ES2542344T3 - Uso de inhibidores de tirosina cinasa Syk para el tratamiento de trastornos proliferativos celulares - Google Patents
Uso de inhibidores de tirosina cinasa Syk para el tratamiento de trastornos proliferativos celulares Download PDFInfo
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- ES2542344T3 ES2542344T3 ES07804842.8T ES07804842T ES2542344T3 ES 2542344 T3 ES2542344 T3 ES 2542344T3 ES 07804842 T ES07804842 T ES 07804842T ES 2542344 T3 ES2542344 T3 ES 2542344T3
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- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/22—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
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- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
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- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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| PCT/IB2007/002471 WO2007129226A2 (en) | 2006-05-09 | 2007-05-09 | Use of syk tyrosine kinase inhibitors for the treatment of cell proliferative disorders |
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| DK (1) | DK2026775T3 (enExample) |
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| PL (1) | PL2026775T3 (enExample) |
| PT (1) | PT2026775E (enExample) |
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| PT1546088E (pt) * | 2002-10-03 | 2015-03-16 | Novaremed Ltd | Compostos para utilização no tratamento de doenças auto-imunes, de doenças imuno-alérgicas e de rejeição de órgãos ou tecidos transplantados |
| US7674829B2 (en) * | 2004-03-26 | 2010-03-09 | Novaremed Limited | Compounds for the treatment of AIDS and other viral diseases |
| GB0804213D0 (en) * | 2008-03-06 | 2008-04-16 | New Era Biotech Ltd | A method of printing or preventing pain |
| PL2475361T3 (pl) * | 2009-09-09 | 2020-07-13 | Novaremed Ltd. | N-podstawione benzenopropanoamidy do stosowania w leczeniu bólu i stanu zapalnego |
| US8802734B2 (en) | 2009-09-09 | 2014-08-12 | Novaremed Limited | Method of treating or preventing pain |
| WO2014071109A1 (en) | 2012-11-01 | 2014-05-08 | Infinity Pharmaceuticals, Inc. | Treatment of cancers using pi3 kinase isoform modulators |
| WO2014151386A1 (en) | 2013-03-15 | 2014-09-25 | Infinity Pharmaceuticals, Inc. | Salts and solid forms of isoquinolinones and composition comprising and methods of using the same |
| US20140377258A1 (en) | 2013-05-30 | 2014-12-25 | Infinity Pharmaceuticals, Inc. | Treatment Of Cancers Using PI3 Kinase Isoform Modulators |
| WO2015051241A1 (en) | 2013-10-04 | 2015-04-09 | Infinity Pharmaceuticals, Inc. | Heterocyclic compounds and uses thereof |
| PE20160685A1 (es) | 2013-10-04 | 2016-07-23 | Infinity Pharmaceuticals Inc | Compuestos heterociclicos y usos de los mismos |
| US20160244452A1 (en) | 2013-10-21 | 2016-08-25 | Infinity Pharmaceuticals, Inc. | Heterocyclic compounds and uses thereof |
| CN113620958A (zh) | 2014-03-19 | 2021-11-09 | 无限药品股份有限公司 | 用于治疗PI3K-γ介导的障碍的杂环化合物 |
| WO2015160986A2 (en) | 2014-04-16 | 2015-10-22 | Infinity Pharmaceuticals, Inc. | Combination therapies |
| US9708348B2 (en) | 2014-10-03 | 2017-07-18 | Infinity Pharmaceuticals, Inc. | Trisubstituted bicyclic heterocyclic compounds with kinase activities and uses thereof |
| PH12018500554B1 (en) | 2015-09-14 | 2024-01-24 | Infinity Pharmaceuticals Inc | Solid forms of isoquinolinone derivatives, process of making, compositions comprising, and methods of using the same |
