ES2682255T3 - Métodos mejorados de tratamiento de isquemia - Google Patents

Métodos mejorados de tratamiento de isquemia Download PDF

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Publication number
ES2682255T3
ES2682255T3 ES12852924.5T ES12852924T ES2682255T3 ES 2682255 T3 ES2682255 T3 ES 2682255T3 ES 12852924 T ES12852924 T ES 12852924T ES 2682255 T3 ES2682255 T3 ES 2682255T3
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Spain
Prior art keywords
stem
progenitor cells
cells
tissue
ischemia
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ES12852924.5T
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English (en)
Spanish (es)
Inventor
Dan Shoemaker
Pratik S. Multani
John D. Mendlein
David Robbins
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Fate Therapeutics Inc
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Fate Therapeutics Inc
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    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
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    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0647Haematopoietic stem cells; Uncommitted or multipotent progenitors
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    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/02Compounds of the arachidonic acid pathway, e.g. prostaglandins, leukotrienes
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
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  • Zoology (AREA)
  • Biotechnology (AREA)
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ES12852924.5T 2011-12-02 2012-11-29 Métodos mejorados de tratamiento de isquemia Active ES2682255T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161566494P 2011-12-02 2011-12-02
US201161566494P 2011-12-02
PCT/US2012/066984 WO2013082241A2 (en) 2011-12-02 2012-11-29 Improved methods of treating ischemia

Publications (1)

Publication Number Publication Date
ES2682255T3 true ES2682255T3 (es) 2018-09-19

Family

ID=48536234

Family Applications (1)

Application Number Title Priority Date Filing Date
ES12852924.5T Active ES2682255T3 (es) 2011-12-02 2012-11-29 Métodos mejorados de tratamiento de isquemia

Country Status (5)

Country Link
US (3) US10111907B2 (enExample)
EP (2) EP2785350B1 (enExample)
JP (5) JP6106688B2 (enExample)
ES (1) ES2682255T3 (enExample)
WO (1) WO2013082241A2 (enExample)

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PT2785834T (pt) 2011-12-02 2020-11-13 Fate Therapeutics Inc Composição de células estaminais melhorada
US10111907B2 (en) * 2011-12-02 2018-10-30 Fate Therapeutics, Inc. Methods of treating ischemia
WO2014093531A1 (en) * 2012-12-11 2014-06-19 Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center Modulation of myofiber repair by anti-myostatin in strategies with stem cells
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KR101674253B1 (ko) * 2014-07-16 2016-11-08 연세대학교 산학협력단 트랜스웰 및 케모카인을 이용한 줄기세포의 분리 방법
HK1247958A1 (zh) * 2015-05-05 2018-10-05 菲特治疗公司 T淋巴细胞的调节
KR20180033537A (ko) 2015-07-21 2018-04-03 더 칠드런스 메디칼 센터 코포레이션 Pd-l1 발현 조혈 줄기 세포 및 용도
WO2017026838A1 (ko) * 2015-08-12 2017-02-16 주식회사 차바이오텍 향상된 탯줄 유래 부착형 줄기세포, 그의 제조방법 및 용도
ES2914692T3 (es) 2015-08-12 2022-06-15 Cha Biotech Co Ltd Células madre adhesivas derivadas de cordón umbilical mejoradas, método de preparación para las mismas, y uso de las mismas
JP2018528970A (ja) * 2015-09-16 2018-10-04 サントル、ナショナール、ド、ラ、ルシェルシュ、シアンティフィク、(セーエヌエルエス) 悪性腫瘍を治療および/または腫瘍再発を予防するためのゲル化組成物
US9918994B2 (en) 2016-03-04 2018-03-20 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for muscle regeneration using prostaglandin E2
AU2017225999B2 (en) * 2016-03-04 2022-08-18 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for muscle regeneration using prostaglandin E2
KR102002671B1 (ko) * 2016-11-11 2019-07-23 사회복지법인 삼성생명공익재단 2dg를 이용한 줄기세포 역량 향상 방법
CA3065945A1 (en) 2017-06-09 2018-12-13 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for preventing or treating muscle conditions
US11879137B2 (en) 2017-09-22 2024-01-23 The Children's Medical Center Corporation Treatment of type 1 diabetes and autoimmune diseases or disorders
WO2019102761A1 (ja) 2017-11-24 2019-05-31 Kyb株式会社 筒型リニアモータ
GB202211232D0 (en) 2022-08-02 2022-09-14 Heptares Therapeutics Ltd Prostaglandin EP4 receptor agonist compounds
CN116966302B (zh) * 2023-06-28 2025-11-25 华中科技大学同济医学院附属协和医院 Areg的新用途

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