ES2626410T3 - Composiciones de radiotrazadores peptídicos - Google Patents

Composiciones de radiotrazadores peptídicos Download PDF

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Publication number
ES2626410T3
ES2626410T3 ES11744007.3T ES11744007T ES2626410T3 ES 2626410 T3 ES2626410 T3 ES 2626410T3 ES 11744007 T ES11744007 T ES 11744007T ES 2626410 T3 ES2626410 T3 ES 2626410T3
Authority
ES
Spain
Prior art keywords
peptide
cmbp
met
compound
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES11744007.3T
Other languages
English (en)
Spanish (es)
Inventor
Peter Brian Iveson
Rajiv Bhalla
Bard Indrevoll
Gareth Getvoldsen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare Ltd
Original Assignee
GE Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GE Healthcare Ltd filed Critical GE Healthcare Ltd
Application granted granted Critical
Publication of ES2626410T3 publication Critical patent/ES2626410T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1833—Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nuclear Medicine (AREA)
ES11744007.3T 2010-08-18 2011-08-11 Composiciones de radiotrazadores peptídicos Active ES2626410T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1013808.9A GB201013808D0 (en) 2010-08-18 2010-08-18 Peptide radiotracer compositions
GB201013808 2010-08-18
PCT/EP2011/063890 WO2012022676A1 (en) 2010-08-18 2011-08-11 Peptide radiotracer compositions

Publications (1)

Publication Number Publication Date
ES2626410T3 true ES2626410T3 (es) 2017-07-25

Family

ID=42938098

Family Applications (1)

Application Number Title Priority Date Filing Date
ES11744007.3T Active ES2626410T3 (es) 2010-08-18 2011-08-11 Composiciones de radiotrazadores peptídicos

Country Status (19)

Country Link
US (1) US9533059B2 (https=)
EP (1) EP2605802B1 (https=)
JP (1) JP6014592B2 (https=)
KR (1) KR101853993B1 (https=)
CN (1) CN103153350B (https=)
AU (1) AU2011290856B2 (https=)
BR (1) BR112013003469A2 (https=)
CA (1) CA2807491C (https=)
CL (1) CL2013000483A1 (https=)
ES (1) ES2626410T3 (https=)
GB (1) GB201013808D0 (https=)
IL (1) IL224463A (https=)
MX (1) MX348733B (https=)
MY (1) MY163136A (https=)
NZ (1) NZ606466A (https=)
PH (1) PH12013500270A1 (https=)
RU (1) RU2594167C2 (https=)
SG (1) SG187878A1 (https=)
WO (1) WO2012022676A1 (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201103696D0 (en) 2011-03-04 2011-04-20 Ge Healthcare Ltd Technetium labelled peptides
GB201121914D0 (en) 2011-12-20 2012-02-01 Ge Healthcare Ltd Method for patient selection
GB201209082D0 (en) * 2012-05-24 2012-07-04 Ge Healthcare Ltd Purification method
GB201221266D0 (en) * 2012-11-27 2013-01-09 Ge Healthcare Ltd Aldehyde compositions
GB201314936D0 (en) 2013-08-21 2013-10-02 Ge Healthcare Ltd Radiolabelling method
GB201322451D0 (en) * 2013-12-18 2014-02-05 Ge Healthcare Ltd Purification method and compositions
GB201322456D0 (en) * 2013-12-18 2014-02-05 Ge Healthcare Ltd Radiotracer compositions and methods
US20190151483A1 (en) * 2016-07-25 2019-05-23 The United States Of America, As Represented By The Secretary, Department Of Health And Human Serv Methods of making 18f-labeled precursors and peptides, labeled c-met binding peptides, and methods of use thereof
GB201804835D0 (en) * 2018-03-26 2018-05-09 Ge Healthcare As Formulation and method of preparation
GB2589398B (en) * 2019-06-14 2023-02-15 Edinburgh Molecular Imaging Ltd Compounds and methods of use
GB201915206D0 (en) 2019-10-21 2019-12-04 Ge Healthcare Ltd Use of cyclodextrins as a radiostabilizer
SE2050387A1 (en) * 2020-04-06 2021-10-07 Pvac Medical Tech Ltd Labelled substance and methods of detection of inflammation and infection using said substance
TW202509086A (zh) * 2021-03-22 2025-03-01 日商肽夢想股份有限公司 c－Met蛋白質結合肽複合物
GB202105950D0 (en) * 2021-04-26 2021-06-09 Ge Healthcare Ltd Analytical HPLC