| WO2017214269A1 (en) | 2016-06-08 | 2017-12-14 | Infinity Pharmaceuticals, Inc. | Heterocyclic compounds and uses thereof |
| RU2754507C2 (ru) | 2016-06-24 | 2021-09-02 | Инфинити Фармасьютикалз, Инк. | Комбинированная терапия |
| AU2020242287A1 (en) | 2019-03-21 | 2021-09-02 | INSERM (Institut National de la Santé et de la Recherche Médicale) | A Dbait molecule in combination with kinase inhibitor for the treatment of cancer |
| KR20220098759A (ko) | 2019-11-08 | 2022-07-12 | 인쎄름 (엥스띠뛰 나씨오날 드 라 쌍떼 에 드 라 흐쉐르슈 메디깔) | 키나제 억제제에 대해 내성을 획득한 암의 치료 방법 |
| WO2021148581A1 (en) | 2020-01-22 | 2021-07-29 | Onxeo | Novel dbait molecule and its use |
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| US2908691A (en) * | 1958-07-14 | 1959-10-13 | Searle & Co | Hydroxyphenalkylaminoalkylindoles and ethers corresponding thereto |
| US4766106A (en) * | 1985-06-26 | 1988-08-23 | Cetus Corporation | Solubilization of proteins for pharmaceutical compositions using polymer conjugation |
| US5552558A (en) * | 1989-05-23 | 1996-09-03 | Abbott Laboratories | Retroviral protease inhibiting compounds |
| IS2334B (is) * | 1992-09-08 | 2008-02-15 | Vertex Pharmaceuticals Inc., (A Massachusetts Corporation) | Aspartyl próteasi hemjari af nýjum flokki súlfonamíða |
| GB0115109D0 (en) * | 2001-06-21 | 2001-08-15 | Aventis Pharma Ltd | Chemical compounds |
| PT1546088E (pt) * | 2002-10-03 | 2015-03-16 | Novaremed Ltd | Compostos para utilização no tratamento de doenças auto-imunes, de doenças imuno-alérgicas e de rejeição de órgãos ou tecidos transplantados |
| US7674829B2 (en) * | 2004-03-26 | 2010-03-09 | Novaremed Limited | Compounds for the treatment of AIDS and other viral diseases |
-
2007
- 2007-05-09 ES ES07804842.8T patent/ES2542344T3/es active Active
- 2007-05-09 US US12/227,104 patent/US20090306214A1/en not_active Abandoned
- 2007-05-09 PT PT78048428T patent/PT2026775E/pt unknown
- 2007-05-09 PL PL07804842T patent/PL2026775T3/pl unknown
- 2007-05-09 AU AU2007246779A patent/AU2007246779B2/en not_active Ceased
- 2007-05-09 WO PCT/IB2007/002471 patent/WO2007129226A2/en not_active Ceased
- 2007-05-09 DK DK07804842.8T patent/DK2026775T3/en active
- 2007-05-09 JP JP2009508544A patent/JP5225264B2/ja not_active Expired - Fee Related
- 2007-05-09 EP EP07804842.8A patent/EP2026775B1/en not_active Not-in-force
- 2007-05-09 CA CA2651375A patent/CA2651375C/en not_active Expired - Fee Related
- 2007-05-09 HU HUE07804842A patent/HUE026820T2/en unknown
-
2008
- 2008-11-06 IL IL195152A patent/IL195152A/en active IP Right Grant
-
2012
- 2012-01-06 US US13/344,976 patent/US20120108666A1/en not_active Abandoned
-
2013
- 2013-10-09 US US14/049,454 patent/US20140039060A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| PT2026775E (pt) | 2015-08-05 |
| AU2007246779B2 (en) | 2013-11-28 |
| AU2007246779A1 (en) | 2007-11-15 |
| IL195152A (en) | 2015-10-29 |
| JP5225264B2 (ja) | 2013-07-03 |
| WO2007129226A3 (en) | 2008-05-08 |
| DK2026775T3 (en) | 2015-06-29 |
| US20120108666A1 (en) | 2012-05-03 |
| WO2007129226A2 (en) | 2007-11-15 |
| US20090306214A1 (en) | 2009-12-10 |
| IL195152A0 (en) | 2009-09-22 |
| CA2651375A1 (en) | 2007-11-15 |
| CA2651375C (en) | 2015-12-22 |
| JP2009536191A (ja) | 2009-10-08 |
| PL2026775T3 (pl) | 2015-12-31 |
| US20140039060A1 (en) | 2014-02-06 |
| EP2026775A2 (en) | 2009-02-25 |
| HUE026820T2 (en) | 2016-07-28 |
| EP2026775B1 (en) | 2015-04-29 |
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