ES2665917T3 - Endoxifeno para su uso en el tratamiento del cáncer - Google Patents
Endoxifeno para su uso en el tratamiento del cáncer Download PDFInfo
- Publication number
- ES2665917T3 ES2665917T3 ES07871563.8T ES07871563T ES2665917T3 ES 2665917 T3 ES2665917 T3 ES 2665917T3 ES 07871563 T ES07871563 T ES 07871563T ES 2665917 T3 ES2665917 T3 ES 2665917T3
- Authority
- ES
- Spain
- Prior art keywords
- endoxifene
- cancer treatment
- endoxyphene
- cancer
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dispersion Chemistry (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Pyrane Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86042006P | 2006-11-21 | 2006-11-21 | |
| US860420P | 2006-11-21 | ||
| US86078806P | 2006-11-22 | 2006-11-22 | |
| US860788P | 2006-11-22 | ||
| PCT/US2007/085443 WO2008070463A2 (en) | 2006-11-21 | 2007-11-21 | Endoxifen methods and compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2665917T3 true ES2665917T3 (es) | 2018-04-30 |
Family
ID=39492975
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES07871563.8T Active ES2665917T3 (es) | 2006-11-21 | 2007-11-21 | Endoxifeno para su uso en el tratamiento del cáncer |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US9333190B2 (cs) |
| EP (1) | EP2101731B1 (cs) |
| JP (1) | JP2010510327A (cs) |
| CA (1) | CA2669913C (cs) |
| DK (1) | DK2101731T3 (cs) |
| ES (1) | ES2665917T3 (cs) |
| HU (1) | HUE037109T2 (cs) |
| IN (1) | IN2014MN00139A (cs) |
| PL (1) | PL2101731T3 (cs) |
| PT (1) | PT2101731T (cs) |
| WO (1) | WO2008070463A2 (cs) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUE037109T2 (hu) | 2006-11-21 | 2018-08-28 | Jina Pharmaceuticals Inc | Endoxifén rák kezelésében történõ alkalmazásra |
| US20090291134A1 (en) * | 2006-11-21 | 2009-11-26 | Jina Pharmaceuticals, Inc. | Endoxifen methods and compositions in the treatment of psychiatric and neurodegenerative diseases |
| PL3202420T3 (pl) * | 2008-12-11 | 2020-07-13 | Besins Healthcare Luxembourg Sarl | Transdermalne kompozycje farmaceutyczne zawierające SERM |
| MX345102B (es) | 2011-04-28 | 2017-01-16 | Oncopeptides Ab | Preparacion liofilizada de dipeptidos citotoxicos. |
| EP2668945A1 (de) | 2012-06-01 | 2013-12-04 | Bayer Technology Services GmbH | Genotyp- bzw. Phänotyp-basierte Arzeimittelformulierungen |
| KR102205592B1 (ko) * | 2012-10-26 | 2021-01-20 | 온코펩타이드즈 아베 | 멜팔란 플루펜아미드의 동결건조 제제 |
| US20180200206A1 (en) * | 2015-07-14 | 2018-07-19 | Atossa Genetics Inc. | Transpapillary methods and compositions for treating breast disorders |
| DE102015222031A1 (de) | 2015-11-10 | 2017-05-11 | Robert Bosch Gesellschaft Für Medizinische Forschung Mbh | Synthese von (Z)-Endoxifenhydrochlorid |
| US20170304232A1 (en) * | 2016-04-20 | 2017-10-26 | Northwestern University | Endoxifen For Local Transdermal Therapy To The Breast |
| AU2018329182A1 (en) * | 2017-09-11 | 2020-03-19 | Atossa Therapeutics, Inc. | Topical compositions and methods for treatment |
| IL319158A (en) | 2017-09-11 | 2025-04-01 | Atossa Therapeutics Inc | Methods for preparing and using endoxifen |
| KR20220042352A (ko) * | 2019-07-03 | 2022-04-05 | 아토사 테라퓨틱스, 인크. | 엔독시펜의 서방성 조성물 |
| US11291640B2 (en) | 2020-04-10 | 2022-04-05 | Jina Pharmaceuticals, Inc. | Endoxifen for the treatment of bipolar I disorder |
| WO2021205404A1 (en) | 2020-04-10 | 2021-10-14 | Jina Pharmaceuticals, Inc. | Endoxifen for the treatment of bipolar i disorder |
| US20220296518A1 (en) * | 2021-03-18 | 2022-09-22 | National Taiwan University | Lipid-based nanoparticle delivery system for hydrophilic charged compound |
