ES259139A1 - Process for n-methylacridone - Google Patents
Process for n-methylacridoneInfo
- Publication number
- ES259139A1 ES259139A1 ES0259139A ES259139A ES259139A1 ES 259139 A1 ES259139 A1 ES 259139A1 ES 0259139 A ES0259139 A ES 0259139A ES 259139 A ES259139 A ES 259139A ES 259139 A1 ES259139 A1 ES 259139A1
- Authority
- ES
- Spain
- Prior art keywords
- water
- reaction mixture
- methylacridone
- methyl
- chloroacridine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B48/00—Quinacridones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
Abstract
N-Methylacridone is made by reacting a mole of N-phenylanthranilic acid with at least 2 moles of phosphorous oxychloride in a solvent for the reactants and intermediate having a boiling point of at least 120 DEG C., e.g. chlorobenzene, heating the reaction mixture at an initial temperature of 55-60 DEG C. until formation of acridone is substantially complete, thereafter increasing the temperature of the reaction mixture to 95-100 DEG C. until formation of 9-chloroacridine is substantially complete, quenching the reaction mixture in water, separating the solvent layer from the resulting water layer and adding thereto a methyl quaternizing agent, such as dimethyl sulphate, methyl iodide or methyl bromide, extracting the resulting quaternary salt of 9-chloroacridine with water and treating said water extraction with mineral acid, e.g. hydrochloric acid, to obtain N-methylacridone.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US82241759A | 1959-06-24 | 1959-06-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES259139A1 true ES259139A1 (en) | 1960-10-01 |
Family
ID=25235974
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0259139A Expired ES259139A1 (en) | 1959-06-24 | 1960-06-22 | Process for n-methylacridone |
Country Status (3)
| Country | Link |
|---|---|
| CH (1) | CH393328A (en) |
| ES (1) | ES259139A1 (en) |
| GB (1) | GB920737A (en) |
-
1960
- 1960-06-20 GB GB21599/60A patent/GB920737A/en not_active Expired
- 1960-06-22 ES ES0259139A patent/ES259139A1/en not_active Expired
- 1960-06-23 CH CH714060A patent/CH393328A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CH393328A (en) | 1965-06-15 |
| GB920737A (en) | 1963-03-13 |
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