ES2535974T3 - Generador de aerosol para la formulación de fármacos - Google Patents
Generador de aerosol para la formulación de fármacos Download PDFInfo
- Publication number
- ES2535974T3 ES2535974T3 ES03705758.5T ES03705758T ES2535974T3 ES 2535974 T3 ES2535974 T3 ES 2535974T3 ES 03705758 T ES03705758 T ES 03705758T ES 2535974 T3 ES2535974 T3 ES 2535974T3
- Authority
- ES
- Spain
- Prior art keywords
- aerosol generator
- camshaft
- aerosol
- housing
- passage
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000443 aerosol Substances 0.000 title claims abstract description 134
- 239000013583 drug formulation Substances 0.000 title description 7
- 239000012530 fluid Substances 0.000 claims abstract description 63
- 239000007921 spray Substances 0.000 claims description 6
- 230000029058 respiratory gaseous exchange Effects 0.000 claims description 3
- 239000004973 liquid crystal related substance Substances 0.000 claims description 2
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 62
- 239000003570 air Substances 0.000 description 51
- 239000003814 drug Substances 0.000 description 29
- 239000012080 ambient air Substances 0.000 description 20
- 229940079593 drug Drugs 0.000 description 16
- 239000007788 liquid Substances 0.000 description 12
- 238000009833 condensation Methods 0.000 description 10
- 230000005494 condensation Effects 0.000 description 10
- 238000010438 heat treatment Methods 0.000 description 9
- 208000007934 ACTH-independent macronodular adrenal hyperplasia Diseases 0.000 description 8
- AAAQKTZKLRYKHR-UHFFFAOYSA-N triphenylmethane Chemical compound C1=CC=CC=C1C(C=1C=CC=CC=1)C1=CC=CC=C1 AAAQKTZKLRYKHR-UHFFFAOYSA-N 0.000 description 8
- BLUGYPPOFIHFJS-UUFHNPECSA-N (2s)-n-[(2s)-1-[[(3r,4s,5s)-3-methoxy-1-[(2s)-2-[(1r,2r)-1-methoxy-2-methyl-3-oxo-3-[[(1s)-2-phenyl-1-(1,3-thiazol-2-yl)ethyl]amino]propyl]pyrrolidin-1-yl]-5-methyl-1-oxoheptan-4-yl]-methylamino]-3-methyl-1-oxobutan-2-yl]-3-methyl-2-(methylamino)butanamid Chemical compound CN[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N(C)[C@@H]([C@@H](C)CC)[C@H](OC)CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@H](C=1SC=CN=1)CC1=CC=CC=C1 BLUGYPPOFIHFJS-UUFHNPECSA-N 0.000 description 6
- ALSTYHKOOCGGFT-KTKRTIGZSA-N (9Z)-octadecen-1-ol Chemical compound CCCCCCCC\C=C/CCCCCCCCO ALSTYHKOOCGGFT-KTKRTIGZSA-N 0.000 description 6
- 238000001514 detection method Methods 0.000 description 6
- 230000006870 function Effects 0.000 description 6
- 210000004072 lung Anatomy 0.000 description 6
- 238000000034 method Methods 0.000 description 6
- 239000002245 particle Substances 0.000 description 6
- ALSTYHKOOCGGFT-UHFFFAOYSA-N cis-oleyl alcohol Natural products CCCCCCCCC=CCCCCCCCCO ALSTYHKOOCGGFT-UHFFFAOYSA-N 0.000 description 5
- 230000007423 decrease Effects 0.000 description 5
- 238000002156 mixing Methods 0.000 description 5
- 230000000694 effects Effects 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 239000002184 metal Substances 0.000 description 4
- 229910052751 metal Inorganic materials 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 230000004913 activation Effects 0.000 description 3
- 230000008859 change Effects 0.000 description 3
- 230000008021 deposition Effects 0.000 description 3
- 238000005259 measurement Methods 0.000 description 3
- 238000012544 monitoring process Methods 0.000 description 3
- 239000002667 nucleating agent Substances 0.000 description 3
- 230000003287 optical effect Effects 0.000 description 3
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 3
