ES2670700T3 - Tratamiento de gota e hiperuricemia - Google Patents
Tratamiento de gota e hiperuricemia Download PDFInfo
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- ES2670700T3 ES2670700T3 ES11796324.9T ES11796324T ES2670700T3 ES 2670700 T3 ES2670700 T3 ES 2670700T3 ES 11796324 T ES11796324 T ES 11796324T ES 2670700 T3 ES2670700 T3 ES 2670700T3
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- gout
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- allopurinol
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- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
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- A—HUMAN NECESSITIES
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
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- A61P19/00—Drugs for skeletal disorders
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
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- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| US41144910P | 2010-11-08 | 2010-11-08 | |
| US201161430522P | 2011-01-06 | 2011-01-06 | |
| US201161430522P | 2011-01-06 | ||
| US201161489420P | 2011-05-24 | 2011-05-24 | |
| US201161489420P | 2011-05-24 | ||
| PCT/US2011/040398 WO2011159732A1 (en) | 2010-06-15 | 2011-06-14 | Treatment of gout and hyperuricemia |
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| WO (1) | WO2011159732A1 (OSRAM) |
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| CA2794798C (en) | 2010-03-30 | 2017-05-30 | Ardea Biosciences, Inc. | Treatment of gout |
| LT2582683T (lt) * | 2010-06-15 | 2018-06-11 | Ardea Biosciences, Inc. | Podagros ir hiperuricemijos gydymas |
| PL2776028T3 (pl) * | 2011-11-03 | 2019-03-29 | Ardea Biosciences, Inc. | 3,4-di-podstawiony związek pirydynowy, sposoby jego zastosowania i zawierające go kompozycje |
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| US8883857B2 (en) | 2012-12-07 | 2014-11-11 | Baylor College Of Medicine | Small molecule xanthine oxidase inhibitors and methods of use |
| CN103613552A (zh) * | 2013-12-02 | 2014-03-05 | 苏州晶云药物科技有限公司 | 2-(5-溴-4-(4-环丙基萘-1-基)-4h-1，2，4-三唑-3-基硫基)乙酸钠的新晶型及其制备方法 |
| US9969701B2 (en) | 2013-12-20 | 2018-05-15 | Crystal Pharmatech Co., Ltd. | Salts and co-crystals of lesinurad |
| CN103755651A (zh) * | 2013-12-23 | 2014-04-30 | 苏州晶云药物科技有限公司 | 2-(5-溴-4-(4-环丙基萘-1-基)-4h-1，2，4-三唑-3-基硫基)乙酸的盐的新晶型及其制备方法 |
| JP2015160847A (ja) * | 2014-02-28 | 2015-09-07 | ベイラー カレッジ オブ メディスンＢａｙｌｏｒ Ｃｏｌｌｅｇｅ Ｏｆ Ｍｅｄｉｃｉｎｅ | 小分子のキサンチンオキシダーゼ阻害剤および使用方法 |
| CN105622531A (zh) | 2015-04-03 | 2016-06-01 | 南京明德新药研发股份有限公司 | 轴手性异构体及其制备方法和制药用途 |
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| CN108289848A (zh) * | 2015-12-08 | 2018-07-17 | 阿迪亚生命科学公司 | 包含urat1的有效抑制剂的药物组合物 |
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| US20060189811A1 (en) | 2004-07-23 | 2006-08-24 | Fujiyakuhin Co., Ltd. | Process for producing 1,2,4-triazole compound and intermediate therefor |
| EP2433633A1 (en) | 2004-08-25 | 2012-03-28 | Ardea Biosciences, Inc. | Triazolyl alpha -mercaptoacetanildes as inhibitors of HIV reverse transcriptase |
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| AU2008206231A1 (en) | 2007-01-19 | 2008-07-24 | Takeda Pharmaceuticals U.S.A., Inc. | Methods for preventing or reducing the number of gout flares using xanthine oxidoreductase inhibitors and anti-inflammatory agents |
| MX2010005776A (es) | 2007-11-27 | 2010-08-31 | Ardea Biosciences Inc | Nuevos compuestos y composiciones y metodos de uso. |
