,エルエルシー | ガンの処置に有用なtie2キナーゼの阻害方法 |
| EP3148336B1 (en) | 2014-05-28 | 2019-10-02 | Eisai R&D Management Co., Ltd. | Eribulin and poly (adp ribose) polymerase (parp) inhibitors as combination therapy for the treatment of cancer |
| MX2017007707A (es) | 2014-12-12 | 2018-03-06 | Medivation Prostate Therapeutics Llc | Metodo para predecir respuesta a agentes terapeuticos de cancer de mama y metodo de tratamiento de cancer de mama. |
| WO2016141167A1 (en) | 2015-03-03 | 2016-09-09 | Cureport, Inc. | Combination liposomal pharmaceutical formulations |
| US10736845B2 (en) | 2015-03-03 | 2020-08-11 | Cureport Inc. | Dual loaded liposomal pharmaceutical formulations |
| CN104857517B (zh) * | 2015-05-14 | 2018-04-27 | 南京海纳医药科技股份有限公司 | 一种恩杂鲁胺软胶囊及其制备方法 |
| US9963433B2 (en) * | 2016-01-29 | 2018-05-08 | Wayne State University | Anticancer drugs including the chemical structures of an androgen receptor ligand and a histone deacetylase inhibitor |
| KR102795129B1 (ko) | 2017-06-22 | 2025-04-15 | 셀진 코포레이션 | B형 간염 바이러스 감염을 특징으로 하는 간세포 암종의 치료 |
| CA3079135A1 (en) | 2017-10-16 | 2019-04-25 | Arturo Molina | Anti-androgens for the treatment of non-metastatic castration-resistant prostate cancer |
| CN107987055A (zh) * | 2017-12-19 | 2018-05-04 | 刘秀云 | 硫代咪唑二酮类雄激素受体拮抗剂及其用途 |
| BR112020015581A2 (pt) | 2018-01-31 | 2021-02-02 | Deciphera Pharmaceuticals, Llc | terapia de combinação para o tratamento de tumores estromais gastrointestinais |
| SG11202007287XA (en) | 2018-01-31 | 2020-08-28 | Deciphera Pharmaceuticals Llc | Combination therapy for the treatment of mastocytosis |
| WO2020113088A1 (en) * | 2018-11-30 | 2020-06-04 | Nuvation Bio Inc. | Diarylhydantoin compounds and methods of use thereof |
| AU2019387370A1 (en) | 2018-11-30 | 2021-06-10 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
| WO2021030405A1 (en) | 2019-08-12 | 2021-02-18 | Deciphera Pharmaceuticals, Llc | Ripretinib for treating gastrointestinal stromal tumors |
| KR20220045189A (ko) | 2019-08-12 | 2022-04-12 | 데시페라 파마슈티칼스, 엘엘씨. | 위장관 기질 종양을 치료하는 방법 |
| CN119950433A (zh) | 2019-12-30 | 2025-05-09 | 德西费拉制药有限责任公司 | 非晶型激酶抑制剂制剂及其使用方法 |
| PL4084779T3 (pl) | 2019-12-30 | 2025-02-24 | Deciphera Pharmaceuticals, Llc | Kompozycje 1-(4-bromo-5-(1-etylo-7-(metyloamino)-2-okso-1,2-dihydro-1,6-naftyrydyn-3-ylo)-2-fluorofenylo)-3-fenylomocznika |
| EP4188330A4 (en) * | 2020-08-03 | 2024-09-04 | Oncocyte Corporation | CLASSIFICATION OF TUMORS AND PREDICTION OF RESPONSE |
| US11779572B1 (en) | 2022-09-02 | 2023-10-10 | Deciphera Pharmaceuticals, Llc | Methods of treating gastrointestinal stromal tumors |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4559157A (en) | 1983-04-21 | 1985-12-17 | Creative Products Resource Associates, Ltd. | Cosmetic applicator useful for skin moisturizing |
| LU84979A1 (fr) | 1983-08-30 | 1985-04-24 | Oreal | Composition cosmetique ou pharmaceutique sous forme aqueuse ou anhydre dont la phase grasse contient un polyether oligomere et polyethers oligomeres nouveaux |
| US4820508A (en) | 1987-06-23 | 1989-04-11 | Neutrogena Corporation | Skin protective composition |
| US4992478A (en) | 1988-04-04 | 1991-02-12 | Warner-Lambert Company | Antiinflammatory skin moisturizing composition and method of preparing same |
| US4938949A (en) | 1988-09-12 | 1990-07-03 | University Of New York | Treatment of damaged bone marrow and dosage units therefor |
| US7709517B2 (en) | 2005-05-13 | 2010-05-04 | The Regents Of The University Of California | Diarylhydantoin compounds |
| KR101332924B1 (ko) * | 2005-05-13 | 2013-11-26 | 더 리전트 오브 더 유니버시티 오브 캘리포니아 | 디아릴히단토인 화합물 |
| EP1954708A4 (en) | 2005-11-23 | 2009-05-13 | Univ Utah Res Found | Methods and compositions involving intrinsic genes |
| SI3412290T1 (sl) | 2006-03-27 | 2021-09-30 | The Regents Of The University Of California | Modulator androgenih receptorjev za zdravljenje raka prostate in bolezni, povezanih z androgenimi receptorji |
| CN102755318B (zh) | 2006-03-29 | 2014-09-10 | 加利福尼亚大学董事会 | 二芳基硫代乙内酰脲化合物 |
| PE20121470A1 (es) * | 2007-10-26 | 2012-11-18 | Univ California | Compuestos de diarilhidantoina como antagonistas del receptor de androgeno |
