ES2625294T3 - Suplemento alimenticio biológicamente activo - Google Patents

Suplemento alimenticio biológicamente activo Download PDF

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ES2625294T3
ES2625294T3 ES10751072.9T ES10751072T ES2625294T3 ES 2625294 T3 ES2625294 T3 ES 2625294T3 ES 10751072 T ES10751072 T ES 10751072T ES 2625294 T3 ES2625294 T3 ES 2625294T3
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vitamin
leuzea
ascorbic acid
food supplement
excipients
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Dmitriy Gennadjevich Elistratov
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Parafarm OOO
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/16—Inorganic salts, minerals or trace elements
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00—Shaping or working of foodstuffs characterised by the products
    • A23P10/20—Agglomerating; Granulating; Tabletting
    • A23P10/28—Tabletting; Making food bars by compression of a dry powdered mixture
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A61K35/64—Insects, e.g. bees, wasps or fleas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/06—Anabolic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

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Abstract

Suplemento alimenticio que contiene leuzea, ácido ascórbico (Vitamina C) y Vitamina E y excipientes (estearato de calcio, talco, lactosa), que difiere en que contiene cría de abeja macho con la siguiente proporción de componentes (% en masa): Cría de abeja macho 1-70; Leuzea 5-70; Ácido ascórbico 1-70; Vitamina E 0,05 - 30; Excipientes- el resto.

