ES2557935T3 - Inmunomodulación mediante lectina de tipo C - Google Patents
Inmunomodulación mediante lectina de tipo C Download PDFInfo
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- ES2557935T3 ES2557935T3 ES08776024.5T ES08776024T ES2557935T3 ES 2557935 T3 ES2557935 T3 ES 2557935T3 ES 08776024 T ES08776024 T ES 08776024T ES 2557935 T3 ES2557935 T3 ES 2557935T3
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2851—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A61K2039/507—Comprising a combination of two or more separate antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6056—Antibodies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
- A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
- A61K2239/57—Skin; melanoma
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/74—Inducing cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/75—Agonist effect on antigen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
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- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- Chemical Kinetics & Catalysis (AREA)
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- Neurosurgery (AREA)
- Neurology (AREA)
- Transplantation (AREA)
- Gastroenterology & Hepatology (AREA)
- Communicable Diseases (AREA)
- Rheumatology (AREA)
Applications Claiming Priority (5)
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| US92999907P | 2007-07-20 | 2007-07-20 | |
| US929999P | 2007-07-20 | ||
| GB0805159 | 2008-03-19 | ||
| GBGB0805159.1A GB0805159D0 (en) | 2008-03-19 | 2008-03-19 | Immune modulation via C-type lectin |
| PCT/GB2008/002504 WO2009013484A1 (en) | 2007-07-20 | 2008-07-21 | Immune modulation via c-type lectin |
Publications (1)
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| ES2557935T3 true ES2557935T3 (es) | 2016-01-29 |
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| ES08776024.5T Active ES2557935T3 (es) | 2007-07-20 | 2008-07-21 | Inmunomodulación mediante lectina de tipo C |
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| HU (1) | HUE026387T2 (enExample) |
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| AU2008294074B2 (en) | 2007-08-30 | 2015-01-22 | Walter And Eliza Hall Institute Of Medical Research | Dendritic cell marker and uses thereof |
| US20110110861A1 (en) * | 2008-05-13 | 2011-05-12 | Mireille Hanna Lahoud | Methods of Detecting Cells with a Disrupted Cell Membrane, Cells Infected with A Pathogen, Dying Cells or Dead Cells |
| WO2010108215A1 (en) * | 2009-03-23 | 2010-09-30 | The Walter And Eliza Hall Institute Of Medical Research | Compounds and methods for modulating an immune response |
| GB201006768D0 (en) | 2010-04-22 | 2010-06-09 | Cancer Rec Tech Ltd | Method for obtaining dendritic cells |
| RU2012152828A (ru) * | 2010-05-07 | 2014-06-20 | Бейлор Рисёч Инститьют | Опосредованное иммунорецепторами дендритных клеток (dcir) перекрестное примирование cd8+ т клеток человека |
| WO2013088136A1 (en) | 2011-12-12 | 2013-06-20 | Ahrens Susan | Ligand for dngr-1 receptor |
| EP2901156B1 (en) | 2012-09-26 | 2018-06-20 | Cook Biotech Incorporated | Medical device design, manufacture and testing systems |
| WO2016011401A1 (en) * | 2014-07-18 | 2016-01-21 | Kedl Ross M | Immunostimulatory combinations and use thereof |
| AU2015294059B2 (en) * | 2014-07-21 | 2019-03-14 | Société des Produits Nestlé S.A. | Nutritional products to promote safe swallowing for individuals with dysphagia |
| CN104789689B (zh) * | 2015-05-13 | 2018-10-02 | 北京泱深生物信息技术有限公司 | 作为肺腺癌诊治靶标的clec9a基因 |
