ES2664747T3 - Antagonistas peptídicos del receptor de vasopresina-2 - Google Patents

Antagonistas peptídicos del receptor de vasopresina-2 Download PDF

Info

Publication number
ES2664747T3
ES2664747T3 ES13801742.1T ES13801742T ES2664747T3 ES 2664747 T3 ES2664747 T3 ES 2664747T3 ES 13801742 T ES13801742 T ES 13801742T ES 2664747 T3 ES2664747 T3 ES 2664747T3
Authority
ES
Spain
Prior art keywords
seq
protein
da2a
amino acid
protein according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES13801742.1T
Other languages
English (en)
Spanish (es)
Inventor
Nicolas Gilles
Denis SERVENT
Loïc QUINTON
Helen REINFRANK
Ralph WITZGALL
Bernard Mouillac
Christiane MENDRE
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universite de Liege
Universitaet Regensburg
Centre National de la Recherche Scientifique CNRS
Institut National de la Sante et de la Recherche Medicale INSERM
Commissariat a lEnergie Atomique et aux Energies Alternatives CEA
Original Assignee
Universite de Liege
Universitaet Regensburg
Centre National de la Recherche Scientifique CNRS
Commissariat a lEnergie Atomique CEA
Institut National de la Sante et de la Recherche Medicale INSERM
Commissariat a lEnergie Atomique et aux Energies Alternatives CEA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universite de Liege, Universitaet Regensburg, Centre National de la Recherche Scientifique CNRS, Commissariat a lEnergie Atomique CEA, Institut National de la Sante et de la Recherche Medicale INSERM, Commissariat a lEnergie Atomique et aux Energies Alternatives CEA filed Critical Universite de Liege
Application granted granted Critical
Publication of ES2664747T3 publication Critical patent/ES2664747T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
ES13801742.1T 2012-09-17 2013-09-17 Antagonistas peptídicos del receptor de vasopresina-2 Active ES2664747T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12306120 2012-09-17
EP12306120.2A EP2708235A1 (en) 2012-09-17 2012-09-17 Peptide antagonists of the vasopressin-2 receptor
PCT/IB2013/058615 WO2014041526A1 (en) 2012-09-17 2013-09-17 Peptide antagonists of the vasopressin-2 receptor

Publications (1)

Publication Number Publication Date
ES2664747T3 true ES2664747T3 (es) 2018-04-23

Family

ID=46963639

Family Applications (1)

Application Number Title Priority Date Filing Date
ES13801742.1T Active ES2664747T3 (es) 2012-09-17 2013-09-17 Antagonistas peptídicos del receptor de vasopresina-2

Country Status (14)

Country Link
US (1) US9631001B2 (enExample)
EP (2) EP2708235A1 (enExample)
JP (1) JP6392758B2 (enExample)
KR (1) KR102135954B1 (enExample)
CN (1) CN104684574B (enExample)
AU (1) AU2013316700B2 (enExample)
BR (1) BR112015005750B1 (enExample)
CA (1) CA2884361C (enExample)
DK (1) DK2895189T3 (enExample)
ES (1) ES2664747T3 (enExample)
MX (1) MX362664B (enExample)
NZ (1) NZ706202A (enExample)
RU (1) RU2015114320A (enExample)
WO (1) WO2014041526A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021528476A (ja) * 2018-06-28 2021-10-21 サルアクア ダイアグノスティックス， インコーポレイテッド ハプトグロビン関連タンパク質と関係する組成物および方法
EP3929209A1 (en) 2020-06-24 2021-12-29 Commissariat à l'Energie Atomique et aux Energies Alternatives Vasopressin-2 receptor antagonist peptides and uses thereof
CN115820734B (zh) * 2022-11-11 2024-12-13 北京希诺谷生物科技有限公司 中枢性尿崩症疾病模型犬的建立方法
CN116425888B (zh) * 2023-04-24 2024-11-05 徐州医科大学 一种多肽tat-v2r1c及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5663143A (en) * 1988-09-02 1997-09-02 Dyax Corp. Engineered human-derived kunitz domains that inhibit human neutrophil elastase
SE0201863D0 (en) 2002-06-18 2002-06-18 Cepep Ab Cell penetrating peptides
WO2007019267A1 (en) 2005-08-03 2007-02-15 Mineuet Therapeutics Ltd. MODULATING THE KV1.1 VOLTAGE-GATED POTASSIUM CHANNEL IN T-CELLS FOR REGULATING THE SYNTHESIS AND SECRETION OF TUMOR NECROSIS FACTOR α (TNF-α) AND TREATING HUMAN DISEASES OR INJURIES MEDIATED BY DETRIMENTALLY HIGH OR LOW LEVELS OF TNF-α
US8343760B2 (en) * 2008-06-05 2013-01-01 University Of Maryland, Baltimore p53 activator peptides

