ES2657927T3 - Métodos de detección de aneuploidía en embriones humanos - Google Patents

Métodos de detección de aneuploidía en embriones humanos Download PDF

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Publication number
ES2657927T3
ES2657927T3 ES12749372.4T ES12749372T ES2657927T3 ES 2657927 T3 ES2657927 T3 ES 2657927T3 ES 12749372 T ES12749372 T ES 12749372T ES 2657927 T3 ES2657927 T3 ES 2657927T3
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Prior art keywords
embryo
cytokinesis
cell
embryos
fragmentation
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ES12749372.4T
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English (en)
Spanish (es)
Inventor
Shawn L. CHAVEZ
Kevin E. Loewke
Barry Behr
Renee A. Reijo Pera
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Leland Stanford Junior University
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Leland Stanford Junior University
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/38Pediatrics
    • G01N2800/385Congenital anomalies
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/38Pediatrics
    • G01N2800/385Congenital anomalies
    • G01N2800/387Down syndrome; Trisomy 18; Trisomy 13

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
ES12749372.4T 2011-02-23 2012-02-23 Métodos de detección de aneuploidía en embriones humanos Active ES2657927T3 (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161445863P 2011-02-23 2011-02-23
US201161445863P 2011-02-23
US201161537336P 2011-09-21 2011-09-21
US201161537336P 2011-09-21
PCT/US2012/026328 WO2012116185A1 (en) 2011-02-23 2012-02-23 Methods of detecting aneuploidy in human embryos

Publications (1)

Publication Number Publication Date
ES2657927T3 true ES2657927T3 (es) 2018-03-07

Family

ID=46721231

Family Applications (1)

Application Number Title Priority Date Filing Date
ES12749372.4T Active ES2657927T3 (es) 2011-02-23 2012-02-23 Métodos de detección de aneuploidía en embriones humanos

Country Status (12)

Country Link
US (1) US9879307B2 (enExample)
EP (1) EP2678675B1 (enExample)
JP (1) JP2014507664A (enExample)
CN (1) CN103460038A (enExample)
AU (1) AU2012220540B2 (enExample)
CA (1) CA2827945C (enExample)
DK (1) DK2678675T3 (enExample)
ES (1) ES2657927T3 (enExample)
HU (1) HUE036056T2 (enExample)
IL (1) IL228066B (enExample)
PT (1) PT2678675T (enExample)
WO (1) WO2012116185A1 (enExample)

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US9404908B2 (en) * 2013-04-29 2016-08-02 The Board of Truestees of the Leland Stanford Junior University Non-invasive imaging to the blastocyst stage for the detection of human embryonic aneuploidy
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US11494578B1 (en) * 2015-09-21 2022-11-08 Ares Trading S.A. Systems and methods for automated assessment of embryo quality using image based features
CN109829898B (zh) * 2019-01-17 2023-05-16 柳州康云互联科技有限公司 一种用于互联网检测中基于神经网络的测量检测系统及方法
CN110363218B (zh) * 2019-06-06 2023-07-11 张孝东 一种胚胎无创评估方法及装置
CA3144694A1 (en) 2019-07-25 2021-01-28 Jose A. Horcajadas Identification of viable human embryos
CN112582022B (zh) * 2020-07-21 2021-11-23 序康医疗科技(苏州)有限公司 用于无创胚胎移植优先级评级的系统和方法
JP2023537340A (ja) * 2020-07-31 2023-08-31 シャフリヤール ケイ. カヴォッシ 胚をスクリーニングするための方法
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CN113744892A (zh) * 2021-09-02 2021-12-03 上海宝藤生物医药科技股份有限公司 胚胎整倍性预测方法、装置、电子设备及存储介质
CN114067317B (zh) * 2021-11-24 2025-03-18 北京航空航天大学合肥创新研究院(北京航空航天大学合肥研究生院) 染色体异常事件的检测方法、装置、电子设备及介质
CN115641364B (zh) * 2022-12-22 2023-03-21 武汉互创联合科技有限公司 基于胚胎动力学参数的胚胎分裂周期智能预测系统及方法
CN118397621B (zh) * 2024-06-26 2024-08-27 武汉互创联合科技有限公司 一种基于光流特征融合的多焦距胚胎细胞原核检测方法

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Also Published As

Publication number Publication date
JP2014507664A (ja) 2014-03-27
EP2678675A1 (en) 2014-01-01
HUE036056T2 (hu) 2018-06-28
EP2678675B1 (en) 2017-10-11
CN103460038A (zh) 2013-12-18
AU2012220540A1 (en) 2013-09-12
EP2678675A4 (en) 2015-04-01
DK2678675T3 (en) 2018-01-15
PT2678675T (pt) 2018-02-07
IL228066A0 (en) 2013-09-30
US9879307B2 (en) 2018-01-30
US20140087376A1 (en) 2014-03-27
CA2827945C (en) 2021-10-12
AU2012220540B2 (en) 2016-11-10
CA2827945A1 (en) 2012-08-30
IL228066B (en) 2019-02-28
WO2012116185A1 (en) 2012-08-30

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