ES2625829T3 - Conjugados y sus usos en la obtención de imágenes moleculares - Google Patents
Conjugados y sus usos en la obtención de imágenes moleculares Download PDFInfo
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- ES2625829T3 ES2625829T3 ES11788554.1T ES11788554T ES2625829T3 ES 2625829 T3 ES2625829 T3 ES 2625829T3 ES 11788554 T ES11788554 T ES 11788554T ES 2625829 T3 ES2625829 T3 ES 2625829T3
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- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0455—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1027—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against receptors, cell-surface antigens or cell-surface determinants
- A61K51/1033—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against receptors, cell-surface antigens or cell-surface determinants against receptors for cytokines, lymphokines or interferons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pyridine Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB201019118A GB201019118D0 (en) | 2010-11-11 | 2010-11-11 | Conjugates and their uses in molecular imaging |
| GB201019118 | 2010-11-11 | ||
| PCT/GB2011/001599 WO2012063028A1 (en) | 2010-11-11 | 2011-11-11 | Conjugates and their uses in molecular imaging |
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| ES2625829T3 true ES2625829T3 (es) | 2017-07-20 |
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| EP (1) | EP2637705B1 (enExample) |
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| ES (1) | ES2625829T3 (enExample) |
| GB (1) | GB201019118D0 (enExample) |
| WO (1) | WO2012063028A1 (enExample) |
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| US7098442B2 (en) | 2003-03-05 | 2006-08-29 | Raytheon Company | Thin micropolarizing filter, and a method for making it |
| CA2830349C (en) | 2011-03-17 | 2019-07-16 | The University Of Birmingham | Re-directed immunotherapy |
| EP4147724A1 (en) | 2013-10-31 | 2023-03-15 | Beth Israel Deaconess Medical Center | Near-infrared fluorescent contrast bioimaging agents and methods of use thereof |
| US11001562B2 (en) | 2013-10-31 | 2021-05-11 | Beth Israel Deaconess Medical Center | Near-infrared fluorescent nerve contrast agents and methods of use thereof |
| GB201417067D0 (en) | 2014-09-26 | 2014-11-12 | South African Nuclear Energy | Radiopharmaceutical conjugate |
| GB201504064D0 (en) * | 2015-03-10 | 2015-04-22 | Accretion Biotechnology Ltd | Method and kits for preparing radionuclide complexes |
| JP7253762B2 (ja) * | 2017-12-27 | 2023-04-07 | 慈濟大學 | タンパク質を表面に発現させた小胞によるオートファジー細胞およびアポトーシス細胞への薬剤送達 |
| US20250082795A1 (en) | 2023-09-12 | 2025-03-13 | Curadel Surgical Innovations, Inc. | Combinations of imaging agent conjugates and application thereof |
| CN120590625A (zh) * | 2024-11-06 | 2025-09-05 | 江苏申命医疗科技有限公司 | 一种放射性核素标记的聚合物、其制备方法及应用 |
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| GB8308235D0 (en) | 1983-03-25 | 1983-05-05 | Celltech Ltd | Polypeptides |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| JPS61134325A (ja) | 1984-12-04 | 1986-06-21 | Teijin Ltd | ハイブリツド抗体遺伝子の発現方法 |
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| EP0672142B1 (en) | 1992-12-04 | 2001-02-28 | Medical Research Council | Multivalent and multispecific binding proteins, their manufacture and use |
| AU2865995A (en) | 1995-06-14 | 1997-01-15 | Regents Of The University Of California, The | 3-hydroxy-2(1h)-pyridinone chelating agents |
| WO2007042504A2 (fr) * | 2005-10-07 | 2007-04-19 | Guerbet | Composes comprenant une partie de reconnaissance d'une cible biologique, couplee a une partie de signal capable de complexer le gallium |
| US8158804B2 (en) | 2007-01-11 | 2012-04-17 | Ge Healthcare As | Chelating agents |
| US8475768B2 (en) | 2007-08-13 | 2013-07-02 | Ge Healthcare As | Paramagnetic chelates thereof and their use as contrast agents in magnetic resonance imaging (MRI) |
| US9209965B2 (en) | 2014-01-14 | 2015-12-08 | Microsemi Semiconductor Ulc | Network interface with clock recovery module on line card |
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Also Published As
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| WO2012063028A1 (en) | 2012-05-18 |
| GB201019118D0 (en) | 2010-12-29 |
| JP5986095B2 (ja) | 2016-09-06 |
| AU2011327931A1 (en) | 2013-07-04 |
| US9138495B2 (en) | 2015-09-22 |
| AU2011327931A2 (en) | 2013-07-11 |
| US20140056810A1 (en) | 2014-02-27 |
| EP2637705B1 (en) | 2017-03-29 |
| AU2011327931B2 (en) | 2017-02-23 |
| EP2637705A1 (en) | 2013-09-18 |
| JP2014501714A (ja) | 2014-01-23 |
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