ES2669620T3 - Biomarcadores relacionados con el avance de la resistencia a la insulina y métodos que lo utilizan - Google Patents
Biomarcadores relacionados con el avance de la resistencia a la insulina y métodos que lo utilizan Download PDFInfo
- Publication number
- ES2669620T3 ES2669620T3 ES14746017.4T ES14746017T ES2669620T3 ES 2669620 T3 ES2669620 T3 ES 2669620T3 ES 14746017 T ES14746017 T ES 14746017T ES 2669620 T3 ES2669620 T3 ES 2669620T3
- Authority
- ES
- Spain
- Prior art keywords
- biomarkers
- subject
- levels
- diabetes
- insulin resistance
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16Z—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS, NOT OTHERWISE PROVIDED FOR
- G16Z99/00—Subject matter not provided for in other main groups of this subclass
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/04—Endocrine or metabolic disorders
- G01N2800/042—Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
- G01N2800/324—Coronary artery diseases, e.g. angina pectoris, myocardial infarction
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/50—Determining the risk of developing a disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Chemical & Material Sciences (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Medical Informatics (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Databases & Information Systems (AREA)
- Epidemiology (AREA)
- Primary Health Care (AREA)
- Data Mining & Analysis (AREA)
- Tropical Medicine & Parasitology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361758924P | 2013-01-31 | 2013-01-31 | |
| US201361758924P | 2013-01-31 | ||
| PCT/US2014/011759 WO2014120449A1 (en) | 2013-01-31 | 2014-01-16 | Biomarkers related to insulin resistance progression and methods using the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2669620T3 true ES2669620T3 (es) | 2018-05-28 |
Family
ID=51262841
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES14746017.4T Active ES2669620T3 (es) | 2013-01-31 | 2014-01-16 | Biomarcadores relacionados con el avance de la resistencia a la insulina y métodos que lo utilizan |
| ES17209399T Active ES2987582T3 (es) | 2013-01-31 | 2014-01-16 | Biomarcadores relacionados con la progresión de la resistencia a la Insulina y métodos que lo utilizan |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES17209399T Active ES2987582T3 (es) | 2013-01-31 | 2014-01-16 | Biomarcadores relacionados con la progresión de la resistencia a la Insulina y métodos que lo utilizan |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US9910047B2 (enExample) |
| EP (2) | EP3321686B1 (enExample) |
| JP (1) | JP6404834B2 (enExample) |
| ES (2) | ES2669620T3 (enExample) |
| WO (1) | WO2014120449A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105074460B (zh) * | 2013-03-28 | 2018-06-15 | 雀巢产品技术援助有限公司 | 作为用于重量增加预防的益生元功效的生物标记物的硫酸吲哚酚 |
| MX2016000293A (es) * | 2013-07-09 | 2016-06-21 | Stemina Biomarker Discovery Inc | Biomarcadores del trastrono del espectro autista. |
| CN109154619A (zh) * | 2016-05-17 | 2019-01-04 | 国立大学法人大阪大学 | 用于判定糖尿病的血液试样的分析方法及系统 |
| DK3465202T3 (da) * | 2016-06-02 | 2023-08-21 | Metabolon Inc | Massespektrometrifremgangsmåde til detektering og kvantitering af metabolitter |
| ES3004083T3 (en) * | 2016-12-19 | 2025-03-11 | Metabolon Inc | Mass spectrometry assay method for detection and quantitation of kidney function metabolites |
| WO2018150077A1 (en) * | 2017-02-16 | 2018-08-23 | Afekta Technologies Oy | Betaine biomarkers for nutritional status, nutritional regimen, endogenous metabolism, or risk of cardiovascular or metabolic diseases |
| EP4220157B1 (en) | 2017-03-31 | 2025-05-14 | Quest Diagnostics Investments LLC | Methods for quantitation of insulin and c-peptide |
| EP3401683A1 (en) * | 2017-05-10 | 2018-11-14 | Eberhard Karls Universität Tübingen Medizinische Fakultät | Diagnosing metabolic disease by the use of a biomarker |
| CN111727038B (zh) * | 2018-01-17 | 2025-05-13 | 南安普顿大学 | 肌肉减少症和nad缺乏的风险预测及分级方法 |
| JP2022501579A (ja) * | 2018-09-27 | 2022-01-06 | ソシエテ・デ・プロデュイ・ネスレ・エス・アー | 小児期及び若年成人期においてインスリン抵抗性を発症するリスクについてのマーカー |
| US11041847B1 (en) * | 2019-01-25 | 2021-06-22 | Ixcela, Inc. | Detection and modification of gut microbial population |