| US20200079860A1 (en) * | 2015-08-06 | 2020-03-12 | Memorial Sloan Kettering Cancer Center | Methods and compositions for tumor therapy |
| CA3013554A1 (en) * | 2016-02-05 | 2017-08-10 | Orionis Biosciences Nv | Targeted therapeutic agents and uses thereof |
| US11661455B2 (en) | 2016-02-05 | 2023-05-30 | Orionis Biosciences BV | Chimeric protein comprising an interferon alpha 2mutant and a PD-L1 binding moiety |
| CN105924501B (zh) * | 2016-04-28 | 2019-04-02 | 郑州大学 | 靶向Clec9a的亲和肽WH肽 |
| US11630103B2 (en) | 2016-08-17 | 2023-04-18 | The Broad Institute, Inc. | Product and methods useful for modulating and evaluating immune responses |
| WO2019032663A1 (en) | 2017-08-09 | 2019-02-14 | Orionis Biosciences Inc. | PD-1 AND PD-L1 BINDING AGENTS |
| JP7347899B2 (ja) | 2017-08-09 | 2023-09-20 | オリオンズ バイオサイエンス インコーポレイテッド | Ｃｄ８結合物質 |
| BR112020002706A2 (pt) * | 2017-08-09 | 2020-08-25 | Orionis Biosciences Inc. | agentes de ligação a clec9a e uso dos mesmos |
| WO2019244973A1 (ja) * | 2018-06-20 | 2019-12-26 | 中外製薬株式会社 | 標的細胞に対する免疫反応を活性化する方法およびその組成物 |
| EP3890773A4 (en) | 2018-11-08 | 2022-11-09 | Orionis Biosciences, Inc. | MODULATION OF DENDRITIC CELL LINES |
| CN113573699A (zh) * | 2019-01-08 | 2021-10-29 | 乔治亚大学研究基金会 | 靶向纳米颗粒以及它们的与真菌感染有关的用途 |
| WO2020179700A1 (ja) * | 2019-03-01 | 2020-09-10 | 国立大学法人筑波大学 | アレルギー疾患を処置することに用いるための組成物 |
| EP3947429A4 (en) | 2019-03-28 | 2023-05-17 | Orionis Biosciences, Inc. | CHIMERIC PROTEIN COMPLEXES BASED ON CLEC9A |
| US20230181758A1 (en) | 2019-07-03 | 2023-06-15 | Codiak Biosciences, Inc. | Extracellular vesicles targeting dendritic cells and uses thereof |
| CN111544592B (zh) * | 2020-03-13 | 2022-05-03 | 中山大学附属第一医院 | 模式识别受体Dectin-1抑制剂对受体移植物的免疫保护及诱导免疫耐受的应用 |
| EP3892739A1 (en) * | 2020-04-09 | 2021-10-13 | Centre Léon Bérard | Type iii interferon for use as a biomarker to predict response to a cancer treatment |
| GB202011859D0 (en) | 2020-07-30 | 2020-09-16 | Francis Crick Institute Ltd | Cytosolic delivery |
| CN119731210A (zh) | 2022-04-21 | 2025-03-28 | 弗朗西斯克里克研究所有限公司 | 双特异性结合剂 |
| EP4558225A1 (en) | 2022-07-21 | 2025-05-28 | The Francis Crick Institute Limited | Immunoconjugate |
| GB202401381D0 (en) | 2024-02-02 | 2024-03-20 | Francis Crick Institute Ltd | Anti-actin antibodies |
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| WO2001055173A2 (en) * | 2000-01-31 | 2001-08-02 | Human Genome Sciences, Inc. | Nucleic acids, proteins, and antibodies |
| US20020090672A1 (en) * | 2000-01-31 | 2002-07-11 | Rosen Craig A. | Nucleic acids, proteins, and antibodies |
| DE10142994A1 (de) * | 2001-09-01 | 2003-03-27 | Keiper Gmbh & Co | Längseinsteller für einen Fahrzeugsitz |
| EP1504099A4 (en) * | 2001-12-10 | 2006-05-10 | Nuvelo Inc | NEW NUCLEIC ACIDS AND POLYPEPTIDES |
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Also Published As
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| CN101896500B (zh) | 2015-09-30 |
| AU2008278831B2 (en) | 2013-11-21 |
| HRP20160033T1 (hr) | 2016-02-26 |
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| SI2185586T1 (sl) | 2016-02-29 |
| JP5577246B2 (ja) | 2014-08-20 |
| US9205153B2 (en) | 2015-12-08 |
| US20140328865A1 (en) | 2014-11-06 |
| HUE026387T2 (en) | 2016-05-30 |
| CN101896500A (zh) | 2010-11-24 |
| WO2009013484A1 (en) | 2009-01-29 |
| JP2010534200A (ja) | 2010-11-04 |
| EP2185586B1 (en) | 2015-10-14 |
| US8580266B2 (en) | 2013-11-12 |
| GB0805159D0 (en) | 2008-04-23 |
| EP2185586A1 (en) | 2010-05-19 |
| CA2693277A1 (en) | 2009-01-29 |
| US20100221265A1 (en) | 2010-09-02 |
| AU2008278831A1 (en) | 2009-01-29 |
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