ES265289A1 - New 4-substituted 1,2-diaryl-3,5-dioxo-pyrazolidines and process for their production - Google Patents
New 4-substituted 1,2-diaryl-3,5-dioxo-pyrazolidines and process for their productionInfo
- Publication number
- ES265289A1 ES265289A1 ES0265289A ES265289A ES265289A1 ES 265289 A1 ES265289 A1 ES 265289A1 ES 0265289 A ES0265289 A ES 0265289A ES 265289 A ES265289 A ES 265289A ES 265289 A1 ES265289 A1 ES 265289A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- compounds
- substituted
- salts
- pyrazolidines
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/28—Two oxygen or sulfur atoms
- C07D231/30—Two oxygen or sulfur atoms attached in positions 3 and 5
- C07D231/32—Oxygen atoms
- C07D231/34—Oxygen atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention comprises compounds of general formula: <FORM:0956850/C2/1> wherein R represents hydrogen, an alkyl or alkoxy radical having at most four carbon atoms or a halogen atom, and n is 0-4 and their salts with bases and their preparation by hydrogenolysing a compound of formula: <FORM:0956850/C2/2> wherein R1 represents an aralkyl radical. Ethers of formula II can be prepared by condensation of substituted malonic acids and their ester and halide derivatives with hydrazobenzenes of formula: <FORM:0956850/C2/3> or by introduction of the 4-substituent. Pharmaceutical preparations containing the compounds I and salts are described, particularly forms for oral (capsules, powders, tablets), parenteral (solutions) and rectal (suppositories) administration. The compounds have antiphlogistic, analgesic and antipyretic activity.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH231860A CH379512A (en) | 1960-03-01 | 1960-03-01 | Process for the preparation of new 4-substituted 1,2-diaryl-3,5-dioxo-pyrazolidines |
Publications (1)
Publication Number | Publication Date |
---|---|
ES265289A1 true ES265289A1 (en) | 1961-09-16 |
Family
ID=4230993
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES0265289A Expired ES265289A1 (en) | 1960-03-01 | 1961-02-28 | New 4-substituted 1,2-diaryl-3,5-dioxo-pyrazolidines and process for their production |
Country Status (5)
Country | Link |
---|---|
BE (1) | BE600718A (en) |
CH (1) | CH379512A (en) |
DK (1) | DK103397C (en) |
ES (1) | ES265289A1 (en) |
GB (1) | GB956850A (en) |
-
1960
- 1960-03-01 CH CH231860A patent/CH379512A/en unknown
-
1961
- 1961-02-28 GB GB728161A patent/GB956850A/en not_active Expired
- 1961-02-28 ES ES0265289A patent/ES265289A1/en not_active Expired
- 1961-02-28 DK DK88061A patent/DK103397C/en active
- 1961-02-28 BE BE600718A patent/BE600718A/en unknown
Also Published As
Publication number | Publication date |
---|---|
GB956850A (en) | 1964-04-29 |
DK103397C (en) | 1965-12-27 |
BE600718A (en) | 1961-08-28 |
CH379512A (en) | 1964-07-15 |
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