ES268058A1 - Procedimiento de obtenciën de nuevos derivados de tiocolchicina - Google Patents
Procedimiento de obtenciën de nuevos derivados de tiocolchicinaInfo
- Publication number
- ES268058A1 ES268058A1 ES0268058A ES268058A ES268058A1 ES 268058 A1 ES268058 A1 ES 268058A1 ES 0268058 A ES0268058 A ES 0268058A ES 268058 A ES268058 A ES 268058A ES 268058 A1 ES268058 A1 ES 268058A1
- Authority
- ES
- Spain
- Prior art keywords
- group containing
- carbon atoms
- alkali metal
- thiocolchicine
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- CMEGANPVAXDBPL-INIZCTEOSA-N n-[(7s)-1,2,3-trimethoxy-10-methylsulfanyl-9-oxo-6,7-dihydro-5h-benzo[a]heptalen-7-yl]acetamide Chemical class C1([C@@H](NC(C)=O)CC2)=CC(=O)C(SC)=CC=C1C1=C2C=C(OC)C(OC)=C1OC CMEGANPVAXDBPL-INIZCTEOSA-N 0.000 title abstract 2
- -1 alkali metal salts Chemical class 0.000 abstract 4
- 125000004432 carbon atom Chemical group C* 0.000 abstract 4
- 229910052783 alkali metal Inorganic materials 0.000 abstract 3
- 208000020584 Polyploidy Diseases 0.000 abstract 2
- 125000004450 alkenylene group Chemical group 0.000 abstract 2
- 125000002947 alkylene group Chemical group 0.000 abstract 2
- 239000007864 aqueous solution Substances 0.000 abstract 2
- 125000000732 arylene group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 2
- NUNCOHUMTCDISK-AWEZNQCLSA-N (7s)-7-amino-1,2,3-trimethoxy-10-methylsulfanyl-6,7-dihydro-5h-benzo[a]heptalen-9-one Chemical class C1([C@@H](N)CC2)=CC(=O)C(SC)=CC=C1C1=C2C=C(OC)C(OC)=C1OC NUNCOHUMTCDISK-AWEZNQCLSA-N 0.000 abstract 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 abstract 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 abstract 1
- OFOBLEOULBTSOW-UHFFFAOYSA-N Malonic acid Chemical compound OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000008065 acid anhydrides Chemical class 0.000 abstract 1
- 150000008044 alkali metal hydroxides Chemical class 0.000 abstract 1
- 230000002927 anti-mitotic effect Effects 0.000 abstract 1
- 239000003080 antimitotic agent Substances 0.000 abstract 1
- 239000007900 aqueous suspension Substances 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- ORTFAQDWJHRMNX-UHFFFAOYSA-N hydroxidooxidocarbon(.) Chemical compound O[C]=O ORTFAQDWJHRMNX-UHFFFAOYSA-N 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 159000000000 sodium salts Chemical class 0.000 abstract 1
- 239000002689 soil Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 238000005507 spraying Methods 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH664760A CH391694A (de) | 1960-06-10 | 1960-06-10 | Verfahren zur Herstellung von neuen Thiocolchicin-Derivaten |
| CH367861 | 1961-03-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES268058A1 true ES268058A1 (es) | 1961-12-16 |
Family
ID=25693598
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0268058A Expired ES268058A1 (es) | 1960-06-10 | 1961-06-08 | Procedimiento de obtenciën de nuevos derivados de tiocolchicina |
Country Status (3)
| Country | Link |
|---|---|
| ES (1) | ES268058A1 (en:Method) |
| GB (1) | GB977470A (en:Method) |
| LU (1) | LU40236A1 (en:Method) |
-
1961
- 1961-05-08 GB GB1663461A patent/GB977470A/en not_active Expired
- 1961-06-08 LU LU40236A patent/LU40236A1/xx unknown
- 1961-06-08 ES ES0268058A patent/ES268058A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| LU40236A1 (en:Method) | 1961-12-08 |
| GB977470A (en) | 1964-12-09 |
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