ES2636976T3 - Genes de Plasmodium malariae y Plasmodium ovale y usos de los mismos - Google Patents

Genes de Plasmodium malariae y Plasmodium ovale y usos de los mismos Download PDF

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Publication number
ES2636976T3
ES2636976T3 ES09717602T ES09717602T ES2636976T3 ES 2636976 T3 ES2636976 T3 ES 2636976T3 ES 09717602 T ES09717602 T ES 09717602T ES 09717602 T ES09717602 T ES 09717602T ES 2636976 T3 ES2636976 T3 ES 2636976T3
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Spain
Prior art keywords
antibody
antigen
malariae
ovale
complexes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES09717602T
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English (en)
Inventor
Larry G. Birkenmeyer
Anthony S. Muerhoff
Suresh M. Desai
George J. Dawson
Bruce J. Dille
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Abbott Laboratories
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Abbott Laboratories
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Filing date
Publication date
Priority claimed from US12/143,137 external-priority patent/US8030471B2/en
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of ES2636976T3 publication Critical patent/ES2636976T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/445—Plasmodium
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56905—Protozoa
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/44—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from protozoa
    • G01N2333/445—Plasmodium
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Un método para detectar anticuerpos contra P. malariae, P. ovale, P. vivax y P. falciparum en una muestra de ensayo que se sospecha que contiene al menos uno de dichos anticuerpos que comprende las etapas de: (a) poner en contacto dicha muestra de ensayo con 1) un antígeno de polipéptido MSP1-p19 de P. malariae que consiste en la secuencia de aminoácidos de SEQ ID NO: 47, 2) un antígeno de oolipéptido MSP1-p19 de P. ovale que consiste en la secuencia de aminoácidos de SEQ ID NO: 48, 3) un antígeno de polipéptido MSP1-p19 de P. vivax que consiste en la secuencia de aminoácidos de la SEQ ID NO: 45 y 4) un antígeno de polipéptido MSP1-p19 de P. falciparum que consiste en la secuencia de aminoácidos de SEQ ID NO: 46, en donde que los antígenos están unidos a una fase sólida, durante un tiempo y bajo condiciones suficientes para permitir la formación de complejos de anticuerpo/antígeno de P. malariae, complejos de anticuerpo/antígeno de P. ovale, complejos de anticuerpo/antígeno de P. vivax y complejos de anticuerpo/antígeno de P. falciparum; (b) añadir un producto conjugado a los complejos de anticuerpo/antígeno resultantes durante un tiempo y bajo condiciones suficientes para permitir que cada producto conjugado se una al anticuerpo unido, en donde dicho producto conjugado comprende un anti-anticuerpo humano anclado a un compuesto generador de señal capaz de generar un complejo detectable señal; y (c) detectar la presencia de anticuerpo contra el anticuerpo de P. malariae, P. ovale, P. vivax y P. falciparum que puede estar presente en dicha muestra de ensayo detectando la presencia de dicha señal generada por dicho compuesto generador de señal.
ES09717602T 2008-03-06 2009-03-05 Genes de Plasmodium malariae y Plasmodium ovale y usos de los mismos Active ES2636976T3 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US6837508P 2008-03-06 2008-03-06
US12/143,137 US8030471B2 (en) 2008-03-06 2008-06-20 Plasmodium malariae and Plasmodium ovale genes and uses thereof
US12/397,558 US8268981B2 (en) 2008-03-06 2009-03-04 Plasmodium malariae and plasmodium ovale genes and uses thereof
PCT/US2009/036098 WO2009111599A2 (en) 2008-03-06 2009-03-05 Plasmodium malariae and plasmodium ovale genes and uses thereof

Publications (1)

Publication Number Publication Date
ES2636976T3 true ES2636976T3 (es) 2017-10-10

Family

ID=41056643

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09717602T Active ES2636976T3 (es) 2008-03-06 2009-03-05 Genes de Plasmodium malariae y Plasmodium ovale y usos de los mismos

Country Status (4)

Country Link
US (1) US8268981B2 (es)
EP (1) EP2393824B1 (es)
ES (1) ES2636976T3 (es)
WO (1) WO2009111599A2 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8030471B2 (en) * 2008-03-06 2011-10-04 Abbott Laboratories Plasmodium malariae and Plasmodium ovale genes and uses thereof
EP3667322A1 (en) 2018-12-14 2020-06-17 Euroimmun Medizinische Labordiagnostika AG Serological detection of plasmodium antibodies
BR102020000922A2 (pt) * 2019-01-24 2021-11-30 Euroimmun Medizinische Labordiagnostika Ag Detecção sorológica de anticorpos de plasmodium

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WO1982001011A1 (en) 1980-09-24 1982-04-01 Corp Cetus Diagnostic method and probe
DE3381518D1 (de) 1982-01-22 1990-06-07 Cetus Corp Verfahren zur charakterisierung von hla und die darin benutzten cdns-testmittel.
US4582788A (en) 1982-01-22 1986-04-15 Cetus Corporation HLA typing method and cDNA probes used therein
US4683194A (en) 1984-05-29 1987-07-28 Cetus Corporation Method for detection of polymorphic restriction sites and nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
CA1284931C (en) 1986-03-13 1991-06-18 Henry A. Erlich Process for detecting specific nucleotide variations and genetic polymorphisms present in nucleic acids
US5107065A (en) 1986-03-28 1992-04-21 Calgene, Inc. Anti-sense regulation of gene expression in plant cells
CA1338457C (en) 1986-08-22 1996-07-16 Henry A. Erlich Purified thermostable enzyme
US5006309A (en) 1988-04-22 1991-04-09 Abbott Laboratories Immunoassay device with liquid transfer between wells by washing
US5089424A (en) 1988-06-14 1992-02-18 Abbott Laboratories Method and apparatus for heterogeneous chemiluminescence assay
US5063081A (en) 1988-11-14 1991-11-05 I-Stat Corporation Method of manufacturing a plurality of uniform microfabricated sensing devices having an immobilized ligand receptor
US5231020A (en) 1989-03-30 1993-07-27 Dna Plant Technology Corporation Genetic engineering of novel plant phenotypes
US5912120A (en) 1992-04-09 1999-06-15 The United States Of America As Represented By The Department Of Health And Human Services, Cloning, expression and diagnosis of human cytochrome P450 2C19: the principal determinant of s-mephenytoin metabolism
WO1995024488A1 (en) 1994-03-09 1995-09-14 Abbott Laboratories Transgenic animals producing oligosaccharides and glycoconjugates
US5750176A (en) 1994-03-09 1998-05-12 Abbott Laboratories Transgenic non-human mammal milk comprising 2'-fucosyl-lactose
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AU1600401A (en) 1999-11-12 2001-06-06 Chinese University Of Hong Kong, The Malaria vaccine
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Also Published As

Publication number Publication date
US8268981B2 (en) 2012-09-18
EP2393824B1 (en) 2017-05-31
WO2009111599A2 (en) 2009-09-11
US20090232797A1 (en) 2009-09-17
WO2009111599A3 (en) 2012-02-02
EP2393824A2 (en) 2011-12-14

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