| KR102231928B1 (ko) * | 2019-09-19 | 2021-03-26 | 고려대학교 산학협력단 | 비만대사수술 이후 당뇨병 예후 예측용 바이오마커 조성물 |
| CA3177108A1 (en) * | 2020-04-27 | 2021-11-04 | Wayne R. Matson | Detection and modification of gut microbial population |
| CN112149311B (zh) * | 2020-10-12 | 2021-10-26 | 北京中恒利华石油技术研究所 | 一种基于数量规约的非线性多元统计回归测井曲线预测方法 |
| CN112843036A (zh) * | 2021-01-29 | 2021-05-28 | 中国药科大学 | β-羟基丙酮酸在制备人胰岛淀粉样多肽聚集抑制剂中的应用 |
| CN116087486B (zh) * | 2021-11-08 | 2024-02-02 | 中国医学科学院阜外医院 | 糖尿病患者早期预测心血管疾病（cvd）的生物标志物及其用途 |
| CN114324662B (zh) * | 2021-12-30 | 2022-09-16 | 中南大学 | 用于诊断或预防糖尿病的血清生物标志物的应用 |
| EP4504961A1 (en) * | 2022-04-07 | 2025-02-12 | Need4Health B.V. | Method for determining insulin dosage |
| JP7736971B2 (ja) * | 2022-10-18 | 2025-09-10 | 株式会社オルトメディコ | 糖尿病境界域者のスクリーニング方法 |
| WO2024097429A1 (en) * | 2022-11-05 | 2024-05-10 | Texas Tech University System | Methods and tools for assessing cardiometabolic health and hidden disease risk among apparently healthy individuals |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7329489B2 (en) | 2000-04-14 | 2008-02-12 | Matabolon, Inc. | Methods for drug discovery, disease treatment, and diagnosis using metabolomics |
| JP2003530130A (ja) | 2000-04-14 | 2003-10-14 | メタボロン インコーポレイテッド | メタボロミクスを使用した薬物発見、疾患の処置、及び診断のための方法 |
| EP1718327B1 (en) * | 2003-06-20 | 2015-01-07 | University of Florida | Biomarkers for differentiating between type 1 and type 2 diabetes |
| US7682782B2 (en) | 2004-10-29 | 2010-03-23 | Affymetrix, Inc. | System, method, and product for multiple wavelength detection using single source excitation |
| US8119358B2 (en) * | 2005-10-11 | 2012-02-21 | Tethys Bioscience, Inc. | Diabetes-related biomarkers and methods of use thereof |
| WO2007110357A2 (en) * | 2006-03-24 | 2007-10-04 | Metanomics Gmbh | Means and method for diagnosing diabetes |
| MX2010000414A (es) * | 2007-07-17 | 2010-04-01 | Metabolon Inc | Biomarcadores para prediabetes, enfermedades cardiovasculares y otros trastornos relacionados con sindrome metabolico, y metodos de uso de los mismos. |
| WO2010005982A2 (en) * | 2008-07-07 | 2010-01-14 | The General Hospital Corporation | Multiplexed biomarkers of insulin resistance |
| WO2010007106A1 (en) * | 2008-07-15 | 2010-01-21 | Metanomics Health Gmbh | Means and methods diagnosing gastric bypass and conditions related thereto |
| JP2012522989A (ja) * | 2009-03-31 | 2012-09-27 | メタボロン インコーポレイテッド | インスリン抵抗性に関連するバイオマーカー、及びそれを使用する方法 |
| US8367418B2 (en) | 2009-10-23 | 2013-02-05 | Therasyn Sensors, Inc. | Method and system to provide personalized pharmaceutical compositions and dosages |
| EP2494364A1 (en) * | 2009-10-29 | 2012-09-05 | Tethys Bioscience, Inc. | Protein and lipid biomarkers providing consistent improvement to the prediction of type 2 diabetes |
| WO2013059234A1 (en) * | 2011-10-18 | 2013-04-25 | Metabolon, Inc. | Biomarkers for amyotrophic lateral sclerosis and methods using the same |
| EP2776832A4 (en) * | 2011-11-11 | 2015-06-03 | Metabolon Inc | BIOMARKER FOR BUBBLE CANCER AND METHOD FOR ITS USE |
| EP2788763A4 (en) * | 2011-12-09 | 2015-10-07 | Metabolon Inc | BIOMARKERS FOR KIDNEY CANCER AND METHOD FOR USE THEREOF |
-
2014
- 2014-01-16 US US14/763,962 patent/US9910047B2/en active Active
- 2014-01-16 JP JP2015556042A patent/JP6404834B2/ja active Active
- 2014-01-16 EP EP17209399.9A patent/EP3321686B1/en active Active
- 2014-01-16 ES ES14746017.4T patent/ES2669620T3/es active Active
- 2014-01-16 WO PCT/US2014/011759 patent/WO2014120449A1/en not_active Ceased
- 2014-01-16 EP EP14746017.4A patent/EP2951313B1/en active Active
- 2014-01-16 ES ES17209399T patent/ES2987582T3/es active Active
-
2018
- 2018-01-16 US US15/872,373 patent/US20180203021A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2951313B1 (en) | 2018-03-07 |
| US20150362510A1 (en) | 2015-12-17 |
| EP3321686B1 (en) | 2024-03-13 |
| EP2951313A4 (en) | 2016-11-02 |
| JP2016509222A (ja) | 2016-03-24 |
| WO2014120449A1 (en) | 2014-08-07 |
| US20180203021A1 (en) | 2018-07-19 |
| US9910047B2 (en) | 2018-03-06 |
| HK1217516A1 (en) | 2017-01-13 |
| EP3321686A1 (en) | 2018-05-16 |
| ES2987582T3 (es) | 2024-11-15 |
| EP2951313A1 (en) | 2015-12-09 |
| JP6404834B2 (ja) | 2018-10-17 |
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