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| CN103819419B (zh) | 2008-09-04 | 2016-12-07 | 亚德生化公司 | 调节尿酸含量的化合物、组合物及其使用方法 |
| US8242154B2 (en) | 2008-09-04 | 2012-08-14 | Ardea Biosciences, Inc. | Compounds, compositions and methods of using same for modulating uric acid levels |
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| BR112012016795A2 (pt) | 2010-01-08 | 2020-09-01 | Ardea Biosciences Inc. | formas polimórficas, cristalinas e de mesofase de 2-(5- bromo -4-(4-ciclopropilnaftalen-1-il)-4h-1,2,34-triazol-3iltio) acetato de sódio e seus usos |
| CA2794798C (en) * | 2010-03-30 | 2017-05-30 | Ardea Biosciences, Inc. | Treatment of gout |
| LT2582683T (lt) * | 2010-06-15 | 2018-06-11 | Ardea Biosciences, Inc. | Podagros ir hiperuricemijos gydymas |
| EP2588110B1 (en) * | 2010-07-02 | 2018-10-17 | University Health Network | Methods of targeting pten mutant diseases and compositions therefor |
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| LT2714669T (lt) | 2011-05-24 | 2017-08-10 | Ardea Biosciences, Inc. | Hipertenzija ir hiperurikemija |
-
2011
- 2011-06-14 LT LTEP11796324.9T patent/LT2582683T/lt unknown
- 2011-06-14 DK DK11796324.9T patent/DK2582683T3/en active
- 2011-06-14 CA CA2802407A patent/CA2802407C/en not_active Expired - Fee Related
- 2011-06-14 JP JP2013515459A patent/JP5964821B2/ja not_active Expired - Fee Related
- 2011-06-14 ES ES11796324.9T patent/ES2670700T3/es active Active
- 2011-06-14 PL PL11796324T patent/PL2582683T3/pl unknown
- 2011-06-14 TR TR2018/06828T patent/TR201806828T4/tr unknown
- 2011-06-14 PT PT117963249T patent/PT2582683T/pt unknown
- 2011-06-14 SI SI201131474T patent/SI2582683T1/en unknown
- 2011-06-14 EP EP11796324.9A patent/EP2582683B1/en not_active Revoked
- 2011-06-14 HR HRP20180780TT patent/HRP20180780T1/hr unknown
- 2011-06-14 US US13/704,192 patent/US9216179B2/en active Active
- 2011-06-14 HU HUE11796324A patent/HUE038265T2/hu unknown
- 2011-06-14 RS RS20180571A patent/RS57275B1/sr unknown
- 2011-06-14 SM SM20180266T patent/SMT201800266T1/it unknown
- 2011-06-14 WO PCT/US2011/040398 patent/WO2011159732A1/en not_active Ceased
-
2013
- 2013-01-03 ZA ZA2013/00055A patent/ZA201300055B/en unknown
-
2015
- 2015-11-12 US US14/939,963 patent/US20160143889A1/en not_active Abandoned
-
2018
- 2018-05-18 CY CY20181100520T patent/CY1120473T1/el unknown
- 2018-09-19 US US16/135,153 patent/US20190015392A1/en not_active Abandoned
-
2019
- 2019-02-19 NO NO2019008C patent/NO2019008I1/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SI2582683T1 (en) | 2018-07-31 |
| CA2802407A1 (en) | 2011-12-22 |
| PL2582683T3 (pl) | 2018-08-31 |
| DK2582683T3 (en) | 2018-06-06 |
| US20190015392A1 (en) | 2019-01-17 |
| EP2582683A1 (en) | 2013-04-24 |
| US9216179B2 (en) | 2015-12-22 |
| HUE038265T2 (hu) | 2018-10-29 |
| JP5964821B2 (ja) | 2016-08-03 |
| SMT201800266T1 (it) | 2018-07-17 |
| NO2019008I1 (no) | 2019-02-19 |
| TR201806828T4 (tr) | 2018-06-21 |
| HRP20180780T1 (hr) | 2018-07-13 |
| CY1120473T1 (el) | 2019-07-10 |
| WO2011159732A1 (en) | 2011-12-22 |
| PT2582683T (pt) | 2018-05-25 |
| EP2582683A4 (en) | 2014-04-30 |
| JP2013528650A (ja) | 2013-07-11 |
| LT2582683T (lt) | 2018-06-11 |
| US20130178484A1 (en) | 2013-07-11 |
| US20160143889A1 (en) | 2016-05-26 |
| CA2802407C (en) | 2018-01-23 |
| RS57275B1 (sr) | 2018-08-31 |
| ZA201300055B (en) | 2018-05-30 |
| EP2582683B1 (en) | 2018-03-21 |
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