ES2654674T3 - Método para seleccionar compuestos usando membrana de STIM1 - Google Patents
Método para seleccionar compuestos usando membrana de STIM1 Download PDFInfo
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- ES2654674T3 ES2654674T3 ES14290232.9T ES14290232T ES2654674T3 ES 2654674 T3 ES2654674 T3 ES 2654674T3 ES 14290232 T ES14290232 T ES 14290232T ES 2654674 T3 ES2654674 T3 ES 2654674T3
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- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/10—Screening for compounds of potential therapeutic value involving cells
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/10—Musculoskeletal or connective tissue disorders
- G01N2800/101—Diffuse connective tissue disease, e.g. Sjögren, Wegener's granulomatosis
- G01N2800/104—Lupus erythematosus [SLE]
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- Immunology (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14290232.9A EP2982982B1 (en) | 2014-08-06 | 2014-08-06 | Method of screening of compounds using membrane STIM1 |
Publications (1)
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| ES2654674T3 true ES2654674T3 (es) | 2018-02-14 |
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Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3715848A1 (en) * | 2019-03-25 | 2020-09-30 | Université de Bretagne Occidentale (U.B.O.) | Substance interacting with c terminal fragment of the stim1 fraction localized to the plasma membrane of the cells, for its use in the treatment of cancers, and in screening and diagnostic methods |
| EP3714942A1 (en) | 2019-03-25 | 2020-09-30 | Université De Bretagne Occidentale - UBO | Monoclonal antibody against stim1 |
| EP3714943A1 (en) | 2019-03-25 | 2020-09-30 | Université De Bretagne Occidentale - UBO | Monoclonal antibody against stim1 |
| US20240083990A1 (en) * | 2021-01-26 | 2024-03-14 | Universite Brest Bretagne Occidentale | Novel stim1 splicing variants and uses thereof |
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| CN101223448B (zh) * | 2005-05-20 | 2012-01-18 | 健泰科生物技术公司 | 来自自身免疫病受试者的生物学样品的预处理 |
| US20160169868A9 (en) * | 2007-05-24 | 2016-06-16 | Calcimedica, Inc. | Calcium channel proteins and uses thereof |
| WO2008148108A1 (en) * | 2007-05-24 | 2008-12-04 | Calcimedica, Inc. | Calcium channel proteins and uses thereof |
| JP5559049B2 (ja) * | 2007-07-10 | 2014-07-23 | チルドレンズ メディカル センター コーポレーション | 間質相互作用分子ノックアウトマウス及びその使用 |
| WO2009021338A1 (en) * | 2007-08-15 | 2009-02-19 | UNIVERSITé DE SHERBROOKE | Alternative splicing gene variants in cancer detection |
| US8263641B2 (en) * | 2007-09-10 | 2012-09-11 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
| EP2103311A1 (en) * | 2008-03-20 | 2009-09-23 | CSL Behring GmbH | The calcium sensor STIM1 is essential for pathological thrombus formation |
| US20120165265A1 (en) * | 2009-02-26 | 2012-06-28 | Dolmetsch Ricardo E | Calcium Signaling Modulators Involving STIM and ORAI Proteins |
| US8993612B2 (en) * | 2009-10-08 | 2015-03-31 | Rhizen Pharmaceuticals Sa | Modulators of calcium release-activated calcium channel and methods for treatment of non-small cell lung cancer |
| EP2723382A4 (en) * | 2011-08-10 | 2015-03-04 | Wilfred A Jefferies | METHOD AND COMPOSITIONS FOR MODULATING A VOLTAGE-CONTROLLED CALCIUM CHANNEL FUNCTION |
| CN102433383B (zh) * | 2011-12-19 | 2015-07-08 | 上海吉凯基因化学技术有限公司 | 人stim1基因的用途及其相关药物 |
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2014
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- 2014-08-06 ES ES14290232.9T patent/ES2654674T3/es active Active
- 2014-08-06 NO NO14290232A patent/NO2982982T3/no unknown
- 2014-08-06 PT PT142902329T patent/PT2982982T/pt unknown
- 2014-08-06 DK DK14290232.9T patent/DK2982982T3/en active
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2015
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- 2015-07-31 US US15/424,357 patent/US20170219588A1/en not_active Abandoned
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- 2015-07-31 CN CN201580042267.XA patent/CN106716130B/zh not_active Expired - Fee Related
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2019
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| CA2952159A1 (en) | 2016-02-11 |
| CN106716130A (zh) | 2017-05-24 |
| JP6861246B2 (ja) | 2021-04-21 |
| JP6754751B2 (ja) | 2020-09-16 |
| US20190154690A1 (en) | 2019-05-23 |
| JP2017531164A (ja) | 2017-10-19 |
| WO2016020274A1 (en) | 2016-02-11 |
| CN106716130B (zh) | 2019-03-29 |
| CA2952159C (en) | 2022-08-30 |
| US20170219588A1 (en) | 2017-08-03 |
| DK2982982T3 (en) | 2018-01-08 |
| JP2019214576A (ja) | 2019-12-19 |
| EP3177929B1 (en) | 2018-05-09 |
| PT2982982T (pt) | 2018-01-03 |
| CN110051836A (zh) | 2019-07-26 |
| EP3177929A1 (en) | 2017-06-14 |
| EP2982982B1 (en) | 2017-10-04 |
| PL2982982T3 (pl) | 2018-03-30 |
| EP2982982A1 (en) | 2016-02-10 |
| CN110051836B (zh) | 2023-05-26 |
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