ES2666397T3 - Activación de CD89 en terapia - Google Patents
Activación de CD89 en terapia Download PDFInfo
- Publication number
- ES2666397T3 ES2666397T3 ES11794757.2T ES11794757T ES2666397T3 ES 2666397 T3 ES2666397 T3 ES 2666397T3 ES 11794757 T ES11794757 T ES 11794757T ES 2666397 T3 ES2666397 T3 ES 2666397T3
- Authority
- ES
- Spain
- Prior art keywords
- therapy
- activation
- molecule
- activating molecule
- activating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/283—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against Fc-receptors, e.g. CD16, CD32, CD64
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/75—Agonist effect on antigen
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Endocrinology (AREA)
- Pulmonology (AREA)
- Child & Adolescent Psychology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Una molécula activadora de CD89 para su uso en el tratamiento de una afección inflamatoria o un trastorno autoinmunitario, mediante la inducción de la apoptosis en neutrófilos, donde la molécula activadora de CD89 es una molécula que comprende Fc alfa, que se administra como una solución estéril.
Description
Claims (1)
-
imagen1
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP10194942 | 2010-12-14 | ||
EP10194942A EP2465536A1 (en) | 2010-12-14 | 2010-12-14 | CD89 activation in therapy |
PCT/EP2011/072711 WO2012080306A1 (en) | 2010-12-14 | 2011-12-14 | Cd89 activation in therapy |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2666397T3 true ES2666397T3 (es) | 2018-05-04 |
Family
ID=43952841
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES11794757.2T Active ES2666397T3 (es) | 2010-12-14 | 2011-12-14 | Activación de CD89 en terapia |
Country Status (16)
Country | Link |
---|---|
US (2) | US9522184B2 (es) |
EP (2) | EP2465536A1 (es) |
JP (1) | JP6245986B2 (es) |
KR (1) | KR101946231B1 (es) |
CN (1) | CN103313728B (es) |
AU (1) | AU2011343392B2 (es) |
BR (1) | BR112013014669A2 (es) |
CA (1) | CA2821296A1 (es) |
DK (1) | DK2651440T3 (es) |
ES (1) | ES2666397T3 (es) |
IL (1) | IL226805B (es) |
MX (1) | MX355394B (es) |
NZ (1) | NZ610891A (es) |
RU (1) | RU2640082C2 (es) |
SG (1) | SG190917A1 (es) |
WO (1) | WO2012080306A1 (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2465536A1 (en) * | 2010-12-14 | 2012-06-20 | CSL Behring AG | CD89 activation in therapy |
EP2636681A1 (en) | 2012-03-09 | 2013-09-11 | CSL Behring AG | Process for enriching IgA |
EP2636684A1 (en) | 2012-03-09 | 2013-09-11 | CSL Behring AG | Prevention of infection |
SG11201404958SA (en) | 2012-03-09 | 2014-11-27 | Csl Behring Ag | Compositions comprising secretory - like immunoglobulins |
US9458230B2 (en) | 2013-01-04 | 2016-10-04 | Wisconsin Alumni Research Foundation | Secretory IGA compositions, methods of making and methods of use thereof |
US9468674B2 (en) * | 2013-09-24 | 2016-10-18 | Wisconsin Alumni Research Foundation | Methods of use of secretory IgA |
US10668147B2 (en) | 2015-03-25 | 2020-06-02 | Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung E.V. | Anti-CD89 cytotoxic complex |
CN111278862A (zh) | 2017-09-21 | 2020-06-12 | Umc乌德勒支控股有限公司 | 用于治疗成神经细胞瘤的抗gd2抗体 |
KR20220004979A (ko) | 2019-03-27 | 2022-01-12 | 유엠씨 우트레크트 홀딩 비.브이. | 조작된 iga 항체 및 사용 방법 |
