CH514519A - 2-amino-alkanol derivs prepn - anti tubercular drugs - Google Patents
2-amino-alkanol derivs prepn - anti tubercular drugsInfo
- Publication number
- CH514519A CH514519A CH553569A CH553569A CH514519A CH 514519 A CH514519 A CH 514519A CH 553569 A CH553569 A CH 553569A CH 553569 A CH553569 A CH 553569A CH 514519 A CH514519 A CH 514519A
- Authority
- CH
- Switzerland
- Prior art keywords
- alkanol
- amino
- tubercular drugs
- anti tubercular
- derivs
- Prior art date
Links
- 229940124976 antitubercular drug Drugs 0.000 title abstract 2
- 239000000814 tuberculostatic agent Substances 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- AZDRQVAHHNSJOQ-UHFFFAOYSA-N alumane Chemical compound [AlH3] AZDRQVAHHNSJOQ-UHFFFAOYSA-N 0.000 abstract 1
- 229910000091 aluminium hydride Inorganic materials 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
- C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
- C07C215/14—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic the nitrogen atom of the amino group being further bound to hydrocarbon groups substituted by amino groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Title cpds. of formula (I):- (where R = 1-4C alkyl n = 2 or o) are prepd. by reduction of the carbalkoxy gps. of the corresponding methyl, ethyl or propyl acid esters, pref. with AlH3. The product may be the optical isomers, the racemate of the meso cpd. the (+)-optional is partic. active as an anti-tubercular drug.
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH553569A CH514519A (en) | 1969-04-10 | 1969-04-10 | 2-amino-alkanol derivs prepn - anti tubercular drugs |
| CA058610A CA919192A (en) | 1969-04-10 | 1969-08-05 | Method for preparing derivatives of 2-amino-butanol-1 |
| JP6825769A JPS5217005B1 (en) | 1969-04-10 | 1969-08-28 | |
| YU73470A YU34274B (en) | 1969-04-10 | 1970-03-23 | Process for preparing s-(+)-2-aminobutanol-1-derivatives |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH553569A CH514519A (en) | 1969-04-10 | 1969-04-10 | 2-amino-alkanol derivs prepn - anti tubercular drugs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH514519A true CH514519A (en) | 1971-10-31 |
Family
ID=4295233
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH553569A CH514519A (en) | 1969-04-10 | 1969-04-10 | 2-amino-alkanol derivs prepn - anti tubercular drugs |
Country Status (4)
| Country | Link |
|---|---|
| JP (1) | JPS5217005B1 (en) |
| CA (1) | CA919192A (en) |
| CH (1) | CH514519A (en) |
| YU (1) | YU34274B (en) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB961317A (en) * | 1960-06-02 |
-
1969
- 1969-04-10 CH CH553569A patent/CH514519A/en not_active IP Right Cessation
- 1969-08-05 CA CA058610A patent/CA919192A/en not_active Expired
- 1969-08-28 JP JP6825769A patent/JPS5217005B1/ja active Pending
-
1970
- 1970-03-23 YU YU73470A patent/YU34274B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| YU34274B (en) | 1979-04-30 |
| CA919192A (en) | 1973-01-16 |
| YU73470A (en) | 1978-10-31 |
| JPS5217005B1 (en) | 1977-05-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PL | Patent ceased |