ES2547877T3 - Compuestos diaril-oxadiazol - Google Patents

Compuestos diaril-oxadiazol Download PDF

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Publication number
ES2547877T3
ES2547877T3 ES08804975.4T ES08804975T ES2547877T3 ES 2547877 T3 ES2547877 T3 ES 2547877T3 ES 08804975 T ES08804975 T ES 08804975T ES 2547877 T3 ES2547877 T3 ES 2547877T3
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Spain
Prior art keywords
mmol
formula
hplc
title compound
methyl
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ES08804975.4T
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English (en)
Spanish (es)
Inventor
Cyril Montagne
Anna Quattropani
Wolfgang Sauer
Agnès Bombrun
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Merck Serono SA
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Merck Serono SA
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245—Oxadiazoles
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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ES08804975.4T 2007-10-04 2008-10-01 Compuestos diaril-oxadiazol Active ES2547877T3 (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP07117925 2007-10-04
EP07117925 2007-10-04
US99813607P 2007-10-09 2007-10-09
US998136P 2007-10-09
PCT/EP2008/063185 WO2009043890A1 (en) 2007-10-04 2008-10-01 Oxadiazole diaryl compounds

Publications (1)

Publication Number Publication Date
ES2547877T3 true ES2547877T3 (es) 2015-10-09

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ES08804975.4T Active ES2547877T3 (es) 2007-10-04 2008-10-01 Compuestos diaril-oxadiazol

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US (2) US8404676B2 (enExample)
EP (1) EP2193126B1 (enExample)
JP (3) JP5727223B2 (enExample)
KR (1) KR20100083814A (enExample)
CN (2) CN101815707B (enExample)
AR (1) AR068730A1 (enExample)
AU (1) AU2008306886B2 (enExample)
BR (1) BRPI0817597A2 (enExample)
CA (1) CA2696829C (enExample)
EA (1) EA201070423A1 (enExample)
ES (1) ES2547877T3 (enExample)
IL (1) IL204520A (enExample)
MX (1) MX2010003614A (enExample)
WO (1) WO2009043890A1 (enExample)
ZA (1) ZA201001217B (enExample)

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