| KR20240146667A (ko) | 2022-01-12 | 2024-10-08 | 아토사 테라퓨틱스, 인크. | (z)-엔독시펜의 조성물 및 그의 농축 방법 |
| US20250281414A1 (en) * | 2022-04-26 | 2025-09-11 | Atossa Therapeutics, Inc. | High dose endoxifen formulations and methods of use |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2817157A1 (de) * | 1978-04-17 | 1979-10-25 | Schering Ag | Verwendung von antioestrogenen und antigonadotrop wirkenden antiandrogenen zur prophylaxe und therapie der prostatahyperplasie |
| EP1138319A3 (en) * | 1994-08-04 | 2003-03-19 | Elan Drug Delivery Limited | Solid delivery systems for controlled release of molecules incorporated therein and methods of making same |
| US6290991B1 (en) | 1994-12-02 | 2001-09-18 | Quandrant Holdings Cambridge Limited | Solid dose delivery vehicle and methods of making same |
| AU736301B2 (en) * | 1996-05-01 | 2001-07-26 | Imarx Therapeutics, Inc. | Methods for delivering compounds into a cell |
| US6090407A (en) * | 1997-09-23 | 2000-07-18 | Research Development Foundation | Small particle liposome aerosols for delivery of anti-cancer drugs |
| US7968532B2 (en) | 2003-12-15 | 2011-06-28 | Besins Healthcare Luxembourg | Treatment of gynecomastia with 4-hydroxy tamoxifen |
| HUE031951T2 (en) | 2006-10-10 | 2017-08-28 | Jina Pharmaceuticals Inc | Aqueous systems for lipid-based drug compounds; preparations, processes and their use |
| WO2008048194A1 (en) | 2006-10-20 | 2008-04-24 | Yesilogluj Aysegul Yildiz | Use of the protein kinase c inhibitor tamoxifen for the treatment of bipolar disorder |
| CA2669355C (en) | 2006-11-06 | 2012-10-30 | Jina Pharmaceuticals, Inc. | Guggulphospholipid methods and compositions |
| US20090291134A1 (en) | 2006-11-21 | 2009-11-26 | Jina Pharmaceuticals, Inc. | Endoxifen methods and compositions in the treatment of psychiatric and neurodegenerative diseases |
| HUE037109T2 (hu) | 2006-11-21 | 2018-08-28 | Jina Pharmaceuticals Inc | Endoxifén rák kezelésében történõ alkalmazásra |
| JP5720881B2 (ja) | 2011-01-31 | 2015-05-20 | 東芝ライテック株式会社 | Ｌｅｄランプ点灯装置および照明装置 |
-
2007
- 2007-11-21 HU HUE07871563A patent/HUE037109T2/hu unknown
- 2007-11-21 PT PT78715638T patent/PT2101731T/pt unknown
- 2007-11-21 CA CA2669913A patent/CA2669913C/en active Active
- 2007-11-21 WO PCT/US2007/085443 patent/WO2008070463A2/en active Application Filing
- 2007-11-21 IN IN139MUN2014 patent/IN2014MN00139A/en unknown
- 2007-11-21 DK DK07871563.8T patent/DK2101731T3/en active
- 2007-11-21 PL PL07871563T patent/PL2101731T3/pl unknown
- 2007-11-21 EP EP07871563.8A patent/EP2101731B1/en not_active Revoked
- 2007-11-21 ES ES07871563.8T patent/ES2665917T3/es active Active
- 2007-11-21 JP JP2009538518A patent/JP2010510327A/ja active Pending
- 2007-11-21 US US12/515,261 patent/US9333190B2/en active Active
-
2016
- 2016-04-27 US US15/139,687 patent/US10376479B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CA2669913A1 (en) | 2008-06-12 |
| IN2014MN00139A (cs) | 2015-06-19 |
| EP2101731A4 (en) | 2011-04-20 |
| PL2101731T3 (pl) | 2018-07-31 |
| CA2669913C (en) | 2012-09-18 |
| US9333190B2 (en) | 2016-05-10 |
| JP2010510327A (ja) | 2010-04-02 |
| DK2101731T3 (en) | 2018-04-16 |
| US10376479B2 (en) | 2019-08-13 |
| PT2101731T (pt) | 2018-04-18 |
| WO2008070463A9 (en) | 2008-09-18 |
| HUE037109T2 (hu) | 2018-08-28 |
| WO2008070463A3 (en) | 2008-11-06 |
| US20100112041A1 (en) | 2010-05-06 |
| EP2101731B1 (en) | 2018-01-31 |
| EP2101731A2 (en) | 2009-09-23 |
| WO2008070463A2 (en) | 2008-06-12 |
| US20160346230A1 (en) | 2016-12-01 |
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