- 229910001220 stainless steel Inorganic materials 0.000 description 3
- 239000010935 stainless steel Substances 0.000 description 3
- 230000003213 activating effect Effects 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 238000007906 compression Methods 0.000 description 2
- 230000006835 compression Effects 0.000 description 2
- 239000004020 conductor Substances 0.000 description 2
- 239000010949 copper Substances 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- 239000010931 gold Substances 0.000 description 2
- 239000012052 hydrophilic carrier Substances 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 238000002483 medication Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 230000004044 response Effects 0.000 description 2
- 238000011144 upstream manufacturing Methods 0.000 description 2
- 238000009834 vaporization Methods 0.000 description 2
- 230000008016 vaporization Effects 0.000 description 2
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 239000012159 carrier gas Substances 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 125000004122 cyclic group Chemical group 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000000428 dust Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 230000003434 inspiratory effect Effects 0.000 description 1
- 239000012669 liquid formulation Substances 0.000 description 1
- 239000011344 liquid material Substances 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 229910052987 metal hydride Inorganic materials 0.000 description 1
- 239000006199 nebulizer Substances 0.000 description 1
- 229910052759 nickel Inorganic materials 0.000 description 1
- PXHVJJICTQNCMI-UHFFFAOYSA-N nickel Substances [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 description 1
- -1 nickel metal hydride Chemical class 0.000 description 1
- 230000006911 nucleation Effects 0.000 description 1
- 238000010899 nucleation Methods 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229910052697 platinum Inorganic materials 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 239000003380 propellant Substances 0.000 description 1
- 230000001141 propulsive effect Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
- 239000004065 semiconductor Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 239000011364 vaporized material Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/04—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised
- A61M11/041—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised using heaters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
- A61M15/008—Electronic counters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0091—Inhalators mechanically breath-triggered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0091—Inhalators mechanically breath-triggered
- A61M15/0093—Inhalators mechanically breath-triggered without arming or cocking, e.g. acting directly on the delivery valve
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0091—Inhalators mechanically breath-triggered
- A61M15/0096—Hindering inhalation before activation of the dispenser
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/02—Inhalators with activated or ionised fluids, e.g. electrohydrodynamic [EHD] or electrostatic devices; Ozone-inhalators with radioactive tagged particles
- A61M15/025—Bubble jet droplet ejection devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/005—Sprayers or atomisers specially adapted for therapeutic purposes using ultrasonics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
