ES2603381T3 - Derivados de prostaglandinas para tratar el estreñimiento - Google Patents
Derivados de prostaglandinas para tratar el estreñimiento Download PDFInfo
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- ES2603381T3 ES2603381T3 ES05782157.1T ES05782157T ES2603381T3 ES 2603381 T3 ES2603381 T3 ES 2603381T3 ES 05782157 T ES05782157 T ES 05782157T ES 2603381 T3 ES2603381 T3 ES 2603381T3
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- 238000012986 modification Methods 0.000 description 1
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- 230000003387 muscular Effects 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 208000018360 neuromuscular disease Diseases 0.000 description 1
- 239000012457 nonaqueous media Substances 0.000 description 1
- 229960002446 octanoic acid Drugs 0.000 description 1
- 235000008390 olive oil Nutrition 0.000 description 1
- 239000004006 olive oil Substances 0.000 description 1
- 229940127240 opiate Drugs 0.000 description 1
- 239000000014 opioid analgesic Substances 0.000 description 1
- 229940005483 opioid analgesics Drugs 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 239000002357 osmotic agent Substances 0.000 description 1
- 239000008188 pellet Substances 0.000 description 1
- 208000011906 peptic ulcer disease Diseases 0.000 description 1
- 230000004962 physiological condition Effects 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 229940050929 polyethylene glycol 3350 Drugs 0.000 description 1
- 229920000151 polyglycol Polymers 0.000 description 1
- 239000010695 polyglycol Substances 0.000 description 1
- 229950008882 polysorbate Drugs 0.000 description 1
- 229920000136 polysorbate Polymers 0.000 description 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
- 150000003165 prostaglandin E1 derivatives Chemical class 0.000 description 1
- XEYBRNLFEZDVAW-UHFFFAOYSA-N prostaglandin E2 Natural products CCCCCC(O)C=CC1C(O)CC(=O)C1CC=CCCCC(O)=O XEYBRNLFEZDVAW-UHFFFAOYSA-N 0.000 description 1
- 230000002040 relaxant effect Effects 0.000 description 1
- 238000007363 ring formation reaction Methods 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 150000004671 saturated fatty acids Chemical class 0.000 description 1
- 230000016160 smooth muscle contraction Effects 0.000 description 1
- 239000007901 soft capsule Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 230000001148 spastic effect Effects 0.000 description 1
- 208000010110 spontaneous platelet aggregation Diseases 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 230000036262 stenosis Effects 0.000 description 1
- 239000008174 sterile solution Substances 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 125000005472 straight-chain saturated fatty acid group Chemical group 0.000 description 1
- 125000001424 substituent group Chemical group 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 239000011593 sulfur Substances 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 230000002459 sustained effect Effects 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- FKHIFSZMMVMEQY-UHFFFAOYSA-N talc Chemical compound [Mg+2].[O-][Si]([O-])=O FKHIFSZMMVMEQY-UHFFFAOYSA-N 0.000 description 1
- 229960004354 tegaserod maleate Drugs 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000032258 transport Effects 0.000 description 1
- ODLHGICHYURWBS-LKONHMLTSA-N trappsol cyclo Chemical compound CC(O)COC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](COCC(C)O)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](COCC(C)O)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](COCC(C)O)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](COCC(C)O)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)COCC(O)C)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1COCC(C)O ODLHGICHYURWBS-LKONHMLTSA-N 0.000 description 1
