ES2560557T3 - Materiales y métodos con relación a la glicosilación de polipéptidos terapéuticos - Google Patents
Materiales y métodos con relación a la glicosilación de polipéptidos terapéuticos Download PDFInfo
- Publication number
- ES2560557T3 ES2560557T3 ES10727485.4T ES10727485T ES2560557T3 ES 2560557 T3 ES2560557 T3 ES 2560557T3 ES 10727485 T ES10727485 T ES 10727485T ES 2560557 T3 ES2560557 T3 ES 2560557T3
- Authority
- ES
- Spain
- Prior art keywords
- group
- alkyl
- polypeptide
- glycosylation
- sugar
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/549—Sugars, nucleosides, nucleotides or nucleic acids
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18743409P | 2009-06-16 | 2009-06-16 | |
| US187434P | 2009-06-16 | ||
| PCT/GB2010/001188 WO2010146362A2 (en) | 2009-06-16 | 2010-06-16 | Materials and methods relating to glycosylation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2560557T3 true ES2560557T3 (es) | 2016-02-19 |
Family
ID=43086298
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES10727485.4T Active ES2560557T3 (es) | 2009-06-16 | 2010-06-16 | Materiales y métodos con relación a la glicosilación de polipéptidos terapéuticos |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US9452223B2 (https=) |
| EP (1) | EP2442831B9 (https=) |
| JP (2) | JP6091892B2 (https=) |
| CN (1) | CN102481377B (https=) |
| CA (1) | CA2768155C (https=) |
| ES (1) | ES2560557T3 (https=) |
| PL (1) | PL2442831T3 (https=) |
| WO (1) | WO2010146362A2 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2560557T3 (es) * | 2009-06-16 | 2016-02-19 | Glythera Limited | Materiales y métodos con relación a la glicosilación de polipéptidos terapéuticos |
| TW201442721A (zh) * | 2013-01-23 | 2014-11-16 | Daiichi Sankyo Co Ltd | 糖鏈修飾心房利尿鈉肽 |
| WO2015148915A1 (en) * | 2014-03-27 | 2015-10-01 | Academia Sinica | Reactive labelling compounds and uses thereof |
| RU2656140C2 (ru) * | 2016-11-14 | 2018-05-31 | Федеральное государственное бюджетное учреждение "Государственный научный центр Институт иммунологии" Федерального медико-биологического агентства России | Способ получения гибридного белка, состоящего из рекомбинантного белка аналога интерферона гамма, конъюгированного с олигосахаридом |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE193551T1 (de) * | 1991-03-18 | 2000-06-15 | Scripps Research Inst | Oligosaccharide als enzymsubstrate und - inhibitoren: verfahren und zusammensetzungen |
| US5770407A (en) | 1996-12-10 | 1998-06-23 | The Scripps Research Institute | Process for preparing nucleotide inhibitors of glycosyltransferases |
| EP2042196B1 (en) * | 2001-10-10 | 2016-07-13 | ratiopharm GmbH | Remodelling and glycoconjugation of Granulocyte Colony Stimulating Factor (G-CSF) |
| US7226903B2 (en) * | 2001-10-10 | 2007-06-05 | Neose Technologies, Inc. | Interferon beta: remodeling and glycoconjugation of interferon beta |
| MXPA05003978A (es) * | 2002-10-16 | 2005-06-22 | Scripps Research Inst | Sintesis de glicoproteinas. |
| KR20100016160A (ko) * | 2007-04-03 | 2010-02-12 | 바이오제너릭스 에이지 | 글리코페길화 ｇ―ｃｓｆ를 이용하는 치료 방법 |
| CA2704234A1 (en) * | 2007-11-09 | 2009-05-14 | Baxter International Inc. | Modified recombinant factor viii and von willebrand factor and methods of use |
| ES2560557T3 (es) * | 2009-06-16 | 2016-02-19 | Glythera Limited | Materiales y métodos con relación a la glicosilación de polipéptidos terapéuticos |
-
2010
- 2010-06-16 ES ES10727485.4T patent/ES2560557T3/es active Active
- 2010-06-16 CN CN201080031987.3A patent/CN102481377B/zh active Active
- 2010-06-16 US US13/378,192 patent/US9452223B2/en active Active
- 2010-06-16 PL PL10727485T patent/PL2442831T3/pl unknown
- 2010-06-16 WO PCT/GB2010/001188 patent/WO2010146362A2/en not_active Ceased
- 2010-06-16 CA CA2768155A patent/CA2768155C/en active Active
- 2010-06-16 EP EP10727485.4A patent/EP2442831B9/en active Active
- 2010-06-16 JP JP2012515554A patent/JP6091892B2/ja active Active
-
2015
- 2015-06-16 JP JP2015121185A patent/JP2015187153A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20120190631A1 (en) | 2012-07-26 |
| HK1169336A1 (zh) | 2013-02-22 |
| JP2012530119A (ja) | 2012-11-29 |
| CA2768155C (en) | 2016-08-23 |
| WO2010146362A2 (en) | 2010-12-23 |
| CA2768155A1 (en) | 2010-12-23 |
| PL2442831T3 (pl) | 2016-06-30 |
| CN102481377B (zh) | 2014-10-29 |
| EP2442831B9 (en) | 2016-05-11 |
| EP2442831B1 (en) | 2015-11-04 |
| CN102481377A (zh) | 2012-05-30 |
| JP2015187153A (ja) | 2015-10-29 |
| US9452223B2 (en) | 2016-09-27 |
| WO2010146362A3 (en) | 2011-06-30 |
| JP6091892B2 (ja) | 2017-03-08 |
| EP2442831A2 (en) | 2012-04-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2674099T3 (es) | Reactivos con funcionalidad tiol y sus usos | |
| ES2810755T3 (es) | Conjugados fármaco-anticuerpo anti-lrrc15 humano y métodos para su uso | |
| ES2560557T3 (es) | Materiales y métodos con relación a la glicosilación de polipéptidos terapéuticos | |
| JP2017538666A (ja) | スルファミドリンカー、スルファミドリンカーのコンジュゲート、及び調製の方法 | |
| TW200526237A (en) | Administration of TLR7 ligands and prodrugs thereof for treatment of infection by hepatitis C virus | |
| JP2022546557A (ja) | 治療的に活性な複合体のアシアロ糖タンパク質受容体媒介送達 | |
| ES2390930T3 (es) | Sal de ácido p-toluensulfónico de 5-amino-3-(2'-O-acetil-3'-desoxi-beta-D-ribofuranosil)-3H-tiazolo[4,5-d]pirimidin-2-ona y procedimientos e preparación | |
| CA3189715A1 (en) | Glycosylated il-2 proteins and uses thereof | |
| WO2008029278A2 (en) | Conjugates of antithrombin binding oligosaccharide derivatives and therapeutic proteins | |
| HK1169336B (en) | Materials and methods relating to glycosylation of a therapeutic polypeptide | |
| JP2012530119A5 (https=) | ||
| HK1210026B (en) | Thiol-functionalising reagents and their uses | |
| ES2357001T3 (es) | Conjugados de almidón hidroxialquilico y de g-csf. | |
| CN101087801A (zh) | 支化聚合物糖及其核苷酸 | |
| HK1165435B (en) | Thiol-functionalising reagents and their uses |