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5961955A (en) * 1997-06-03 1999-10-05 Coulter Pharmaceutical, Inc. Radioprotectant for peptides labeled with radioisotope
AU2002357388A1 (en) 2001-12-27 2003-07-24 The United States Of America, As Represented By The Department Of Veterans Affairs Monoclonal antibody imaging and therapy of tumors that express met and bind hepatocyte growth factor
PT2949658T (pt) * 2003-03-03 2018-10-18 Bracco Suisse Sa Péptidos que ligam especificamente o recetor de hgf (cmet) e utilizações dos mesmos
GB0305704D0 (en) * 2003-03-13 2003-04-16 Amersham Plc Radiofluorination methods
GB0420344D0 (en) * 2004-09-14 2004-10-13 Amersham Plc Diagnostic compounds
EP2043672A4 (en) * 2006-07-07 2009-10-21 Univ Leland Stanford Junior SELECTIVE INHIBITORS OF CASPASES
GB0615211D0 (en) 2006-07-31 2006-09-06 Ge Healthcare Uk Ltd Asymmetric flouro-substituted polymethine dyes
JP5603074B2 (ja) 2006-09-08 2014-10-08 ピラマル イメージング ソシエテ アノニム １８ｆ標識物質のための化合物と方法
EP2099499A2 (en) 2006-12-13 2009-09-16 GE Healthcare AS Synthesis of a radiofluorinated peptide using microwave activation technology
EP2114464A2 (en) * 2006-12-28 2009-11-11 GE Healthcare AS Radiofluorination methods
MX2009009291A (es) 2007-03-01 2009-12-14 Bayer Schering Pharma Ag Compuestos activos biologicamente marcados con fluoro-benzoilo 18f como agentes de diagnostico por imagenes asi como precursores de benzotriazol-1-iloxi-benzoilo, 2,5-dioxo-pirrolidin-1-iloxi benzoilo y trimetilamonio benzoilo.
KR101578225B1 (ko) 2007-05-16 2015-12-17 지이 헬스케어 에이에스 영상화를 위한 표지된 ｈｇｆ 결합성 펩티드
GB0718957D0 (en) * 2007-09-28 2007-11-07 Ge Healthcare Ltd Optical imaging agents
GB0718967D0 (en) * 2007-09-28 2007-11-07 Ge Healthcare Ltd Peptide imaging agents
GB0716897D0 (en) 2007-08-30 2007-10-10 Univ Muenchen Tech Cancer imaging and treatment
GB0803477D0 (en) 2008-02-26 2008-04-02 Ge Healthcare As Therapy selection method

Also Published As

Publication number Publication date
CA2807491A1 (en) 2012-02-23
EP2605802B1 (en) 2017-04-26
IL224463A (en) 2016-05-31
US20130149241A1 (en) 2013-06-13
PH12013500270A1 (en) 2013-04-01
US9533059B2 (en) 2017-01-03
KR20130135242A (ko) 2013-12-10
CA2807491C (en) 2019-06-04
CL2013000483A1 (es) 2014-03-07
JP6014592B2 (ja) 2016-10-25
BR112013003469A2 (pt) 2016-06-21
CN103153350A (zh) 2013-06-12
SG187878A1 (en) 2013-03-28
MY163136A (en) 2017-08-15
AU2011290856B2 (en) 2014-12-04
RU2013105491A (ru) 2014-09-27
EP2605802A1 (en) 2013-06-26
WO2012022676A1 (en) 2012-02-23
CN103153350B (zh) 2016-06-29
GB201013808D0 (en) 2010-09-29
AU2011290856A1 (en) 2013-03-14
KR101853993B1 (ko) 2018-05-02
RU2594167C2 (ru) 2016-08-10
MX348733B (es) 2017-06-27
JP2013540702A (ja) 2013-11-07
NZ606466A (en) 2014-11-28
MX2013001939A (es) 2013-03-18

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