Description

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SUPLEMENTO ALIMENTICIO BIOLOGICAMENTE ACTIVO
Description
Esta invention se refiere a la industria alimentaria, en particular, a complementos alimenticios, destinados a aumentar la masa muscular de los atletas.
Los mejores bioestimulantes y productos ricos en energia comprenden los preparados desarrollados sobre la base de productos apicolas. Existe un preparado conocido "Tonus" TU-6402-06-244-91 desarrollado a base de polen de flores y lactosa, y aprobado por el Jefe del Departamento Sanitario del Presidente de la Federation Rusa, que es producido por BIOCOR. Sin embargo, este preparado no contiene un complejo multivitammico y microelementos vitales. Su efecto en el cuerpo humano esta gobernado unicamente por el polen de las flores, lo que puede obstaculizar la comprension de la actividad biologica de "Tonus", ya que es necesario saber con precision cuando se recoge el polen y de que plantas.
El documento RU 2 233 666 C1 muestra una composition que se utiliza como composition anabolica. La composicion comprende cria de abeja macho como agente activo.
El documento DE 196 27 627 A1 describe una composicion que comprende un extracto de cria de abeja macho. La composicion puede usarse topicamente para el tratamiento de enfermedades musculares.
Lo mas proximo a la invencion por la sustancia tecnica y el resultado conseguido es el complejo multivitammico natural "Leveton", Patente RU 2066963 C1 (IPC A23L001 / 076). Contiene el polen de las flores (carga de polen), leuzea, acido ascorbico, acetato de a-tocoferol, propoleo, estearato de calcio, talco y lactosa con la siguiente relation de componentes (% en masa): polen de flores (carga de polen) 50-51, leuzea 10, acido ascorbico 3,0-3,5, acetato de a-tocoferol 0,15, propoleo 2, estearato de calcio 0,92-0,95, talco 3, lactosa - el resto. "Leveton" se desarrolla para aumentar las propiedades de resistencia de los atletas y la masa muscular, y ha sido utilizado activamente por las escuelas de mayor deportividad durante mas de 10 anos. El efecto "Leveton" esta condicionado por la sinergia de sus componentes: concretamente vitaminas dosificadas y donantes de fitoecdisteroides, a saber, leuzea y polen de la flor (carga del polen).
En la invencion propuesta, se sugiere que el polen de las flores (carga de polen) sea sustituido por cria de abeja macho, una sustancia que posee un efecto anabolico mas fuerte que el polen de las flores, sirve como un farmaco natural que permite aumentar la masa muscular, protege los musculos de danos bioquimicos y logra los maximos resultados.
La cria de abeja macho difiere del polen de las flores por un mayor numero de grupos funcionales de enzimas de sulfuro, asi como hormonas, a saber, testosterona, progesterona y estradiol. Gracias
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a este conjunto de sustancias, la cria de abeja macho promueve una mayor restauracion de las caracteristicas bioqmmicas y de masa metrica de la glandula mamaria y la glandula prostatica, siendo un estimulante de los mecanismos centrales reguladores de la intensidad de la formation de androgenos.
Composition qmmica: proteinas 10-20%; carbohidratos 1-5,5%; grasas 5-6,3%; aminoacidos 11,4%; glucosa 3,18-5%; fructosa y sacarosa hasta 0,5%.
Microelementos (% mg): K 0,50, Na 38, Ca 14, P 189, Mg 2, Fe 3,23, Mn 4,40%, Zn 5,54, Cu 2,
Cr, Co, Ni, Ag, Au y otros.
Vitaminas (agua y liposolubles): A 0,54 UI / g; xantofila 0,297 mg%; B - carotina 0,426 UI / g;
B2 0,739 mg%; D 950 UI / g; colina 442,8 mg%; acido nicotmico 15,8 mg%.
La cria de abeja macho aumenta el nivel del metabolismo durante el periodo de actividad muscular activa debido a que aumenta la resistencia fisica. La cria de abeja macho contiene 10 veces mas hormonas esteroides en comparacion con el polen de las flores.
A dia de hoy, "Leveton" no cumple con los requisitos actuales para el rapido crecimiento de la masa muscular de los atletas, no asegura la recuperation rapida de los musculos fatigados despues de una carga fisica dura. La invention propuesta hace que el proceso de recuperation de un atleta sea mas corto en comparacion con un prototipo a expensas de un mayor contenido de fitoecdisteroides.
El resultado tecnico anterior se consigue debido a que la cria de abeja macho se introduce adicionalmente en el conocido producto terapeutico-profilactico "Leveton" que contiene leuzea, acido ascorbico (Vitamina C) y Vitamina E y excipientes, y la carga de polen se elimina de su composicion con la siguiente proportion de componentes (% en masa):
Cria de abeja macho 1-70;
Leuzea 5-70;
Acido ascorbico 1-70;
Vitamina E 0,05 - 30;
Excipientes- el resto
Como excipientes, se puede usar, por ejemplo, estearato de calcio 0,92-0,95, talco 3-6, lactosa - el resto.
En el proceso de busqueda por fuentes de information cientifico-tecnica y de patentes, no se encontro ninguna sustancia que posea un agregado similar de caracteristicas esenciales con el mismo efecto positivo conseguido. As^ la invention propuesta presenta una solution tecnica de la tarea, posee novedad, nivel inventivo y utilidad industrial. El producto terapeutico-profilactico se fabrica en forma de comprimido. Se determina un nivel inferior por conveniencia de uso del
complejo propuesto, es dedr, el uso de un numero menor de comprimidos. Se determina un nivel superior por el hecho de que, en caso de un mayor porcentaje de proportion, sera dificil fabricar un comprimido, ya que se descompondra.
Ejemplo 1
5 Un ejemplo de la formulation de mezcla para una tableta de masa 500 g:

Cria de abeja macho 10 mg Leuzea 50 mg

Acido ascorbico 50 mg

Vitamina E 5 mg
10 Excipientes 385 mg
Por lo tanto, el suplemento alimenticio propuesto desarrollado sobre la base de extractos de leuzea, cria de abeja macho, acido ascorbico (Vitamina C), Vitamina E, puede utilizarse como un producto para el crecimiento de la masa muscular de los atletas debido a un mayor contenido de 15 fitoecdisteroides, fitohormonas que influyen en el proceso anabolico en el cuerpo de un atleta.
El producto no solo produce un efecto anabolico en el cuerpo humano, sino que se recomienda para la profilaxis de disfunciones del sistema nervioso central, el tratamiento de enfermedades de la glandula prostatica y tambien la perdida de poder sexual.