Also Published As

Publication number Publication date
CN104684574A (zh) 2015-06-03
AU2013316700B2 (en) 2017-10-12
EP2708235A1 (en) 2014-03-19
KR20150070172A (ko) 2015-06-24
JP6392758B2 (ja) 2018-09-19
BR112015005750A8 (pt) 2018-04-17
BR112015005750B1 (pt) 2022-08-16
WO2014041526A1 (en) 2014-03-20
EP2895189A1 (en) 2015-07-22
CN104684574B (zh) 2018-08-31
RU2015114320A (ru) 2016-11-10
DK2895189T3 (en) 2018-04-16
CA2884361A1 (en) 2014-03-20
MX362664B (es) 2019-01-31
BR112015005750A2 (pt) 2017-12-12
KR102135954B1 (ko) 2020-07-21
JP2016500001A (ja) 2016-01-07
EP2895189B1 (en) 2018-01-10
US9631001B2 (en) 2017-04-25
CA2884361C (en) 2022-03-22
AU2013316700A1 (en) 2015-04-09
US20150252086A1 (en) 2015-09-10
NZ706202A (en) 2018-06-29
MX2015003225A (es) 2015-11-16

Similar Documents

Publication Publication Date Title
ES2605015T3 (es) Métodos para modular respuestas neuronales
US20110245167A1 (en) NaK-ATPase-Derived Peptide SRC Inhibitors and Ouabain Antagonists and Uses Thereof
BRPI0619023A2 (pt) composto que inibe a ativação do complemento
ES2664747T3 (es) Antagonistas peptídicos del receptor de vasopresina-2
US20180312539A1 (en) Methods for preparing high throughput peptidomimetics, orally bioavailable drugs and compositions containing same
JP2021515759A (ja) コンプスタチン類似体及びその医療用途
US20180028595A1 (en) Compositions and methods for regulating blood pressure
CA2813802C (en) Single chain relaxin polypeptides
CN103038248B (zh) Rhamm结合肽
ES2796857T3 (es) Polipéptidos y usos de los mismos para reducir la motilidad celular mediada por CD95
WO2023203127A1 (en) Alphabody-based degrader molecules
Hoppmann et al. Expression, purification and fluorine-18 radiolabeling of recombinant S100 proteins—potential probes for molecular imaging of receptor for advanced glycation endproducts (RAGE) in vivo
EP3280801B1 (en) Internalisation of human htra1 and cargo proteins into mammalian cells
JP7617958B2 (ja) バソプレシン２受容体アンタゴニストペプチド及びその使用
Lee Development of the novel amylin receptor activators with nanomolar potency by peptide mutagenesis
Sabatier et al. Animal Toxins
Bower Molecular Determinants of Amylin Receptor Agonism
Chen Novel pharmacology and distinct protein interactions of human alpha (1)-adrenergic receptor subtypes
Remus Protein interactions of the inositol 1, 4, 5 tris phosphate receptor