ES2550101T3 - Inhibidores de proteína quinasa de benzonaftiridinona tricíclica modificada con anillo C y su uso - Google Patents
Inhibidores de proteína quinasa de benzonaftiridinona tricíclica modificada con anillo C y su uso Download PDFInfo
- Publication number
- ES2550101T3 ES2550101T3 ES09765193.9T ES09765193T ES2550101T3 ES 2550101 T3 ES2550101 T3 ES 2550101T3 ES 09765193 T ES09765193 T ES 09765193T ES 2550101 T3 ES2550101 T3 ES 2550101T3
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- Prior art keywords
- naphthyridin
- aryl
- phenyl
- oxo
- ylamino
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- Pain & Pain Management (AREA)
- Oncology (AREA)
- Ophthalmology & Optometry (AREA)
- Gastroenterology & Hepatology (AREA)
- Emergency Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201961P | 2000-05-05 | ||
| US20196108P | 2008-12-17 | 2008-12-17 | |
| PCT/US2009/066319 WO2010077530A1 (en) | 2008-12-17 | 2009-12-02 | C-ring modified tricyclic benzonaphthiridinone protein kinase inhibitors and use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2550101T3 true ES2550101T3 (es) | 2015-11-04 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES09765193.9T Active ES2550101T3 (es) | 2008-12-17 | 2009-12-02 | Inhibidores de proteína quinasa de benzonaftiridinona tricíclica modificada con anillo C y su uso |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US9938268B2 (enExample) |
| EP (1) | EP2367821B1 (enExample) |
| JP (2) | JP2012512246A (enExample) |
| AU (1) | AU2009333653B2 (enExample) |
| CA (1) | CA2745071C (enExample) |
| ES (1) | ES2550101T3 (enExample) |
| IL (1) | IL213588A0 (enExample) |
| WO (1) | WO2010077530A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HRP20181310T1 (hr) | 2011-09-30 | 2018-10-19 | C&C Research Laboratories | Novi heterociklički derivati i njihova uporaba |
| DK3067358T3 (da) | 2012-12-21 | 2019-11-04 | Gilead Sciences Inc | Polycykliske carbamoylpyridon-forbindelser og deres farmaceutiske anvendelse |
| TWI695003B (zh) | 2014-12-23 | 2020-06-01 | 美商基利科學股份有限公司 | 多環胺甲醯基吡啶酮化合物及其醫藥用途 |
| CN115611896A (zh) * | 2021-07-16 | 2023-01-17 | 中国药科大学 | 含四氢萘啶酮或四氢吡啶并嘧啶酮骨架的化合物及其制备方法与制药用途 |
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| JPS4961198A (enExample) * | 1972-10-14 | 1974-06-13 | ||
| US4680298A (en) * | 1983-05-31 | 1987-07-14 | Schering Corporation | Tricyclic anti-allergy and use as anti-inflammatory agents |
| US4596809A (en) * | 1985-03-25 | 1986-06-24 | Schering Corporation | Substituted 1,8-naphthyridinones, useful as anti-allergic agents |
| IL82150A0 (en) * | 1986-04-11 | 1987-10-30 | Schering Corp | Aryl-substituted naphthyridine and pyridopyrazine derivatives and pharmaceutical compositions containing them |
| CA1309658C (en) * | 1986-12-05 | 1992-11-03 | David J. Blythin | Pharmaceutical compositions for treatment of hyperproliferate skin disease |
| EP0459505B1 (en) * | 1990-06-01 | 1996-10-02 | Kyowa Hakko Kogyo Co., Ltd. | Imidazonaphthyridine derivatives |
| JPH0961198A (ja) * | 1995-08-25 | 1997-03-07 | Nippon Seiki Co Ltd | 計器装置 |
| GB9624482D0 (en) | 1995-12-18 | 1997-01-15 | Zeneca Phaema S A | Chemical compounds |