- A61M15/0081—Locking means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
- A61M15/0083—Timers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B12/00—Arrangements for controlling delivery; Arrangements for controlling the spray area
- B05B12/08—Arrangements for controlling delivery; Arrangements for controlling the spray area responsive to condition of liquid or other fluent material to be discharged, of ambient medium or of target ; responsive to condition of spray devices or of supply means, e.g. pipes, pumps or their drive means
- B05B12/12—Arrangements for controlling delivery; Arrangements for controlling the spray area responsive to condition of liquid or other fluent material to be discharged, of ambient medium or of target ; responsive to condition of spray devices or of supply means, e.g. pipes, pumps or their drive means responsive to conditions of ambient medium or target, e.g. humidity, temperature position or movement of the target relative to the spray apparatus
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Anesthesiology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Nozzles (AREA)
- Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34787202P | 2002-01-15 | 2002-01-15 | |
| US347872P | 2002-01-15 | ||
| US341521 | 2002-06-28 | ||
| US10/341,521 US7458373B2 (en) | 2002-01-15 | 2003-01-14 | Aerosol generator for drug formulation |
| PCT/US2003/001048 WO2003059413A2 (en) | 2002-01-15 | 2003-01-15 | Aerosol generator for drug formulation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2535974T3 true ES2535974T3 (es) | 2015-05-19 |
Family
ID=26992548
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES03705758.5T Expired - Lifetime ES2535974T3 (es) | 2002-01-15 | 2003-01-15 | Generador de aerosol para la formulación de fármacos |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7458373B2 (https=) |
| EP (1) | EP1471955B1 (https=) |
| JP (1) | JP4340155B2 (https=) |
| AU (1) | AU2003207547B2 (https=) |
| CA (1) | CA2472570C (https=) |
| ES (1) | ES2535974T3 (https=) |
| HU (1) | HUE025437T2 (https=) |
| PT (1) | PT1471955E (https=) |
| WO (1) | WO2003059413A2 (https=) |
Families Citing this family (77)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007526796A (ja) * | 2003-12-15 | 2007-09-20 | アレックザ ファーマシューティカルズ， インコーポレイテッド | 薬剤エアロゾル吸入による突出痛の治療 |
| AU2005238962B2 (en) | 2004-04-23 | 2011-05-26 | Philip Morris Products S.A. | Aerosol generators and methods for producing aerosols |
| US20060102175A1 (en) * | 2004-11-18 | 2006-05-18 | Nelson Stephen G | Inhaler |
| CN101184522B (zh) | 2005-05-18 | 2011-12-21 | 尼克塔治疗公司 | 用于支气管内治疗的阀、设备和方法 |
| US7186958B1 (en) * | 2005-09-01 | 2007-03-06 | Zhao Wei, Llc | Inhaler |
| DE602006012862D1 (de) * | 2005-09-26 | 2010-04-22 | Univ Leeds Leeds | Arzneiabgabe |
| GB2433207B (en) * | 2006-02-21 | 2009-01-07 | Jianhe Li | Active suction actuated inhalers with timing devices |
| US8156933B2 (en) * | 2006-06-21 | 2012-04-17 | Puthalath Koroth Raghuprasad | Cloud nebulizer |
| EP2037999B1 (en) | 2006-07-07 | 2016-12-28 | Proteus Digital Health, Inc. | Smart parenteral administration system |
| CN100536951C (zh) * | 2006-11-11 | 2009-09-09 | 达福堡国际有限公司 | 肺内给药装置 |
| WO2008112353A2 (en) * | 2007-02-05 | 2008-09-18 | The Brigham And Women's Hospital, Inc. | Instrumented metered-dose inhaler and methods for predicting disease exacerbations |
| US20080290114A1 (en) * | 2007-05-25 | 2008-11-27 | Honeywell International Inc. | Drug Delivery Flow Controller |
| US9125979B2 (en) | 2007-10-25 | 2015-09-08 | Proteus Digital Health, Inc. | Fluid transfer port information system |