- DSDAICPXUXPBCC-MWDJDSKUSA-N trimethyl-β-cyclodextrin Chemical compound COC[C@H]([C@H]([C@@H]([C@H]1OC)OC)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](COC)[C@H]([C@@H]([C@H]3OC)OC)O[C@H]3O[C@H](COC)[C@H]([C@@H]([C@H]3OC)OC)O[C@H]3O[C@H](COC)[C@H]([C@@H]([C@H]3OC)OC)O[C@H]3O[C@H](COC)[C@H]([C@@H]([C@H]3OC)OC)O3)[C@H](OC)[C@H]2OC)COC)O[C@@H]1O[C@H]1[C@H](OC)[C@@H](OC)[C@@H]3O[C@@H]1COC DSDAICPXUXPBCC-MWDJDSKUSA-N 0.000 description 1
- 150000004670 unsaturated fatty acids Chemical class 0.000 description 1
- 235000021122 unsaturated fatty acids Nutrition 0.000 description 1
- 230000024883 vasodilation Effects 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/558—Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US60652104P | 2004-09-02 | 2004-09-02 | |
| US606521P | 2004-09-02 | ||
| US66631705P | 2005-03-30 | 2005-03-30 | |
| US666317P | 2005-03-30 | ||
| US66659305P | 2005-03-31 | 2005-03-31 | |
| US666593P | 2005-03-31 | ||
| PCT/JP2005/016464 WO2006025599A1 (fr) | 2004-09-02 | 2005-09-01 | Dérivés de prostaglandine pour le traitement de troubles gastro-intestinaux |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2603381T3 true ES2603381T3 (es) | 2017-02-27 |
Family
ID=35229739
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES05782157.1T Active ES2603381T3 (es) | 2004-09-02 | 2005-09-01 | Derivados de prostaglandinas para tratar el estreñimiento |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US8748481B2 (fr) |
| EP (1) | EP1791545B1 (fr) |
| JP (4) | JP2008511541A (fr) |
| KR (4) | KR20170003712A (fr) |
| CN (1) | CN102885821A (fr) |
| AR (1) | AR050626A1 (fr) |
| AU (1) | AU2005278323B2 (fr) |
| BR (1) | BRPI0514891A (fr) |
| CA (1) | CA2577284A1 (fr) |
| ES (1) | ES2603381T3 (fr) |
| IL (1) | IL181332A (fr) |
| MX (1) | MX2007002602A (fr) |
| NO (1) | NO340989B1 (fr) |
| NZ (1) | NZ553434A (fr) |
| TW (1) | TWI387454B (fr) |
| WO (1) | WO2006025599A1 (fr) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2379652T3 (es) * | 2002-10-23 | 2012-04-30 | Sucampo Ag | Compuestos de prostaglandina para el tratamiento de obesidad |
| WO2005002588A1 (fr) * | 2003-07-03 | 2005-01-13 | Sucampo Ag | Composition entero-soluble comprenant des analogues de prostaglandine, utilisee comme agent d'ouverture des canaux a chlorure |
| NZ570190A (en) | 2006-01-24 | 2011-03-31 | Sucampo Ag | Pharmaceutical composition comprising a bi-cyclic compound and method for stabilizing the bi-cyclic compound |
| US20090030072A1 (en) * | 2007-07-03 | 2009-01-29 | Sucampo Ag | Pharmaceutical combination of opioid and prostaglandin compound |
| CN108685929A (zh) * | 2012-04-23 | 2018-10-23 | 苏坎波公司 | 用于治疗具有腹泻的肠易激综合征的方法 |
| US10022389B2 (en) * | 2013-02-04 | 2018-07-17 | Taisho Pharmaceutical Co., Ltd. | Prophylactic or therapeutic drug for constipation |
| WO2014159679A1 (fr) | 2013-03-12 | 2014-10-02 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Procédés pour utiliser la lubiprostone pour absorber un fluide depuis l'espace sous-rétinien |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5428062A (en) | 1987-01-28 | 1995-06-27 | K.K. Ueno Seiyaku Oyo Kenkyujo | Prostaglandins E and anti ulcers containing same |
| US5166174A (en) | 1987-01-28 | 1992-11-24 | K.K. Ueno Seiyaku Oyo Kenkyujo | Prostaglandins E and anti-ulcers containing same |
| US5225439A (en) | 1987-01-28 | 1993-07-06 | K.K. Ueno Seiyaku Oyo Kenkyujo | Prostaglandins E and anti ulcers containing same |
| US5317032A (en) * | 1987-10-02 | 1994-05-31 | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo | Prostaglandin cathartic |
| PT1220849E (pt) | 1999-10-15 | 2004-10-29 | Sucampo Ag | Composicao de compostos biciclicos e metodo para a sua estabilizacao |
| US6414016B1 (en) * | 2000-09-05 | 2002-07-02 | Sucampo, A.G. | Anti-constipation composition |
