ES265398A1 - A procedure for preparing hydroxidiamins (Machine-translation by Google Translate, not legally binding) - Google Patents
A procedure for preparing hydroxidiamins (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES265398A1 ES265398A1 ES0265398A ES265398A ES265398A1 ES 265398 A1 ES265398 A1 ES 265398A1 ES 0265398 A ES0265398 A ES 0265398A ES 265398 A ES265398 A ES 265398A ES 265398 A1 ES265398 A1 ES 265398A1
- Authority
- ES
- Spain
- Prior art keywords
- group
- see formula
- formula
- alcoholic
- condensation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
- C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
- C07C215/14—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic the nitrogen atom of the amino group being further bound to hydrocarbon groups substituted by amino groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
- C07C43/04—Saturated ethers
- C07C43/12—Saturated ethers containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
- C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D203/08—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom
- C07D203/12—Radicals substituted by nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Compounds (AREA)
Abstract
A procedure for preparing hydroxy diamines of the following general formula **(See formula)** in which R1 is the group ** (see formula) ** in which R is a lower alcoholic, R2 and R3 are the same or different and are hydrogen atoms, lower alcohol groups or lower hydroxyalkyl groups, R4 is a lower alcohol group or lower hydroxyalkyl, X is an alcoholylene substituted or not substituted by a lower alcohol, having two or three carbon atoms and at least one of these carbon atoms forming a methylene group in the chain, and its non-toxic addition salts, characterized by (a) Condense a compound of the general formula **(See formula)** wherein A is a halogen atom, a hydroxyl group, an alcoholic or aryl sulfonic ester, or a quaternary ammonium group; or A is a carbonyl oxygen, in which case one or more of the groups on the carbon atom attached to A may be missing and be added during the course of condensation or at a later stage in the sequence; or A forms an oxirane ring with the carbon atom attached to B, in which case B disappears; or in which B and the carbon atom to which it is attached form a hydroxymethylene group or a group convertible thereto, with a compound of the formula **(See formula)** in which D is ** (see formula) **, or a group convertible in it, in the course of condensation or later and in which the radical ** (see formula) ** can be a heterocyclic group, in whose case H disappears and in which the radical ** (see formula) ** can be formed in the course of condensation, and in which the radicals ** (see formula) ** (or the group converted to it) of compounds II and III that undergo condensation can be exchanged, to form an amine of the general formula **(See formula)** in which X, R, R2, R3, R4 are as defined before and, b) when it is required to treat the compound IV to convert D to ** (see formula) ** and/or form the hydroxymethylene group and, c) if desired, alcoholic to convert R2, R3 and/or R4 of hydrogen in an alcoholic or hydroxy-alcoholic group and d) if desired, form the non-toxic addition salts of the compounds of formula I. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3339960A | 1960-06-02 | 1960-06-02 | |
US7703460A | 1960-12-20 | 1960-12-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES265398A1 true ES265398A1 (en) | 1961-09-01 |
Family
ID=26709649
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES0265398A Expired ES265398A1 (en) | 1960-06-02 | 1961-03-04 | A procedure for preparing hydroxidiamins (Machine-translation by Google Translate, not legally binding) |
Country Status (8)
Country | Link |
---|---|
CH (1) | CH449652A (en) |
DE (1) | DE1251770B (en) |
DK (1) | DK114559B (en) |
ES (1) | ES265398A1 (en) |
FI (1) | FI40635B (en) |
FR (2) | FR1555452A (en) |
GB (1) | GB961317A (en) |
NL (2) | NL261710A (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1768612A1 (en) * | 1968-06-06 | 1971-11-18 | Zoja Lab Chim Farm | Process for the preparation of very pure, pharmaceutically suitable right-handed 2,2 '- (AEthylenediimine) -di-1-butanol dihydrochloride |
CH514519A (en) * | 1969-04-10 | 1971-10-31 | Crc Ricerca Chim | 2-amino-alkanol derivs prepn - anti tubercular drugs |
US4430455A (en) * | 1981-03-09 | 1984-02-07 | Abbott Laboratories | N'-(2-Hydroxyalkyl)-N, N, N'-trimethyl-propylene diamines as catalysts for polyurethane foams |
DE3836021A1 (en) * | 1988-10-22 | 1990-05-03 | Boehringer Mannheim Gmbh | MEDICINAL PRODUCT CONTAINING NITROXYALKYLAMINE WITH AMIDE FUNCTION AND METHOD FOR PRODUCING THESE COMPOUNDS |
US20040033986A1 (en) | 2002-05-17 | 2004-02-19 | Protopopova Marina Nikolaevna | Anti tubercular drug: compositions and methods |
US7456222B2 (en) | 2002-05-17 | 2008-11-25 | Sequella, Inc. | Anti tubercular drug: compositions and methods |
US7652039B2 (en) | 2002-05-17 | 2010-01-26 | Sequella, Inc. | Methods of use and compositions for the diagnosis and treatment of infectious disease |
WO2005034857A2 (en) | 2003-09-05 | 2005-04-21 | Sequella, Inc. | Methods and compositions comprising diamines as new anti-tubercular therapeutics |
-
0
- GB GB961317D patent/GB961317A/en active Active
- NL NL112366D patent/NL112366C/xx active
- NL NL261710D patent/NL261710A/xx unknown
- DE DENDAT1251770D patent/DE1251770B/en active Pending
-
1961
- 1961-02-23 FR FR1555452D patent/FR1555452A/fr not_active Expired
- 1961-02-24 DK DK83361AA patent/DK114559B/en unknown
- 1961-02-25 FI FI0361/61A patent/FI40635B/fi active
- 1961-02-27 CH CH233761A patent/CH449652A/en unknown
- 1961-03-04 ES ES0265398A patent/ES265398A1/en not_active Expired
- 1961-03-07 FR FR854760A patent/FR967M/fr active Active
Also Published As
Publication number | Publication date |
---|---|
FR1555452A (en) | 1969-01-31 |
CH449652A (en) | 1968-01-15 |
NL261710A (en) | |
FR967M (en) | 1961-11-27 |
GB961317A (en) | |
FI40635B (en) | 1968-12-31 |
DE1251770B (en) | 1967-10-12 |
DK114559B (en) | 1969-07-14 |
NL112366C (en) |
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