DK2982982T3 - Method of screening compounds using membrane STIM1 - Google Patents
Method of screening compounds using membrane STIM1 Download PDFInfo
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- DK2982982T3 DK2982982T3 DK14290232.9T DK14290232T DK2982982T3 DK 2982982 T3 DK2982982 T3 DK 2982982T3 DK 14290232 T DK14290232 T DK 14290232T DK 2982982 T3 DK2982982 T3 DK 2982982T3
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- cells
- stim1
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- antibody
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Classifications
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
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- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- A—HUMAN NECESSITIES
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- A61P35/02—Antineoplastic agents specific for leukemia
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- A—HUMAN NECESSITIES
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
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- A—HUMAN NECESSITIES
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- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A61K2039/507—Comprising a combination of two or more separate antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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Landscapes
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- Mycology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14290232.9A EP2982982B1 (en) | 2014-08-06 | 2014-08-06 | Method of screening of compounds using membrane STIM1 |
Publications (1)
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|---|---|
| DK2982982T3 true DK2982982T3 (en) | 2018-01-08 |
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| EP (2) | EP2982982B1 (enExample) |
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| PL (1) | PL2982982T3 (enExample) |
| PT (1) | PT2982982T (enExample) |
| WO (1) | WO2016020274A1 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3715848A1 (en) * | 2019-03-25 | 2020-09-30 | Université de Bretagne Occidentale (U.B.O.) | Substance interacting with c terminal fragment of the stim1 fraction localized to the plasma membrane of the cells, for its use in the treatment of cancers, and in screening and diagnostic methods |
| EP3714942A1 (en) | 2019-03-25 | 2020-09-30 | Université De Bretagne Occidentale - UBO | Monoclonal antibody against stim1 |
| EP3714943A1 (en) | 2019-03-25 | 2020-09-30 | Université De Bretagne Occidentale - UBO | Monoclonal antibody against stim1 |
| US20240083990A1 (en) * | 2021-01-26 | 2024-03-14 | Universite Brest Bretagne Occidentale | Novel stim1 splicing variants and uses thereof |
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| CN101223448B (zh) * | 2005-05-20 | 2012-01-18 | 健泰科生物技术公司 | 来自自身免疫病受试者的生物学样品的预处理 |
| US20160169868A9 (en) * | 2007-05-24 | 2016-06-16 | Calcimedica, Inc. | Calcium channel proteins and uses thereof |
| WO2008148108A1 (en) * | 2007-05-24 | 2008-12-04 | Calcimedica, Inc. | Calcium channel proteins and uses thereof |
| JP5559049B2 (ja) * | 2007-07-10 | 2014-07-23 | チルドレンズ メディカル センター コーポレーション | 間質相互作用分子ノックアウトマウス及びその使用 |
| WO2009021338A1 (en) * | 2007-08-15 | 2009-02-19 | UNIVERSITé DE SHERBROOKE | Alternative splicing gene variants in cancer detection |
| US8263641B2 (en) * | 2007-09-10 | 2012-09-11 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
| EP2103311A1 (en) * | 2008-03-20 | 2009-09-23 | CSL Behring GmbH | The calcium sensor STIM1 is essential for pathological thrombus formation |
| US20120165265A1 (en) * | 2009-02-26 | 2012-06-28 | Dolmetsch Ricardo E | Calcium Signaling Modulators Involving STIM and ORAI Proteins |
| US8993612B2 (en) * | 2009-10-08 | 2015-03-31 | Rhizen Pharmaceuticals Sa | Modulators of calcium release-activated calcium channel and methods for treatment of non-small cell lung cancer |
| EP2723382A4 (en) * | 2011-08-10 | 2015-03-04 | Wilfred A Jefferies | METHOD AND COMPOSITIONS FOR MODULATING A VOLTAGE-CONTROLLED CALCIUM CHANNEL FUNCTION |
| CN102433383B (zh) * | 2011-12-19 | 2015-07-08 | 上海吉凯基因化学技术有限公司 | 人stim1基因的用途及其相关药物 |
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2014
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- 2014-08-06 NO NO14290232A patent/NO2982982T3/no unknown
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2015
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- 2015-07-31 US US15/424,357 patent/US20170219588A1/en not_active Abandoned
- 2015-07-31 CN CN201910160451.4A patent/CN110051836B/zh active Active
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2019
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Also Published As
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| NO2982982T3 (enExample) | 2018-03-03 |
| CA2952159A1 (en) | 2016-02-11 |
| CN106716130A (zh) | 2017-05-24 |
| JP6861246B2 (ja) | 2021-04-21 |
| JP6754751B2 (ja) | 2020-09-16 |
| US20190154690A1 (en) | 2019-05-23 |
| JP2017531164A (ja) | 2017-10-19 |
| WO2016020274A1 (en) | 2016-02-11 |
| CN106716130B (zh) | 2019-03-29 |
| CA2952159C (en) | 2022-08-30 |
| US20170219588A1 (en) | 2017-08-03 |
| JP2019214576A (ja) | 2019-12-19 |
| EP3177929B1 (en) | 2018-05-09 |
| PT2982982T (pt) | 2018-01-03 |
| CN110051836A (zh) | 2019-07-26 |
| EP3177929A1 (en) | 2017-06-14 |
| EP2982982B1 (en) | 2017-10-04 |
| ES2654674T3 (es) | 2018-02-14 |
| PL2982982T3 (pl) | 2018-03-30 |
| EP2982982A1 (en) | 2016-02-10 |
| CN110051836B (zh) | 2023-05-26 |
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