| WO2009067463A1 (en) | 2007-11-19 | 2009-05-28 | Proteus Biomedical, Inc. | Body-associated fluid transport structure evaluation devices |
| JP5570996B2 (ja) | 2007-12-14 | 2014-08-13 | エアロデザインズ インコーポレイテッド | エアロゾル化可能な食料品の送達 |
| US10780241B2 (en) | 2008-08-21 | 2020-09-22 | Vero Biotech LLC | Devices and methods for minimizing and treating high-altitude sickness |
| EP2341942A1 (en) | 2008-09-19 | 2011-07-13 | Nektar Therapeutics | Polymer conjugates of therapeutic peptides |
| WO2010051538A2 (en) * | 2008-10-31 | 2010-05-06 | Microlin, Llc | Liquid atomization device and method |
| US10173019B2 (en) | 2009-12-26 | 2019-01-08 | Inspiro Medical Ltd. | Dry powder delivery device |
| KR20120114368A (ko) | 2010-02-01 | 2012-10-16 | 프로테우스 디지털 헬스, 인코포레이티드 | 양 손목을 이용한 데이터 수집 시스템 |
| KR101798128B1 (ko) | 2010-02-01 | 2017-11-16 | 프로테우스 디지털 헬스, 인코포레이티드 | 데이터 수집 시스템 |
| GB201207054D0 (en) | 2011-09-06 | 2012-06-06 | British American Tobacco Co | Heating smokeable material |
| KR101752639B1 (ko) | 2011-09-06 | 2017-06-30 | 브리티시 아메리칸 토바코 (인베스트먼츠) 리미티드 | 가열식 끽연 가능 물질 |
| RU2614615C2 (ru) | 2011-09-06 | 2017-03-28 | Бритиш Америкэн Тобэкко (Инвестментс) Лимитед | Нагревание курительного материала |
| US9414629B2 (en) | 2011-09-06 | 2016-08-16 | Britsh American Tobacco (Investments) Limited | Heating smokable material |
| KR102196913B1 (ko) | 2011-09-06 | 2020-12-30 | 니코벤처스 트레이딩 리미티드 | 가열식 흡연가능 재료 |
| GB201207039D0 (en) | 2012-04-23 | 2012-06-06 | British American Tobacco Co | Heating smokeable material |
| WO2014004437A1 (en) | 2012-06-25 | 2014-01-03 | Gecko Health Innovations, Inc. | Devices, systems, and methods for adherence monitoring and patient interaction |
| US10034988B2 (en) | 2012-11-28 | 2018-07-31 | Fontem Holdings I B.V. | Methods and devices for compound delivery |
| US9642980B2 (en) | 2013-03-15 | 2017-05-09 | Trudell Medical International | Ventilator circuit, adapter for use in ventilator circuit and methods for the use thereof |
| US9918496B2 (en) | 2013-07-24 | 2018-03-20 | Altria Client Services Llc | Electronic smoking article |
| MX358899B (es) | 2013-08-28 | 2018-09-07 | Gecko Health Innovations Inc | Dispositivos, sistemas y métodos para monitoreo de adherencia y dispositivos, sistemas y métodos para monitorear el uso de dispensadores de consumibles. |
| US10194693B2 (en) | 2013-09-20 | 2019-02-05 | Fontem Holdings 1 B.V. | Aerosol generating device |
| RU2646731C2 (ru) | 2013-10-29 | 2018-03-06 | Бритиш Америкэн Тобэкко (Инвестментс) Лимитед | Устройство для нагревания курительного материала |
| US10292424B2 (en) * | 2013-10-31 | 2019-05-21 | Rai Strategic Holdings, Inc. | Aerosol delivery device including a pressure-based aerosol delivery mechanism |
| US10286163B1 (en) | 2014-03-04 | 2019-05-14 | Philip J. Paustian | On demand aerosolized delivery inhaler |
| NO2709641T3 (https=) | 2014-03-10 | 2018-05-12 | ||
| US10300228B2 (en) * | 2014-08-26 | 2019-05-28 | Innovosciences, Llc | Thermal modulation of an inhalable medicament |
| US10737042B2 (en) | 2014-08-26 | 2020-08-11 | Michael Edward Breede | Thermal modulation of an inhalable medicament |
| GB201511349D0 (en) | 2015-06-29 | 2015-08-12 | Nicoventures Holdings Ltd | Electronic aerosol provision systems |
| GB201511361D0 (en) | 2015-06-29 | 2015-08-12 | Nicoventures Holdings Ltd | Electronic vapour provision system |
| JP6818008B2 (ja) | 2015-07-20 | 2021-01-20 | パール セラピューティクス，インコーポレイテッド | エアロゾル送達システムおよび関連する方法 |
