ES265398A1 - A procedure for preparing hydroxidiamins (Machine-translation by Google Translate, not legally binding) - Google Patents

A procedure for preparing hydroxidiamins (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES265398A1
ES265398A1 ES0265398A ES265398A ES265398A1 ES 265398 A1 ES265398 A1 ES 265398A1 ES 0265398 A ES0265398 A ES 0265398A ES 265398 A ES265398 A ES 265398A ES 265398 A1 ES265398 A1 ES 265398A1
Authority
ES
Spain
Prior art keywords
group
see formula
formula
alcoholic
condensation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0265398A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26709649&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES265398(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of ES265398A1 publication Critical patent/ES265398A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
    • C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
    • C07C215/14—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic the nitrogen atom of the amino group being further bound to hydrocarbon groups substituted by amino groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/04—Saturated ethers
    • C07C43/12—Saturated ethers containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D203/08—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom
    • C07D203/12—Radicals substituted by nitrogen atoms not forming part of a nitro radical

Abstract

A procedure for preparing hydroxy diamines of the following general formula **(See formula)** in which R1 is the group ** (see formula) ** in which R is a lower alcoholic, R2 and R3 are the same or different and are hydrogen atoms, lower alcohol groups or lower hydroxyalkyl groups, R4 is a lower alcohol group or lower hydroxyalkyl, X is an alcoholylene substituted or not substituted by a lower alcohol, having two or three carbon atoms and at least one of these carbon atoms forming a methylene group in the chain, and its non-toxic addition salts, characterized by (a) Condense a compound of the general formula **(See formula)** wherein A is a halogen atom, a hydroxyl group, an alcoholic or aryl sulfonic ester, or a quaternary ammonium group; or A is a carbonyl oxygen, in which case one or more of the groups on the carbon atom attached to A may be missing and be added during the course of condensation or at a later stage in the sequence; or A forms an oxirane ring with the carbon atom attached to B, in which case B disappears; or in which B and the carbon atom to which it is attached form a hydroxymethylene group or a group convertible thereto, with a compound of the formula **(See formula)** in which D is ** (see formula) **, or a group convertible in it, in the course of condensation or later and in which the radical ** (see formula) ** can be a heterocyclic group, in whose case H disappears and in which the radical ** (see formula) ** can be formed in the course of condensation, and in which the radicals ** (see formula) ** (or the group converted to it) of compounds II and III that undergo condensation can be exchanged, to form an amine of the general formula **(See formula)** in which X, R, R2, R3, R4 are as defined before and, b) when it is required to treat the compound IV to convert D to ** (see formula) ** and/or form the hydroxymethylene group and, c) if desired, alcoholic to convert R2, R3 and/or R4 of hydrogen in an alcoholic or hydroxy-alcoholic group and d) if desired, form the non-toxic addition salts of the compounds of formula I. (Machine-translation by Google Translate, not legally binding)
ES0265398A 1960-06-02 1961-03-04 A procedure for preparing hydroxidiamins (Machine-translation by Google Translate, not legally binding) Expired ES265398A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3339960A 1960-06-02 1960-06-02
US7703460A 1960-12-20 1960-12-20

Publications (1)

Publication Number Publication Date
ES265398A1 true ES265398A1 (en) 1961-09-01

Family

ID=26709649

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0265398A Expired ES265398A1 (en) 1960-06-02 1961-03-04 A procedure for preparing hydroxidiamins (Machine-translation by Google Translate, not legally binding)

Country Status (8)

Country Link
CH (1) CH449652A (en)
DE (1) DE1251770B (en)
DK (1) DK114559B (en)
ES (1) ES265398A1 (en)
FI (1) FI40635B (en)
FR (2) FR1555452A (en)
GB (1) GB961317A (en)
NL (2) NL261710A (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1768612A1 (en) * 1968-06-06 1971-11-18 Zoja Lab Chim Farm Process for the preparation of very pure, pharmaceutically suitable right-handed 2,2 '- (AEthylenediimine) -di-1-butanol dihydrochloride
CH514519A (en) * 1969-04-10 1971-10-31 Crc Ricerca Chim 2-amino-alkanol derivs prepn - anti tubercular drugs
US4430455A (en) * 1981-03-09 1984-02-07 Abbott Laboratories N'-(2-Hydroxyalkyl)-N, N, N'-trimethyl-propylene diamines as catalysts for polyurethane foams
DE3836021A1 (en) * 1988-10-22 1990-05-03 Boehringer Mannheim Gmbh MEDICINAL PRODUCT CONTAINING NITROXYALKYLAMINE WITH AMIDE FUNCTION AND METHOD FOR PRODUCING THESE COMPOUNDS
US7456222B2 (en) 2002-05-17 2008-11-25 Sequella, Inc. Anti tubercular drug: compositions and methods
CN101404986B (en) 2002-05-17 2011-09-28 赛奎拉公司 Methods of use and compositions for the diagnosis and treatment of infectious disease
US20040033986A1 (en) 2002-05-17 2004-02-19 Protopopova Marina Nikolaevna Anti tubercular drug: compositions and methods
WO2005034857A2 (en) 2003-09-05 2005-04-21 Sequella, Inc. Methods and compositions comprising diamines as new anti-tubercular therapeutics

Also Published As

Publication number Publication date
CH449652A (en) 1968-01-15
GB961317A (en)
FI40635B (en) 1968-12-31
NL261710A (en)
NL112366C (en)
FR967M (en) 1961-11-27
FR1555452A (en) 1969-01-31
DK114559B (en) 1969-07-14
DE1251770B (en) 1967-10-12

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