US20220133761A1 (en) * | 2020-11-04 | 2022-05-05 | Washington State University | Neutrophil apoptosis induced by nanoparticles for treating inflammatory diseases |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ269735A (en) * | 1993-07-30 | 1998-01-26 | Oravax Inc | Monoclonal iga antibody against respiratory syncytial virus (rsv) |
US5922845A (en) * | 1996-07-11 | 1999-07-13 | Medarex, Inc. | Therapeutic multispecific compounds comprised of anti-Fcα receptor antibodies |
WO1998057993A1 (en) * | 1997-06-19 | 1998-12-23 | The Regents Of The University Of California | Secretory immunoglobulin produced by single cells and methods for making and using same |
CA2437814C (en) * | 2001-02-12 | 2008-05-13 | Medarex, Inc. | Human monoclonal antibodies to fc alpha receptor (cd89) |
US6932967B2 (en) * | 2001-03-22 | 2005-08-23 | Michael R. Simon | Human medical treatment by aerosol inhalation of immunoglobulin A |
US20060165675A1 (en) * | 2002-08-02 | 2006-07-27 | Richman-Eisenstat Janice Beth | Modulation of mesenchymal cells via iga-receptors |
AU2004282984B2 (en) * | 2003-11-13 | 2011-07-14 | Hanmi Science Co., Ltd. | Protein complex using immunoglobulin fragment andmethod for the preparation thereof |
EP2465536A1 (en) * | 2010-12-14 | 2012-06-20 | CSL Behring AG | CD89 activation in therapy |
-
2010
- 2010-12-14 EP EP10194942A patent/EP2465536A1/en not_active Withdrawn
-
2011
- 2011-12-14 KR KR1020137018188A patent/KR101946231B1/ko active IP Right Grant
- 2011-12-14 NZ NZ610891A patent/NZ610891A/en not_active IP Right Cessation
- 2011-12-14 ES ES11794757.2T patent/ES2666397T3/es active Active
- 2011-12-14 SG SG2013041322A patent/SG190917A1/en unknown
- 2011-12-14 JP JP2013543743A patent/JP6245986B2/ja active Active
- 2011-12-14 EP EP11794757.2A patent/EP2651440B1/en active Active
- 2011-12-14 WO PCT/EP2011/072711 patent/WO2012080306A1/en active Application Filing
- 2011-12-14 CA CA2821296A patent/CA2821296A1/en not_active Abandoned
- 2011-12-14 BR BR112013014669A patent/BR112013014669A2/pt not_active Application Discontinuation
- 2011-12-14 CN CN201180060034.4A patent/CN103313728B/zh active Active
- 2011-12-14 DK DK11794757.2T patent/DK2651440T3/en active
- 2011-12-14 RU RU2013132220A patent/RU2640082C2/ru active
- 2011-12-14 US US13/991,811 patent/US9522184B2/en active Active
- 2011-12-14 AU AU2011343392A patent/AU2011343392B2/en active Active
- 2011-12-14 MX MX2013006589A patent/MX355394B/es active IP Right Grant
-
2013
- 2013-06-06 IL IL22680513A patent/IL226805B/en active IP Right Grant
-
2016
- 2016-12-19 US US15/384,140 patent/US20170166640A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP2651440B1 (en) | 2018-01-24 |
US20170166640A1 (en) | 2017-06-15 |
NZ610891A (en) | 2015-05-29 |
MX355394B (es) | 2018-04-18 |
RU2013132220A (ru) | 2015-01-20 |
DK2651440T3 (en) | 2018-05-07 |
MX2013006589A (es) | 2014-02-06 |
EP2651440A1 (en) | 2013-10-23 |
RU2640082C2 (ru) | 2017-12-26 |
AU2011343392B2 (en) | 2017-01-05 |
EP2465536A1 (en) | 2012-06-20 |
SG190917A1 (en) | 2013-07-31 |
KR20140048077A (ko) | 2014-04-23 |
WO2012080306A1 (en) | 2012-06-21 |
BR112013014669A2 (pt) | 2016-11-29 |
CA2821296A1 (en) | 2012-06-21 |
KR101946231B1 (ko) | 2019-02-12 |
US20130302345A1 (en) | 2013-11-14 |
CN103313728A (zh) | 2013-09-18 |
IL226805B (en) | 2019-10-31 |
JP6245986B2 (ja) | 2017-12-13 |
CN103313728B (zh) | 2016-11-09 |
US9522184B2 (en) | 2016-12-20 |
JP2014502962A (ja) | 2014-02-06 |
AU2011343392A1 (en) | 2013-05-02 |
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