| TWI302100B (en) * | 2001-05-02 | 2008-10-21 | Sucampo Ag | Composition for treating drug-induced constipation |
| AR035242A1 (es) | 2001-05-18 | 2004-05-05 | Sucampo Ag | Uso de un lipido bioactivo halogenadopara preparar una composicion catartica y compuesto lipido bioactivo halogenado |
| AU2002330747B2 (en) * | 2001-08-31 | 2007-07-19 | Sucampo Ag | Prostaglandin analogs as chloride channel opener |
| TWI331920B (en) * | 2001-11-14 | 2010-10-21 | Sucampo Ag | Unit dosage form for relieving or treating constipation in human patients |
| TWI263505B (en) | 2001-11-19 | 2006-10-11 | Sucampo Ag | Pharmaceutical composition comprising a C1C-2 channel opener |
| CN1753680B (zh) * | 2002-12-27 | 2010-12-08 | 苏坎波公司 | 用于治疗腹部不适的前列腺素衍生物 |
| WO2005002588A1 (fr) | 2003-07-03 | 2005-01-13 | Sucampo Ag | Composition entero-soluble comprenant des analogues de prostaglandine, utilisee comme agent d'ouverture des canaux a chlorure |
-
2005
- 2005-08-31 TW TW094129818A patent/TWI387454B/zh active
- 2005-09-01 EP EP05782157.1A patent/EP1791545B1/fr not_active Not-in-force
- 2005-09-01 MX MX2007002602A patent/MX2007002602A/es active IP Right Grant
- 2005-09-01 KR KR1020167036382A patent/KR20170003712A/ko active Application Filing
- 2005-09-01 JP JP2007511111A patent/JP2008511541A/ja not_active Withdrawn
- 2005-09-01 KR KR1020187008381A patent/KR20180033310A/ko active Search and Examination
- 2005-09-01 CN CN2012103704021A patent/CN102885821A/zh active Pending
- 2005-09-01 US US11/216,012 patent/US8748481B2/en active Active
- 2005-09-01 BR BRPI0514891-0A patent/BRPI0514891A/pt not_active Application Discontinuation
- 2005-09-01 AU AU2005278323A patent/AU2005278323B2/en active Active
- 2005-09-01 KR KR1020137034994A patent/KR20140019006A/ko not_active Application Discontinuation
- 2005-09-01 KR KR1020077004900A patent/KR20070048221A/ko not_active Application Discontinuation
- 2005-09-01 NZ NZ553434A patent/NZ553434A/en unknown
- 2005-09-01 ES ES05782157.1T patent/ES2603381T3/es active Active
- 2005-09-01 WO PCT/JP2005/016464 patent/WO2006025599A1/fr active Application Filing
- 2005-09-01 CA CA002577284A patent/CA2577284A1/fr not_active Withdrawn
- 2005-09-02 AR ARP050103687A patent/AR050626A1/es not_active Application Discontinuation
-
2007
- 2007-02-14 IL IL181332A patent/IL181332A/en not_active IP Right Cessation
- 2007-03-30 NO NO20071704A patent/NO340989B1/no not_active IP Right Cessation
-
2012
- 2012-10-19 JP JP2012232180A patent/JP2013049688A/ja not_active Withdrawn
-
2014
- 2014-04-30 US US14/265,801 patent/US20140315994A1/en not_active Abandoned
-
2015
- 2015-05-19 JP JP2015102184A patent/JP6408426B2/ja active Active
-
2018
- 2018-05-29 JP JP2018102339A patent/JP2018150354A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| JP2018150354A (ja) | 2018-09-27 |
| NO340989B1 (no) | 2017-07-31 |
| IL181332A (en) | 2015-09-24 |
| TWI387454B (zh) | 2013-03-01 |
| AU2005278323B2 (en) | 2011-03-17 |
| JP6408426B2 (ja) | 2018-10-17 |
| US20140315994A1 (en) | 2014-10-23 |
| KR20180033310A (ko) | 2018-04-02 |
| AR050626A1 (es) | 2006-11-08 |
| KR20070048221A (ko) | 2007-05-08 |
| US20060063830A1 (en) | 2006-03-23 |
| AU2005278323A1 (en) | 2006-03-09 |
| KR20140019006A (ko) | 2014-02-13 |
| MX2007002602A (es) | 2007-04-25 |
| IL181332A0 (en) | 2007-07-04 |
| EP1791545B1 (fr) | 2016-08-31 |
| WO2006025599A1 (fr) | 2006-03-09 |
| BRPI0514891A (pt) | 2008-06-24 |
| JP2013049688A (ja) | 2013-03-14 |
| JP2015166377A (ja) | 2015-09-24 |
| KR20170003712A (ko) | 2017-01-09 |
| EP1791545A1 (fr) | 2007-06-06 |
| CN102885821A (zh) | 2013-01-23 |
| NO20071704L (no) | 2007-05-31 |
| TW200612901A (en) | 2006-05-01 |
| JP2008511541A (ja) | 2008-04-17 |
| NZ553434A (en) | 2010-01-29 |
| US8748481B2 (en) | 2014-06-10 |
| CA2577284A1 (fr) | 2006-03-09 |
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