| US8450290B2 (en) * | 2007-11-26 | 2013-05-28 | Enzon Pharmaceuticals, Inc. | Methods for treating androgen receptor dependent disorders including cancers |
| WO2009114534A1 (en) * | 2008-03-14 | 2009-09-17 | The Regents Of The University Of California | Multi-gene classifiers and prognostic indicators for cancers |
| PL2297359T4 (pl) | 2008-05-30 | 2014-07-31 | Univ North Carolina Chapel Hill | Profile ekspresji genów do przewidywania skutków raka piersi |
| JP2012518661A (ja) | 2009-02-24 | 2012-08-16 | メディベイション プロステイト セラピューティクス, インコーポレイテッド | 特定のジアリールヒダントインおよびジアリールチオヒダントイン化合物 |
| EP2416657A4 (en) | 2009-04-09 | 2012-09-05 | Medivation Prostate Therapeutics Inc | COMPOUNDS COMPRISING SUBSTITUTED DI-ARYLHYDANTOIDS AND DI-ARYLTHIOHYDANTOINES AND METHODS OF USE THEREOF |
| US8507195B2 (en) * | 2009-08-20 | 2013-08-13 | The Regents Of The University Of Colorado | MiRNAs dysregulated in triple-negative breast cancer |
| EP2485804A4 (en) | 2009-10-07 | 2015-07-29 | Medivation Technologies Inc | SUBSTITUTED PHENYLCARBAMOYL ALKYLAMINOAREN COMPOUNDS AND N, N'-BIS-ARYL UREA COMPOUNDS |
| EP2685988A4 (en) | 2011-03-15 | 2014-08-20 | Univ North Carolina | Methods of treating breast cancer with anthracycline therapy |
| EP2739153B1 (en) * | 2011-07-29 | 2018-08-22 | Medivation Prostate Therapeutics LLC | Treatment of breast cancer |
| WO2013082440A2 (en) | 2011-11-30 | 2013-06-06 | The University Of North Carolina At Chapel Hill | Methods of treating breast cancer with taxane therapy |
| AU2013306380A1 (en) | 2012-08-23 | 2015-03-05 | The Regents Of The University Of Colorado, A Body Corporate | Method for determining breast cancer treatment |
| US9175291B2 (en) | 2012-10-11 | 2015-11-03 | Isis Pharmaceuticals Inc. | Modulation of androgen receptor expression |
| US20140154681A1 (en) | 2012-11-12 | 2014-06-05 | Nanostring Technologies, Inc. | Methods to Predict Breast Cancer Outcome |
| US10679730B2 (en) | 2013-05-28 | 2020-06-09 | The University Of Chicago | Prognostic and predictive breast cancer signature |
| MX2017007707A (es) | 2014-12-12 | 2018-03-06 | Medivation Prostate Therapeutics Llc | Metodo para predecir respuesta a agentes terapeuticos de cancer de mama y metodo de tratamiento de cancer de mama. |
-
2012
- 2012-07-27 EP EP12846720.6A patent/EP2739153B1/en active Active
- 2012-07-27 SI SI201231453T patent/SI2739153T1/sl unknown
- 2012-07-27 WO PCT/US2012/048471 patent/WO2013066440A1/en not_active Ceased
- 2012-07-27 EP EP19187649.9A patent/EP3610731A1/en not_active Withdrawn
- 2012-07-27 ES ES12846720T patent/ES2696074T3/es active Active
- 2012-07-27 US US14/236,036 patent/US9517229B2/en active Active
- 2012-07-27 KR KR1020147005617A patent/KR101923250B1/ko active Active
- 2012-07-27 CA CA2843417A patent/CA2843417C/en active Active
- 2012-07-27 DK DK12846720.6T patent/DK2739153T3/en active
- 2012-07-27 EP EP20191500.6A patent/EP3791724A1/en not_active Withdrawn
- 2012-07-27 CN CN201280048192.2A patent/CN103997894B/zh active Active
- 2012-07-27 EA EA201400178A patent/EA028452B1/ru not_active IP Right Cessation
- 2012-07-27 PL PL12846720T patent/PL2739153T3/pl unknown
- 2012-07-27 EP EP18190012.7A patent/EP3430907A1/en not_active Withdrawn
- 2012-07-27 BR BR112014002200A patent/BR112014002200A2/pt not_active Application Discontinuation
- 2012-07-27 PH PH1/2014/500248A patent/PH12014500248B1/en unknown
- 2012-07-27 MX MX2014001218A patent/MX359664B/es active IP Right Grant
- 2012-07-27 HU HUE12846720A patent/HUE040524T2/hu unknown
- 2012-07-27 PT PT12846720T patent/PT2739153T/pt unknown
- 2012-07-27 JP JP2014523048A patent/JP6158180B2/ja active Active
-
2016
- 2016-12-09 US US15/373,914 patent/US10111861B2/en active Active
-
2017
- 2017-03-31 JP JP2017072819A patent/JP2017141269A/ja active Pending
-
2018
- 2018-10-24 US US16/168,896 patent/US20190262315A1/en not_active Abandoned
- 2018-11-08 CY CY181101174T patent/CY1121038T1/el unknown
-
2020
- 2020-01-22 US US16/749,133 patent/US20210069154A1/en not_active Abandoned
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