Claims (1)

  1. Reivindicaciones
    1. Suplemento alimenticio que contiene leuzea, acido ascorbico (Vitamina C) y Vitamina E y excipientes (estearato de calcio, talco, lactosa), que difiere en que contiene cria de abeja macho con la siguiente proportion de componentes (% en masa):
    5 Cria de abeja macho 1-70;
    Leuzea 5-70;
    Acido ascorbico 1-70;
    Vitamina E 0,05 - 30;
    Excipientes- el resto.
ES10751072.9T 2009-03-13 2010-03-03 Suplemento alimenticio biológicamente activo Active ES2625294T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
RU2009109273/13A RU2390270C1 (ru) 2009-03-13 2009-03-13 Биологически активная добавка к пище
RU2009109273 2009-03-13
PCT/RU2010/000098 WO2010104418A1 (ru) 2009-03-13 2010-03-03 Биологически активная добавка к пище

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ES2625294T3 true ES2625294T3 (es) 2017-07-19

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US (3) US20120003200A1 (es)
EP (1) EP2407035B1 (es)
CN (1) CN102791149B (es)
CA (1) CA2793071C (es)
DK (1) DK2407035T3 (es)
EA (1) EA019184B1 (es)
ES (1) ES2625294T3 (es)
LT (1) LT2407035T (es)
PL (1) PL2407035T3 (es)
RU (1) RU2390270C1 (es)
UA (1) UA108465C2 (es)
WO (1) WO2010104418A1 (es)

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RU2414229C1 (ru) * 2009-10-12 2011-03-20 Общество С Ограниченной Ответственностью "Парафарм" Лекарственное средство для профилактики и лечения аденомы и простатита
RU2425593C1 (ru) * 2010-05-04 2011-08-10 Общество С Ограниченной Ответственностью "Парафарм" Биологически активная добавка к пище для нормализации уровня андрогенов мужчин, общего состояния, снижения ожирения
RU2458537C1 (ru) * 2011-03-14 2012-08-20 Общество С Ограниченной Ответственностью "Парафарм" Биологически активная добавка к пище для профилактики эректильной дисфункции у мужчин
RU2456005C1 (ru) * 2011-04-20 2012-07-20 Общество с ограниченной ответственностью фирма "Биокор" Способ приготовления биологически активного препарата
RU2509569C2 (ru) * 2011-07-05 2014-03-20 Общество С Ограниченной Ответственностью "Парафарм" Композиция для лечения и предупреждения остеоартрита и остеоартроза суставов
RU2493733C2 (ru) * 2011-07-05 2013-09-27 Общество С Ограниченной Ответственностью "Парафарм" Тонизирующий напиток
RU2491078C2 (ru) * 2011-09-16 2013-08-27 Общество С Ограниченной Ответственностью "Парафарм" Способ приготовления расплода трутневого адсорбированного и его состав
RU2561863C1 (ru) * 2014-03-12 2015-09-10 Автономная некоммерческая организация содействия социально-экономическому развитию "ИНЖЭКОН-Тверь" Способ изготовления биологического стимулятора
US9700589B2 (en) * 2015-02-03 2017-07-11 Naturex Sa Compositions and methods for improved muscle metabolism
RU2577225C1 (ru) * 2015-03-27 2016-03-10 Общество С Ограниченной Ответственностью "Парафарм" Препарат и способ для лечения дефицита андрогенов у женщин, содержащий энтомологические протеины
FR3078252B1 (fr) * 2018-02-28 2020-08-14 Biophytis Phytoecdysones pour leur utilisation dans la prevention de la perte de force musculaire lors d’une immobilisation
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CN102791149A (zh) 2012-11-21
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US20120003200A1 (en) 2012-01-05
EP2407035A1 (en) 2012-01-18
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PL2407035T3 (pl) 2017-07-31
US20140314870A1 (en) 2014-10-23
RU2390270C1 (ru) 2010-05-27
CA2793071A1 (en) 2010-09-16
EP2407035B1 (en) 2017-02-22
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