| WO1997030035A1 (en) | 1996-02-13 | 1997-08-21 | Zeneca Limited | Quinazoline derivatives as vegf inhibitors |
| PT885198E (pt) | 1996-03-05 | 2002-06-28 | Astrazeneca Ab | Derivados de 4-anilinoquinazolina |
| GB9718972D0 (en) | 1996-09-25 | 1997-11-12 | Zeneca Ltd | Chemical compounds |
| GB9714249D0 (en) | 1997-07-08 | 1997-09-10 | Angiogene Pharm Ltd | Vascular damaging agents |
| GB9900334D0 (en) | 1999-01-07 | 1999-02-24 | Angiogene Pharm Ltd | Tricylic vascular damaging agents |
| GB9900752D0 (en) | 1999-01-15 | 1999-03-03 | Angiogene Pharm Ltd | Benzimidazole vascular damaging agents |
| AU2001258628A1 (en) | 2000-05-31 | 2001-12-11 | Astrazeneca Ab | Indole derivatives with vascular damaging activity |
| MXPA02012905A (es) | 2000-07-07 | 2004-07-30 | Angiogene Pharm Ltd | Derivados de colquinol como agentes de dano vascular.. |
| BR0112225A (pt) | 2000-07-07 | 2003-05-06 | Angiogene Pharm Ltd | Composto, composição farmacêutica, uso de um composto, e, processo papa preparar um composto |
| ATE478664T1 (de) * | 2000-12-01 | 2010-09-15 | Eisai Inc | Azaphenanthridone-derivate und deren verwendung als parp-inhibitoren |
| WO2004035580A1 (en) | 2002-10-21 | 2004-04-29 | Aprea Ab | Reactivation of wild type p53 in human tumour cells by a low molecular weight compound |
| WO2005118583A1 (en) * | 2004-05-28 | 2005-12-15 | Millennium Pharmaceuticals, Inc. | 2, 5-dihydro-pyrazolo`4, 3-c!quinolin-4-ones as chk-1 inhibitors |
| CA2614257A1 (en) * | 2005-07-22 | 2007-02-08 | Merck & Co., Inc. | Inhibitors of checkpoint kinases |
| WO2008016184A1 (en) | 2006-08-02 | 2008-02-07 | Takeda Pharmaceutical Company Limited | Alpha-carboline derivatives and methods for preparation thereof |
| US7956064B2 (en) | 2006-09-01 | 2011-06-07 | Cylene Pharmaceuticals, Inc. | Fused tricyclic compounds as serine-threonine protein kinase and PARP modulators |
| US8735584B2 (en) * | 2008-02-28 | 2014-05-27 | Merck Patent Gmbh | Protein kinase inhibitors and use thereof |
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2009
- 2009-12-02 AU AU2009333653A patent/AU2009333653B2/en not_active Ceased
- 2009-12-02 JP JP2011542212A patent/JP2012512246A/ja active Pending
- 2009-12-02 WO PCT/US2009/066319 patent/WO2010077530A1/en not_active Ceased
- 2009-12-02 CA CA2745071A patent/CA2745071C/en not_active Expired - Fee Related
- 2009-12-02 US US13/140,090 patent/US9938268B2/en not_active Expired - Fee Related
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- 2009-12-02 ES ES09765193.9T patent/ES2550101T3/es active Active
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2011
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Also Published As
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|---|---|
| EP2367821A1 (en) | 2011-09-28 |
| EP2367821B1 (en) | 2015-09-16 |
| IL213588A0 (en) | 2011-07-31 |
| JP2015163653A (ja) | 2015-09-10 |
| WO2010077530A1 (en) | 2010-07-08 |
| CA2745071C (en) | 2018-08-28 |
| US9938268B2 (en) | 2018-04-10 |
| JP2012512246A (ja) | 2012-05-31 |
| CA2745071A1 (en) | 2010-07-08 |
| US20110312951A1 (en) | 2011-12-22 |
| AU2009333653A1 (en) | 2011-06-30 |
| AU2009333653B2 (en) | 2015-09-10 |
| JP6378138B2 (ja) | 2018-08-22 |
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