| US20170055584A1 (en) | 2015-08-31 | 2017-03-02 | British American Tobacco (Investments) Limited | Article for use with apparatus for heating smokable material |
| US11924930B2 (en) | 2015-08-31 | 2024-03-05 | Nicoventures Trading Limited | Article for use with apparatus for heating smokable material |
| US20170119046A1 (en) | 2015-10-30 | 2017-05-04 | British American Tobacco (Investments) Limited | Apparatus for Heating Smokable Material |
| US12042809B2 (en) | 2015-11-02 | 2024-07-23 | Altria Client Services Llc | Aerosol-generating system comprising a vibratable element |
| CN108135274B (zh) * | 2015-11-02 | 2022-01-07 | 菲利普莫里斯生产公司 | 包括可振动元件的气溶胶生成系统 |
| EP3452150B1 (en) | 2016-05-03 | 2024-01-17 | Pneuma Respiratory, Inc. | Droplet delivery device for delivery of fluids to the pulmonary system |
| WO2017192773A1 (en) | 2016-05-03 | 2017-11-09 | Pneuma Respiratory, Inc. | Methods for treatment of pulmonary lung diseases with improved therapeutic efficacy and improved dose efficiency |
| EP4624054A3 (en) | 2016-05-03 | 2025-11-19 | Pneuma Respiratory, Inc. | Methods for generating and delivering droplets to the pulmonary system using a droplet delivery device |
| WO2017192782A1 (en) | 2016-05-03 | 2017-11-09 | Pneuma Respiratory, Inc. | Systems and methods comprising a droplet delivery device and a breathing assist device for therapeutic treatment |
| WO2017192774A1 (en) | 2016-05-03 | 2017-11-09 | Pneuma Respiratory, Inc. | Methods for the systemic delivery of therapeutic agents to the pulmonary system using a droplet delivery device |
| GB201612945D0 (en) | 2016-07-26 | 2016-09-07 | British American Tobacco Investments Ltd | Method of generating aerosol |
| CA3026391A1 (en) * | 2016-08-10 | 2018-02-15 | Gary Stephen Shuster | Vaporization improvements |
| WO2018213834A1 (en) | 2017-05-19 | 2018-11-22 | Pneuma Respiratory, Inc. | Dry powder delivery device and methods of use |
| WO2018216019A1 (en) * | 2017-05-25 | 2018-11-29 | Ian Solomon | Apparatus for delivering a liquid aerosol to oral cavity surfaces |
| GB2564407A (en) * | 2017-07-06 | 2019-01-16 | Corefox Oy | Portable inhalator device |
| CN111526914A (zh) | 2017-10-04 | 2020-08-11 | 精呼吸股份有限公司 | 电子呼吸致动式直线型液滴输送装置及其使用方法 |
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-
2003
- 2003-01-14 US US10/341,521 patent/US7458373B2/en not_active Expired - Lifetime
- 2003-01-15 PT PT3705758T patent/PT1471955E/pt unknown
- 2003-01-15 JP JP2003559573A patent/JP4340155B2/ja not_active Expired - Lifetime
- 2003-01-15 ES ES03705758.5T patent/ES2535974T3/es not_active Expired - Lifetime
- 2003-01-15 CA CA2472570A patent/CA2472570C/en not_active Expired - Lifetime
- 2003-01-15 HU HUE03705758A patent/HUE025437T2/en unknown
- 2003-01-15 AU AU2003207547A patent/AU2003207547B2/en not_active Ceased
- 2003-01-15 EP EP03705758.5A patent/EP1471955B1/en not_active Expired - Lifetime
- 2003-01-15 WO PCT/US2003/001048 patent/WO2003059413A2/en not_active Ceased
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|---|---|
| WO2003059413A2 (en) | 2003-07-24 |
| JP2006501871A (ja) | 2006-01-19 |
| HUE025437T2 (en) | 2016-05-30 |
| WO2003059413A3 (en) | 2003-11-13 |
| US7458373B2 (en) | 2008-12-02 |
| AU2003207547B2 (en) | 2008-07-03 |
| EP1471955A2 (en) | 2004-11-03 |
| JP4340155B2 (ja) | 2009-10-07 |
| PT1471955E (pt) | 2015-04-27 |
| EP1471955A4 (en) | 2010-11-03 |
| EP1471955B1 (en) | 2015-03-04 |
| CA2472570A1 (en) | 2003-07-24 |
| CA2472570C (en) | 2013-02-26 |
| US20030230303A1 (en) | 2003-12-18 |
| AU2003207547A1 (en) | 2003-07-30 |
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